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Abstract 315: Feasibility of outpatient ambulatory ECG monitoring to screen for silent atrial fibrillation: Pilot Findings from Screening Trial for Undiagnosed Atrial Fibrillation (STUDY-AF) Poster Session III
CONCLUSION: Ambulatory screening of asymptomatic arrhythmias using the Zio® Patch is feasible; however the diagnostic yield for silent AF may be low, even among patients with established AF risk factors. Our study found a high prevalence of incidental asymptomatic SVT and NSVT. A larger trial with more targeted enrollment may be required to demonstrate the value of screening for AF. The impact of detecting incidental NSVT or SVT, which themselves could prompt evaluation and may be relevant to development of AF, requires further investigation.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Ullal, A. J., Hoang, D. D., Than, C., Heidenreich, P. A., Miller, J. D., Friday, K., Froelicher, V. F., Turakhia, M. P. Tags: Poster Session III Source Type: research

Abstract 63: The Smoking Paradox in Patients Hospitalized with Coronary Artery Disease: Findings from Get With The Guidelines - CAD Poster Session I
Conclusion: Smoking continues to be a major risk factor for presenting with CAD at a much younger age and with fewer risk factors. It is likely that the continued modest association with lower in-hospital mortality in smokers in this analysis after adjustment reflects residual or unmeasured confounding. This apparent smoker’s paradox in CAD should not be interpreted as a benefit of cigarette smoking.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Ali, S. F., Smith, E. E., Bhatt, D. L., Pan, W., Fonarow, G. C., Schwamm, L. H. Tags: Poster Session I Source Type: research

Abstract 96: Sex Differences in Pre-Event Health Status of Young Patients with Acute Myocardial Infarction: The VIRGO Study Poster Session I
Conclusion: Compared with men, young women presenting with an AMI seem to have worse health status with poorer physical functioning and quality of life prior to their event. In light of these findings, it may be useful for healthcare providers to identify young women who are at increased cardiovascular risk at an earlier stage in order to optimize their health status.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Dreyer, R. P., Smolderen, K. G., Strait, K. M., Beltrame, J. F., Lichtman, J. H., Lorenze, N. P., D'Onofrio, G., Krumholz, H. M., Spertus, J. A. Tags: Poster Session I Source Type: research

Abstract 150: Resource Utilization Patterns and Outcomes Among Acute Coronary Syndrome Patients: Findings From a Multi-Payer Analysis Poster Session II
Conclusion: These findings suggest that many patients with ACS do not receive appropriate recommended antithrombotic prophylaxis, and opportunities exist to improve therapy. Increased use of software tools such as AQuA may support enhanced education efforts aimed at improving adherence to guidelines and quality of care.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Lang, K., Bozkaya, D., Patel, A. A., Macomson, B., Crivera, C., Owens, G., Mody, S. Tags: Poster Session II Source Type: research

Abstract 205: New Onset Heart Failure and Adverse Ischemic Events Associated with Amiodarone and Dronedarone Use among Atrial Fibrillation Patients Poster Session II
Conclusions: In a propensity score matched observational cohort study, amiodarone use was associated with higher incidence rate of new onset HF, HF hospitalizations, and TIA as identified from claims. This finding differs from other clinical studies. Future observational cohort studies should incorporate medical record review for validation since information from claims might be insufficient to fully account for underlying patient risk status, or accurately determine if HF was new onset.Key words: amiodarone; dronedarone; atrial fibrillation; heart failure.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Sylwestrzak, G., Liu, J., Rosenberg, A., White, J., Barron, J., Redberg, R., Malenka, D. Tags: Poster Session II Source Type: research

Abstract 213: The Smoking Paradox in Acute Ischemic Stroke: Findings from Get With The Guidelines - Stroke Poster Session II
Conclusion: Smoking continues to be a major risk factor for presenting with acute ischemic stroke at a much younger age and with fewer vascular risk factors. The association with lower in-hospital mortality, even after covariate adjustment, may represent residual confounding due to the marked age differences and unmeasured confounding or it may reflect a protective association. Further research is warranted.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Ali, S. F., Smith, E. E., Bhatt, D. L., Pan, W., Fonarow, G. C., Schwamm, L. H. Tags: Poster Session II Source Type: research

Abstract 217: How well does the CHADS2 Stroke Risk Score Predict Major Hemorrhage in Patients with Atrial Fibrillation? Poster Session II
Conclusions: Although some clinical markers of stroke risk such as those included in the CHADS2 risk score are also associated with increased hemorrhage risk, the CHADS2 risk score should not be used instead of a validated hemorrhage risk tool to estimate hemorrhage risk.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Quinn, G. R., Singer, D. E., Go, A. S., Chang, Y., Borowsky, L., Pomernacki, N., Udaltsova, N., Fang, M. C. Tags: Poster Session II Source Type: research

Abstract 227: Prescribing Warfarin at Discharge for Heart Failure Patients without Atrial Fibrillation Findings from the Get With The Guidelines-Heart Failure Registry Poster Session II
Conclusions: Approximately 1 in 10 HF patients without AF or other documented indications are prescribed warfarin at discharge, and prescription rates vary widely across hospitals. Further research is needed to understand why anticoagulation is prescribed to patients with HF in the absence of documented indications.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Eapen, Z., Grau-Sepulveda, M., Fonarow, G., Heidenreich, P., Peterson, E., Hernandez, A. Tags: Poster Session II Source Type: research

Abstract 239: Rates of Atrial Fibrillation Diagnoses and Stroke Events by Combination of Risk Factors Poster Session II
Conclusions: Results from a very large sample of patients in a claims database confirm increased rates of AF and stroke in patients with known risk ractors, while adding to the knowledge base regarding the risk levels among many less prevalent combinations of these factors. The results suggest that patients should be monitored more vigilantly as age progresses for signs of AF, and possibly treated more aggressively for risk factors that increase the incidence of AF and stroke. In particular, patients age 75+ may be considered to be at risk based on age alone.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Turakhia, M. P., Hunter, T. D., Mollenkopf, S. A., Reynolds, M. R. Tags: Poster Session II Source Type: research

Abstract 251: Risk Factors for Recurrence of Cardiovascular Events Following Acute Coronary Syndrome: Longitudinal Analysis from 2006-2011 Poster Session III
Conclusion: Following an ACS event, patients with pre-admission statin use or a prior CABG had decreased risk, while older patients or those with baseline comorbidities had increased risk of an adverse CV event occurring sooner. Ultimately, identifying high-risk ACS subgroups may facilitate tailored and more aggressive treatment to improve outcomes.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Reddy, V. S., Luthra, R., Xu, Y., Wilhelm, K., Power, T. P., Fisher, M. D., Cziraky, M. J. Tags: Poster Session III Source Type: research

Priorities for Comparative Effectiveness Reviews in Cardiovascular Disease Original Articles
Conclusions— Using a systematic process deriving consensus from multiple stakeholders across cardiovascular disease states, we generated a prioritized list of evidence synthesis topics to inform decision makers. The topics vetted through this process seek to determine the comparative safety and effectiveness of a range of treatments, both established and emerging, and are immediately relevant for prevalent disease states.
Source: Circulation: Cardiovascular Quality and Outcomes - March 19, 2013 Category: Cardiology Authors: Eapen, Z. J., McBroom, A. J., Gray, R., Musty, M. D., Hadley, C., Hernandez, A. F., Sanders, G. D. Tags: Health policy and outcome research, Congestive, Cerebrovascular disease/stroke, Acute coronary syndromes, Arrhythmias, clinical electrophysiology, drugs Original Articles Source Type: research

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