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Nonsteroidal Anti-Inflammatory Drugs and Cardiovascular Outcomes in Women: Results From the Women's Health Initiative Original Articles
Conclusions— Regular use of selective cox-2 inhibitors and nonselective NSAIDs with cox-2>cox-1 inhibition showed a modestly increased hazard for cardiovascular events. Nonselective agents with cox-1>cox-2 inhibition were not associated with increased cardiovascular risk. Clinical Trial Registration— URL: www.clinicaltrials.gov. Unique identifier: NCT00000611.
Source: Circulation: Cardiovascular Quality and Outcomes - July 15, 2014 Category: Cardiology Authors: Bavry, A. A., Thomas, F., Allison, M., Johnson, K. C., Howard, B. V., Hlatky, M., Manson, J. E., Limacher, M. C. Tags: Risk Factors Original Articles Source Type: research

Abstract 304: Nonfatal Outcomes Following Incident Atrial Fibrillation: A Community Study Session Title: Poster Session III
Conclusions: In the community, adverse outcomes are frequent after AF, and HF occurs more frequently than IS/TIA. Risk factors differed for IS/TIA and HF, suggesting that pathways to the occurrence of these outcomes, as well as prevention strategies, may differ. Finally, the occurrence of these outcomes did not decline over the last decade, highlighting the importance of continued rigorous surveillance of adverse outcomes in AF.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Chamberlain, A. M., Gersh, B. J., Alonso, A., Brown, R. D., Weston, S. A., Roger, V. L. Tags: Session Title: Poster Session III Source Type: research

Abstract 312: Anatomic Runoff Score Predicts Cardiovascular Outcomes in Patients with Lower Extremity Peripheral Artery Disease Session Title: Poster Session III
Conclusions: After adjustment for clinical factors, the LE-PAD anatomic runoff score, age and indication for procedure were the most significant predictors of future cardiovascular morbidity and mortality in a broadly-representative patient population undergoing revascularization for symptomatic PAD. The use of a clinically useful anatomic scoring system, if validated, may assist clinicians in risk-stratifying patients during the course of clinical decision-making.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Jones, W. S., Patel, M. R., Tsai, T. T., Go, A. S., Gupta, R., Hedayati, N., Ho, P. M., Jazaeri, O., Rogers, R. K., Shetterly, S. M., Wagner, N. M., Magid, D. J. Tags: Session Title: Poster Session III Source Type: research

Abstract 340: Thirty-day Repeat Hospitalizations for Patients Treated with Prasugrel Compared to Ticagrelor following Acute Coronary Syndrome: Findings from a Large Hospital Charge Master Database Session Title: Poster Session III
Conclusion: Rehosp for MI, revasc or bleeding was non-inferior for pras compared to ticag at 30 days post discharge. Pts treated with pras had lower 30 day rehosp rates, particularly related to readmission for MI, compared with ticag. Although limited by selection bias, these results support the clinical utility of pras, regardless of cohort, to limit 30 day rehosp for pts undergoing PCI for ACS.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Vetrovec, G. W., Larmore, C., Molife, C., DeKoven, M., Karkare, S., Zhu, Y. E., Frech-Tamas, F., Lu, J., Lee, W. C., Mc Collam, P., Marrett, E., Effron, M. B. Tags: Session Title: Poster Session III Source Type: research

Abstract 20: Public Reporting of Mortality Rates for Cardiovascular Conditions Did Not Improve Patient Outcomes Session Title: Concurrent II Session A: Oral Abstracts on Policy Issues
Conclusions: We found that mortality rates for publicly reported conditions were improving slightly during the period when only processes of care were being reported, but that these improvements slowed or reversed once public reporting of mortality rates began. These findings suggest that public reporting may be necessary, but is clearly not sufficient, to improve patient outcomes.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Joynt, K. E., Orav, E. J., Jha, A. K. Tags: Session Title: Concurrent II Session A: Oral Abstracts on Policy Issues Source Type: research

Abstract 102: Major Adverse Cardiovascular Events in U.S. Coronary Heart Disease and Acute Coronary Syndrome Patients Session Title: Poster Session I
Conclusions: CHD and ACS are resource intensive diseases in the first year after index episode, with most costs related to hospitalizations. Outpatient cardiovascular drug costs make up a small proportion of the total costs.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Ariely, R., Korsnes, J. S., Mitra, D., Davis, K. L., Bell, C. Tags: Session Title: Poster Session I Source Type: research

Abstract 110: Long-Term Health Status Outcomes in Young Women with Acute Myocardial Infarction: Results from the VIRGO Study Session Title: Poster Session I
Conclusion: Compared with men, young women are more likely to have "poor" health status outcomes after AMI. This information is critically important in developing targets for gender-specific interventions to improve young women’s recovery post AMI.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Dreyer, R. P., Strait, K. M., Lichtman, J. H., Lorenze, N., D'Onofrio, G., Bueno, H., Spertus, J. A., Krumholz, H. M. Tags: Session Title: Poster Session I Source Type: research

Abstract 132: The POWR Survey: Patient and Physician Perspectives on Outcomes Weighting in Revascularization. Session Title: Poster Session I
Conclusions: Patients and physicians agree on which outcomes are most (death and stroke)and least impactful (incision scar), but there is a lot of variability in between supporting the reporting of more adverse outcomes and not just those included in MACE.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Pandit, J. A., Gupta, V., Boyer, N., Ports, T. A., Yeghiazarians, Y., Boyle, A. J. Tags: Session Title: Poster Session I Source Type: research

Abstract 151: Outcomes Associated With Prophylactic Amiodarone Protocol in Patients Undergoing Cardiac Surgery: A Single Center Experience Session Title: Poster Session I
Conclusions: Implementation of an amiodarone prophylaxis protocol order care set was associated with greater utilization of amiodarone. It was also associated with a modest decrease in the incidence of STS-defined POAF, stroke and MI but was not associated with a change in 30-day mortality in patients undergoing cardiac surgery. Further studies are needed to study the cost-effectiveness and risk-benefit analysis of routine amiodarone as prophylaxis.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Atreya, A. R., Arora, S., Garb, J., Rousou, J., Lindenauer, P., Lotfi, A. Tags: Session Title: Poster Session I Source Type: research

Abstract 178: Females with Cardiac Comorbidities Have Worse Outcome Compared to Males Presenting with Unexplained Syncope: An ACAP-SELF Dataset Analysis Session Title: Poster Session I
Conclusions: The SELF-pathway for patients with syncope helps identify at-risk subgroups in our patient population. Females with SELF-2 criteria (Structural heart disease, abnormal ECG, arrhythmia) had significantly worse long-term outcome compared to males regardless of manner of syncopal presentation.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Pratap, B., Bastawrose, J., Gurram, A., Panneerselvam, N., Lingannan, A., Kalamkar, P., Patel, D., Verzosa, J., Shahanoor, Z., Umali, T., Pamidimukala, C., Pierce, M., Aziz, E. F., Herzog, E. Tags: Session Title: Poster Session I Source Type: research

Abstract 185: The Sex Gap among Cardiovascular Disease Encounters in India Session Title: Poster Session I
Conclusion: Untreated or poorly managed AF and CAD can lead to myocardial infarction, stroke and death. A greater awareness of gender differences in AF and CAD, and the impact of factors that are unique to each gender, would contribute to more effective management and better long-term outcomes.Though genetic differences may contribute to greater cardiovascular disease prevalence in men, PINNACLE India’s sizable difference in male and female representation could be indicative of cultural or economic issues limiting access to specialty care for females. Implementing dedicated efforts to understand and reduce gaps in ac...
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Vicera, V. D., Glusenkamp, N. T., Risch, S. A., Kerkar, P., Kumar, G., Oetgen, W. J. Tags: Session Title: Poster Session I Source Type: research

Abstract 201: Gemfibrozil In Combination With Statin Is Associated With Reduction In All Cause Mortality: A Retrospective Cohort Study Session Title: Poster Session II
Conclusion: Combination of gemfibrozil with statin is associated with greater reduction in all cause mortality compared to statins alone.Keywords: gemfibrozil, mortality
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Aryal, S. R., Newman, W. Tags: Session Title: Poster Session II Source Type: research

Abstract 207: Gender Differences in Pre-Event Health Status of Young Patients with Acute Myocardial Infarction: Insights from the VIRGO Study Session Title: Poster Session II
Conclusion: Young women with an AMI have poorer health status prior to their event than men. This suggests worse symptom control prior to an AMI and underscores the need to adjust for baseline health status in evaluations of gender-based disparities in young AMI patients.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Dreyer, R. P., Smolderen, K. G., Strait, K. M., Beltrame, J. F., Lichtman, J. H., Lorenze, N., D'Onofrio, G., Bueno, H., Krumholz, H. M., Spertus, J. A. Tags: Session Title: Poster Session II Source Type: research

Abstract 223: Patients With Cardiac Comorbidities Carry Worse Outcome as Identified by Our SELF Risk Stratification Pathway: An ACAP-SELF Syncope Dataset Analysis Session Title: Poster Session II
Conclusions: Using the SELF-pathway for patients presenting with syncope effectively identifies high risk patients who merit hospitalization and close follow-up post-discharge. These include patients with structural heart disease, abnormal EKG and abnormal telemetry, as well as patients with diabetes, CAD and CHF. This has important implications for the evaluation of a common disease that poses a significant economic burden on healthcare systems.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Pratap, B., Bastawrose, J., Pamidimukala, C. K., Patel, D., Kalamkar, P., Lingannan, A., Panneerselvam, N., Gurram, A., Patel, S., Pierce, M., Ghosh, H., Herzog, E., Aziz, E. Tags: Session Title: Poster Session II Source Type: research

Abstract 232: Comparison of Different Management Strategies for Acute Myocardial Infarction: A Multivariable Network Meta-analysis Session Title: Poster Session II
Conclusions: Primary PCI is the preferred approach for treatment of STEMI. Our analysis suggests that a pharmacoinvasive approach may be more effective and safer as compared to facilitated PCI and thrombolytic therapy.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Fazel, R., Nallamothu, B. K. Tags: Session Title: Poster Session II Source Type: research

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