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Lessons from the Space-2 trial in preventing carotid artery stroke in medically managed patients
The SPACE-2 trial, led by Dr Tilman Reiff1 from Heidelberg University, was a multi-center, randomized, controlled trial including 36 centers in Austria, Germany, and Switzerland. It aimed to directly compare the benefit of intervention vs best medical therapy (BMT) in patients with high-grade asymptomatic carotid artery stenosis. Interventions considered were carotid endarterectomy (CEA) and carotid artery stenting (CAS). Participants were between the ages of 50 and 85  years with at least 70% internal carotid artery stenosis.
Source: Journal of Vascular Surgery - March 7, 2023 Category: Surgery Authors: Young Erben, Thomas G. Brott Source Type: research

The Challenge of Preventing Carotid Artery Stroke in Properly Medically Managed Patients: Lessons From SPACE-2
The SPACE-2 trial led by Dr. Tilman Reiff(1) from Heidelberg University was a multi-center, randomized, controlled trial including 36 centers in Austria, Germany and Switzerland. It aimed to directly compare the benefit of intervention versus best medical therapy (BMT) in high-grade asymptomatic carotid artery stenosis patients. Interventions considered were carotid endarterectomy (CEA) and carotid artery stenting (CAS). Participants were between the ages of 50 and 85 years with at least 70% internal carotid artery stenosis.
Source: Journal of Vascular Surgery - March 7, 2023 Category: Surgery Authors: Young Erben, Thomas G. Brott Source Type: research