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Lower 25-hydroxyvitamin D is associated with severer white matter hyperintensity and cognitive function in patients with non-disabling ischemic cerebrovascular events
Vascular cognitive impairment (VCI) is the second most common type of cognitive impairment, referring to the entire spectrum of cognitive impairment contributed by cerebrovascular pathology1. Due to the progressively higher incidence of stroke and cerebrovascular diseases, VCI, including post-stroke cognitive impairment are the leading causes of disability epidemic worldwide2-3. White matter lesions, manifested as white matter hyperintensities (WMH) on T2-weighted magnetic resonance imaging (MRI) scans, are one of the most common pathological characteristics of VCI4.
Source: Journal of Stroke and Cerebrovascular Diseases - August 31, 2023 Category: Neurology Authors: Zhengsheng Gu, Xu Sun, Chenghao Wu, Binghan Li, Jingjing Chen, Weisen Wang, Xin Gao, Yuhao Tan, Bin Li, Ge Yin, Yawen Xu, Chenrui Song, Bingying Du, Xiaoying Bi Source Type: research

Mobile point-of-care MRI demonstration of a normal volunteer in a telemedicine-equipped ambulance
Several centers have implemented ambulances equipped with CT scanners and telemedicine capabilities, known as mobile stroke units (MSU), to expedite acute stroke care delivery in the pre-hospital setting. While MSUs have been shown to improve outcomes compared with standard emergency medical management, there are limitations to incorporating CT, including radiation exposure to emergency medical services personnel. Recently, a portable, low-field strength MRI (Swoop ®, Hyperfine, Inc., Guilford, CT) received FDA clearance for in-hospital use.
Source: Journal of Stroke and Cerebrovascular Diseases - August 12, 2023 Category: Neurology Authors: Donna R. Roberts, Todd McGeorge, Dave Abrams, Russell Hewitt, Dustin LeBlanc, William Dennis, Mark Rosenberg, Sami Al Kasab, Christine Holmstedt, Maria V. Spampinato, Sam Torres-Rosado, Richard Ancrum, Michael Haschker, Jillian Harvey Source Type: research

Time to ct scan imaging after symptom onset among ischeamic stroke patients presenting to a quaternary hospital in ghana
This study sought to determine the time of onset of symptoms to the time a CT imaging was done among patients presenting with acute stroke at the Korle-Bu Teaching Hospital.
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2023 Category: Neurology Authors: F. Duodu, D. Brodie Mends, B. Agbinko-Djobalar, P. Pekyi-Boateng, M. Amerwornu, P Adjei, A Akpalu, K Nkromah Source Type: research

An unusual neurological presentation in a patient with primary hypereosinophilic syndrome
Hypereosinophilic syndromes are characterized by an increased number of blood eosinophils (usually more than 1.5  × 109) infiltrating tissues and causing organ damage through over-production of pro-inflammatory cytokines with heterogeneous clinical presentation. Here we present a case of a 47 years old male, with an unremarkable previous medical history, with a sudden onset of subungual hemorrhage and low b ack pain. Admitted for right arm weakness and vomiting, was raised the suspicion of acute cerebrovascular syndrome, but a brain CT scan with angiogram and perfusion sequences did not show any signs of early ischaemic...
Source: Journal of Stroke and Cerebrovascular Diseases - September 5, 2022 Category: Neurology Authors: E. Spina, G.T. Maniscalco, A. Petraroli, A. Detoraki, G. Servillo, A. Ranieri, A. De Mase, R. Renna, P. Candelaresi, A. De Paulis, V. Andreone Tags: Case Report Source Type: research

Infratentorial developmental venous anomaly concurrent with a cavernoma and dural arteriovenous fistula
A 32-year-old woman underwent a head computed tomography scan after a traffic accident. A calcification in the left cerebellar hemisphere was disclosed. She did not complain of any symptoms, but neurological examination revealed cerebellar ataxia. She did not have any preceding episodes since birth, such as acute-onset headache. Magnetic resonance imaging showed past hemorrhage of the calcification lesion suggestive of a cerebellar cavernoma. A dilated vascular structure was also observed (Fig.  1A, B).
Source: Journal of Stroke and Cerebrovascular Diseases - July 14, 2022 Category: Neurology Authors: Hirokuni Hashikata, Yoshinori Maki, Ryota Ishibashi, Masanori Goto, Hiroki Toda Tags: Case Report Source Type: research

Volumetric White Matter Hyperintensity Ranges Correspond to Fazekas Scores on Brain MRI
Leukoaraiosis presents as white matter hyperintensities (WMH) on magnetic resonance (MR) imaging. It is thought to originate from decreased vascular supply to axons with an accompanying loss of axonal integrity. WMH have been found to be more prevalent in older patients, especially in those with neurodegeneration from Alzheimer's disease (AD) or stroke.1-6A visual categorization method named the Fazekas scale was developed in order to compare white matter disease burden on computed tomography scans between patients experiencing normal aging and those with AD.
Source: Journal of Stroke and Cerebrovascular Diseases - February 11, 2022 Category: Neurology Authors: Ariana Andere, Gaurav Jindal, Janine Molino, Scott Collins, Derek Merck, Tina Burton, Christoph Stretz, Shadi Yaghi, Daniel C. Sacchetti, Sleiman El Jamal, Michael E. Reznik, Karen Furie, Shawna Cutting Tags: Short Communication Source Type: research

Diagnostic and Prognostic Blood Biomarkers in Transient Ischemic Attack and Minor Ischemic Stroke: An Up-To-Date Narrative Review
Transient ischemic attack (TIA) is a brief episode of focal neurological deficit, lasting less than 24 hours, and reaching its climax usually within minutes. Patients with an even tiny ischemic brain lesion on imaging are considered, on tissue-based criteria, to have a minor ischemic stroke (MIS), usually with mild and non-disabling symptoms.1 Although a consensus clinical definition for MIS is currently lacking, 5 working definitions based on information from head computed tomography (CT) scan and clinical examination have been developed by the National Institute of Neurological Disorder and Stroke (NINDS) rt-PA stroke study Investigators.
Source: Journal of Stroke and Cerebrovascular Diseases - January 10, 2022 Category: Neurology Authors: Matteo Foschi, Marina Padroni, Samir Abu-Rumeileh, Ahmed Abdelhak, Michele Russo, Lucio D'Anna, Maria Guarino Tags: Review Article Source Type: research

Novel Approaches to Detection of Cerebral Microbleeds: Single Deep Learning Model to Achieve a Balanced Performance
Cerebral microbleeds (CMBs) are considered essential indicators for the diagnosis of cerebrovascular disease and cognitive disorders. Traditionally, CMBs are manually interpreted based on criteria including the shape, diameter, and signal characteristics after an MR examination, such as susceptibility-weighted imaging or gradient echo imaging (GRE). In this paper, an efficient method for CMB detection in GRE scans is presented.
Source: Journal of Stroke and Cerebrovascular Diseases - June 24, 2021 Category: Neurology Authors: Min Jae Myung, Kyung Mi Lee, Hyug-Gi Kim, Janghoon Oh, Ji Young Lee, Ilah Shin, Eui Jong Kim, Jin San Lee Source Type: research

Early Triage of Cardioembolic Sources Using Chest Spectral Computed Tomography in Acute Ischemic Stroke
The present study investigated the potential usefulness of delayed-phase, low-dose, non-gated, chest spectral CT scans (DSCT) for the early triage of cardioembolic (CE) sources in patients admitted with acute ischemic stroke (AIS), and for the simultaneous detection of myocardial disease and thrombotic complications.
Source: Journal of Stroke and Cerebrovascular Diseases - March 19, 2021 Category: Neurology Authors: Gaston A. Rodr íguez-Granillo, Juan J. Cirio, Celina Ciardi, Maria Laura Caballero, Marcos Ceron, Carlos Bleise, Pablo Diluca, Pedro Lylyk Source Type: research

Bilateral large vessel occlusion causing massive ischemic stroke in a covid-19 patient
The case of a 70-year-old male presenting an ischemic stroke related to COVID-19 infection is described. He was initially admitted to the hospital with respiratory insufficiency syndrome secondary to pneumonia caused by SARS Co2. In the next days, he developed rapid neurological deterioration characterized by drowsiness which progressed to deep coma. D-dimer was elevated. Brain CT scan showed bilateral massive ischemic stroke located in the anterior circulation, CT angiogram showed occlusion in the left internal carotid artery and the right middle cerebral artery.
Source: Journal of Stroke and Cerebrovascular Diseases - January 7, 2021 Category: Neurology Authors: Luis A. Robles Tags: Case Report Source Type: research

Stroke Knowledge in the EstEPA Project, a Population-Based Study
Stroke knowledge is poor in the general population worldwide. Yet, data from Spanish-Speaking populations, particularly in Latin America, are scant. We aim to evaluate stroke awareness using personal interviews in a population-based study.
Source: Journal of Stroke and Cerebrovascular Diseases - November 24, 2020 Category: Neurology Authors: Maximiliano A Hawkes, Maia M Gomez-Schneider, Daiana E Dossi, Mario O Melcon, Sebasti án F Ameriso Source Type: research

Preoperatively estimated graft flow rate contributes to the improvement of hemodynamics in revascularization for Moyamoya disease
Moyamoya disease is a cerebrovascular disease that is characterized by chronic progressive stenosis of the terminal portion of the internal carotid artery (ICA) on both sides of the brain, which results in an abnormal vascular network of the collateral pathways at the base of the brain.1,2 Therefore, patients with Moyamoya disease have a decreased cerebral blood flow (CBF) and reduced cerebral perfusion pressure,3 which can result in ischemic and/or hemorrhagic stroke. This hemodynamic condition can be evaluated using positron emission tomography (PET) or single-photon emission computed tomography (SPECT) as the gold standard procedure.
Source: Journal of Stroke and Cerebrovascular Diseases - November 7, 2020 Category: Neurology Authors: Tomoyoshi Kuribara, Takeshi Mikami, Katsuya Komatsu, Yusuke Kimura, Sangnyon Kim, Kei Miyata, Yukinori Akiyama, Rei Enatsu, Toru Hirano, Nobuhiro Mikuni Source Type: research

D-dimer and Body CT to Identify Occult Malignancy in Acute Ischemic Stroke
Patients with acute ischemic stroke associated with cancer have D-dimer elevations greater than those with acute ischemic stroke or cancer alone. While D-dimer has been proposed as a screening tool to identify such patients, its use in clinical practice to identify malignancy and to inform the use of CT scanning has not been well characterized.
Source: Journal of Stroke and Cerebrovascular Diseases - October 8, 2020 Category: Neurology Authors: Jon Rosenberg, David Do, Brett Cucchiara, Steven R. Mess é Source Type: research

Rules About Rules – The 6-h CT Rule For Subarachnoid Hemorrhage
In this issue of the Journal of Stroke and Cerebrovascular Diseases, Chakraborty and colleagues describe the cautionary tale of a patient who presented with a thunderclap headache concerning for a subarachnoid hemorrhage (SAH). A head computed tomographic scan (CT) done 4  h after the onset of the headache was interpreted as negative but the patient was ultimately found to have an aneurysmal SAH.1
Source: Journal of Stroke and Cerebrovascular Diseases - September 15, 2020 Category: Neurology Authors: Jonathan A. Edlow Source Type: research

Spinal epidural hematoma as a stroke mimic
Spinal epidural hematoma is a rare disease with an annual incidence of 1 per 1,000,000 individuals;1 however, it is a critical stroke mimic.2 As patients with spinal epidural hematoma typically present with acute hemiparesis,3,4 such a presentation is not expected to be detected by a computed tomography (CT) scan of the brain, which is the most common neuroimaging choice in patients with an activated stroke code. Indeed, there are several case reports in which patients with spinal epidural hematoma were misdiagnosed with ischemic stroke and treated with anti-thrombotic therapy, including intravenous thrombolysis,5 –10 oc...
Source: Journal of Stroke and Cerebrovascular Diseases - August 15, 2020 Category: Neurology Authors: Yuichiro Inatomi, Makoto Nakajima, Toshiro Yonehara Source Type: research

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