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Pathologic Findings of Symptomatic Carotid Artery Stenosis Several Decades after Radiation Therapy: A Case Report
Improved long-term survival of malignancy has drawn increased attention to late cerebrovascular toxicity after neck radiotherapy. Recently, neck radiotherapy has been found as a significant risk factor of carotid artery stenosis and ischemic stroke; however, long-term adverse effects of radiation in large arteries remain unknown. Here, we described an autopsied case with recurrent ischemic stroke associated with ipsilateral carotid artery stenosis several decades after neck radiation therapy. Pathologically, there were intima-media fibrosis, endothelial cell loss, and decreased expression of thrombomodulin in irradiated ca...
Source: Journal of Stroke and Cerebrovascular Diseases - January 11, 2018 Category: Neurology Authors: Shuichi Tonomura, Keiji Shimada, Naoko Funatsu, Yoshiaki Kakehi, Hisao Shimizu, Nobuyuki Takahashi Tags: Case Studies Source Type: research

Moyamoya Disease Associated with Asymptomatic Mosaic Turner Syndrome: A Rare Cause of Hemorrhagic Stroke
We present the first reported case of an adult patient with previously unrecognized mosaic Turner syndrome with acute subarachnoid and intracerebral hemorrhage as the initial manifestation of moyamoya syndrome. A 52-year-old woman was admitted with a subarachnoid hemorrhage with associated flame-shaped intracerebral hemorrhage in the left frontal lobe. Physical examination revealed short stature, pectus excavatum, small fingers, micrognathia, and mild facial dysmorphism. Cerebral angiography showed features consistent with bilateral moyamoya disease, aberrant intrathoracic vessels, and an unruptured 4-mm right superior hyp...
Source: Journal of Stroke and Cerebrovascular Diseases - October 7, 2013 Category: Neurology Authors: Sunil Manjila, Benjamin R. Miller, Anitha Rao-Frisch, Balint Otvos, Anna Mitchell, Nicholas C. Bambakidis, Michael A. De Georgia Tags: Case Reports Source Type: research

A Reanalysis of Predictors for the Risk of Hemorrhage in Brain Arteriovenous Malformation
Brain arteriovenous malformation (BAVM) is a congenital cerebral vascular disease that characterized with intracranial hemorrhage and epilepsy. It has some risk in current treatments including microsurgery, endovascular, and radiation therapy. Some patients with bAVMs may keep unruptured in their whole life. Whether it should be treated depends on the evaluation of the hemorrhage risk of bAVM. Although previous studies gave many significant predictors, we tried to find some new and more significant predictors in 173 patients with bAVMS by retrospective analysis.
Source: Journal of Stroke and Cerebrovascular Diseases - April 2, 2018 Category: Neurology Authors: Zheng Huang, Kang Peng, Changqing Chen, Feiyue Zeng, Junyu Wang, Fenghua Chen Source Type: research

Left Thalamus Arteriovenous Malformation Secondary to Radiation Therapy of Original Vermian Arteriovenous Malformation: Case Report
A 70-year-old gentleman with history of hypothyroidism, hyperlipidemia, hypertension, and right superior cerebellar aneurysm presented to the neurosurgery service in 2008 with vertigo. Diagnostic cerebral angiography performed that year demonstrated a vermian arteriovenous malformations (AVM). The patient underwent stereotactic proton beam radiosurgery, which resulted in a decrease in flow and size of the lesion, and the patient was lost to follow-up. Now at the age of 80, the patient presented with acute gait instability.
Source: Journal of Stroke and Cerebrovascular Diseases - April 7, 2019 Category: Neurology Authors: Carlos Torres-Quinones, Matthew J. Koch, Scott B. Raymond, Aman Patel Tags: Case Report Source Type: research