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Balance of Symptomatic Pulmonary Embolism and Symptomatic Intracerebral Hemorrhage with Low-dose Anticoagulation in Recent Ischemic Stroke: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Conclusions: Prophylactic/low-dose heparin increased sICH by more than they reduced sPE in patients with recent ischemic stroke. Therefore, their routine acute use cannot be recommended, but they may still be relevant in patients at very high risk of PE (eg, morbid obesity, previous venous thromboembolism, and inherited thrombophilia) or if started later, although trials have not assessed these issues.
Source: Journal of Stroke and Cerebrovascular Diseases - April 19, 2012 Category: Neurology Authors: Chamila M. Geeganage, Nikola Sprigg, Matthew W. Bath, Philip M.W. Bath Tags: Original Articles Source Type: research

Risk of Carotid Stroke after Chiropractic Care: A Population-Based Case-Crossover Study
Chiropractic manipulation is a popular treatment for neck pain and headache, but may increase the risk of cervical artery dissection and stroke. Patients with carotid artery dissection can present with neck pain and/or headache before experiencing a stroke. These are common symptoms seen by both chiropractors and primary care physicians (PCPs). We aimed to assess the risk of carotid artery stroke after chiropractic care by comparing association between chiropractic and PCP visits and subsequent stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - November 20, 2016 Category: Neurology Authors: J. David Cassidy, Eleanor Boyle, Pierre C ôté, Sheilah Hogg-Johnson, Susan J. Bondy, Scott Haldeman Source Type: research

Cervical Artery Dissections with and without stroke, risk factors and prognosis: a Chilean prospective cohort
We aimed to characterize spontaneous cervical artery dissection (CeAD) patients with and without stroke and describe risk factors for cerebrovascular complications in a Chilean prospective cohort.Methods: Consecutive CeAD patients admitted to a Chilean center confirmed by neuroimaging. Logistic regression was used.Results: 168 patients were included, median follow-up time was 157 days. Stroke occurred in 49 (29.2%) cases, 4 (2%) patients died, all of whom had a stroke, and 10 (6%) presented CeAD recurrence.
Source: Journal of Stroke and Cerebrovascular Diseases - July 15, 2020 Category: Neurology Authors: E. Mazzon, D. Rocha, A.M. Brunser, C. De la Barra, X. Stecher, T. Bernstein, P. Z úñiga, V. Díaz, G. Martínez, P. Muñoz Venturelli Source Type: research

Case Misclassification in Studies of Spinal Manipulation and Arterial Dissection
Background: Spinal manipulation has been associated with cervical arterial dissection and stroke but a causal relationship has been questioned by population-based studies. Earlier studies identified cases using International Classification of Diseases Ninth Revision (ICD-9) codes specific to anatomic stroke location rather than stroke etiology. We hypothesize that case misclassification occurred in these previous studies and an underestimation of the strength of the association. We also predicted that case misclassification would differ by patient age.Methods: We identified cases in the Veterans Health Administration datab...
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2014 Category: Neurology Authors: Xuemei Cai, Ali Razmara, Jessica K. Paulus, Karen Switkowski, Pari J. Fariborz, Sergey D. Goryachev, Leonard D'Avolio, Edward Feldmann, David E. Thaler Tags: Original Articles Source Type: research

Vertebral Artery Dissection in Rheumatoid Arthritis with Cervical Spine Disease
A 59-year-old woman with long-standing active rheumatoid arthritis presented with posterior circulation ischemic stroke after vertebral dissection. She had severe multilevel degenerative changes of her cervical spine. She did not have classic stroke risk factors nor evidence of atherosclerotic disease or other systemic diseases. The most likely mechanism appears to be injury of the artery wall by an osteophyte, causing dissection that resulted in thrombosis and subsequent embolic strokes.
Source: Journal of Stroke and Cerebrovascular Diseases - January 25, 2013 Category: Neurology Authors: Ritika Mahajan, Branko N. Huisa Tags: Case Reports Source Type: research

Recanalization after Extracranial Dissection: Effect of Antiplatelet Compared with Anticoagulant Therapy
Cervical arterial dissection is a leading cause of stroke in young patients, yet optimal management remains controversial. Existing studies focusing on recurrent stroke were underpowered to demonstrate differences between antithrombotic strategies. Vessel recanalization is a more prevalent outcome and is potentially clinically important. We aimed to assess recanalization rates with anticoagulation compared with antiplatelet therapy.
Source: Journal of Stroke and Cerebrovascular Diseases - October 31, 2017 Category: Neurology Authors: Preethi Ramchand, Michael T. Mullen, Aaron Bress, Robert Hurst, Scott E. Kasner, Brett L. Cucchiara, Steven R. Mess é Source Type: research

Diagnosis of Spontaneous Cervical Artery Dissection May Be Associated with Increased Prevalence of Posttraumatic Stress Disorder
Background: Receiving information that one has a dissected cervical artery, which can cause a stroke at any time, is obviously traumatic, but details about the psychiatric and psychosocial sequelae are not known. We investigated the prevalence of and risk factors for posttraumatic stress disorder (PTSD) in patients with spontaneous cervical artery dissection (CD) and the impact of PTSD on their psychosocial functioning.Methods: Patients admitted because of CD between 2006 and 2010 were retrospectively examined using a diagnostic PTSD measure (Posttraumatic Diagnostic Scale). Patients between 2011 and 2012 were examined pro...
Source: Journal of Stroke and Cerebrovascular Diseases - July 12, 2013 Category: Neurology Authors: Verena Speck, Adam Noble, Rainer Kollmar, Thomas Schenk Tags: Original Articles Source Type: research

Compressive Cervical Radiculopathy due to Vertebral Artery Dissection
Rarely, not stroke but peripheral weakness can result from cervical artery dissection. In these cases, a mural hematoma compressing the ipsilateral C5 and/or C6 root can be demonstrated.
Source: Journal of Stroke and Cerebrovascular Diseases - March 24, 2015 Category: Neurology Authors: Olaf Eberhardt, Helge Topka Tags: Case Report Source Type: research

Spontaneous Bilateral Cervical Internal Carotid and Vertebral Artery Dissection in a Japanese Patient without Collagen Vascular Disease with Special Reference to Single-Nucleotide Polymorphisms
Spontaneous cervical artery dissection (sCAD) is a major cause of ischemic stroke in young adults. Frequently, sCAD involves multiple neck arteries, accounting for 13%-28% of the total sCAD cases. However, little is known about factors related to multiple sCAD. In this case, a 52-year-old man was admitted due to headache without aura. There was a personal history of migraine with aura and a family history of similar symptoms. The patient's younger brother had a left vertebral artery (VA) dissecting aneurysm and underwent endovascular occlusion of his parent artery at the age of 48.
Source: Journal of Stroke and Cerebrovascular Diseases - May 19, 2016 Category: Neurology Authors: Arata Abe, Chikako Nito, Yuki Sakamoto, Akane Nogami, Hiroyuki Hokama, Shiro Takahashi, Kumiko Kirita, Masayuki Ueda, Yoshiro Ishimaru, Kazumi Kimura Tags: Case Studies Source Type: research

Reversible Cerebral Vasoconstriction Syndrome and Dissection in the Setting of COVID-19 Infection
The current COVID-19 pandemic has recently brought to attention the myriad of neuro- logic sequelae associated with Coronavirus infection including the predilection for stroke, particularly in young patients. Reversible cerebral vasoconstriction syndrome (RCVS) is a well-described clinical syndrome leading to vasoconstriction in the intracra- nial vessels, and has been associated with convexity subarachnoid hemorrhage and oc- casionally cervical artery dissection. It is usually reported in the context of a trigger such as medications, recreational drugs, or the postpartum state; however, it has not been described in COVID-19 infection.
Source: Journal of Stroke and Cerebrovascular Diseases - June 4, 2020 Category: Neurology Authors: Katarina Dakay, Gurmeen Kaur, Edwin Gulko, Justin Santarelli, Christian Bowers, Stephan A Mayer, Chirag D Gandhi, Fawaz Al-Mufti Tags: Case Report Source Type: research

“COVID-19 and cervical artery dissection- A causative association?”
COVID-19 is a pandemic disease which predominantly affects the respiratory system, however it also causes multi-organ dysfunction in a subset of patients. There is a growing evidence that it increases the propensity of strokes in younger patients. Besides producing a prothrombotic state, arterial dissection could be one of its many manifestations, increasing the risks of stroke. Herein, we report the first case of spontaneous bilateral vertebral artery dissection in a patient with COVID-19. 39-year female presented with spontaneous bilateral vertebral artery dissections without any instigating traumatic events and no histo...
Source: Journal of Stroke and Cerebrovascular Diseases - June 12, 2020 Category: Neurology Authors: Pratit Patel, Priyank Khandelwal, Gaurav Gupta, Amit Singla Source Type: research

Cervical Artery Dissection Caused by Electrical Cupping Therapy with High-Negative Pressure – Case Report
Cervical artery dissection is an important cause of stroke in the young. The etiology is still discussed controversial. The most obvious reason for a dissection of extracranial arteries is due to a trauma, eg. after car accidents or other high speed traumas such as high-velocity road traffic accidents. Besides these clear cases, chiropractic neck maneuvers represent potential reasons for vessel injuries. Case presentation: We here report a rare case of secondary cervical artery dissection after so-called cupping therapy and a preventive treatment with a direct oral anticoagulant.
Source: Journal of Stroke and Cerebrovascular Diseases - August 17, 2020 Category: Neurology Authors: Fr édéric Zuhorn, Wolf-Rüdiger Schäbitz, Christian Oelschläger, Randolf Klingebiel, Andreas Rogalewski Tags: Case Report Source Type: research

Influenza-Like Illness is Associated with Increased Short-Term Risk of Cervical Artery Dissection
Non-traumatic Cervical Artery Dissection (CeAD) is a leading cause of ischemic stroke in the young. Influenza-like illnesses (ILI) trigger ischemic strokes. We hypothesized that influenza and ILI are associated with CeAD.
Source: Journal of Stroke and Cerebrovascular Diseases - November 27, 2020 Category: Neurology Authors: Madeleine D. Hunter, Yeseon P. Moon, Eliza C. Miller, Erin R. Kulick, Amelia K. Boehme, Mitchell SV Elkind Source Type: research

Vertebral Artery Tortuosity and Morphometric Characteristics of Patients with Recurrent Cervical Artery Dissection
Cervical Artery Dissection is an important cause of stroke in the young. Data on incidence and associations of recurrence in patients with cervical artery dissection are lacking. Increased Vertebral Artery Tortuosity Index has been reported in patients with cervical artery dissection and associated with earlier age of arterial dissection in patients with connective tissue disease.
Source: Journal of Stroke and Cerebrovascular Diseases - February 19, 2022 Category: Neurology Authors: JA Narrett, CM Aldridge, J Garrett, B Abdalla, J Donahue, BB Worrall, AM Southerland Tags: Short Communication Source Type: research

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