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Source: Journal of Stroke and Cerebrovascular Diseases
Nutrition: Calcium
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Total 20 results found since Jan 2013.
Epidemiology, Pathophysiology, and Treatment of Hypertension in Ischaemic Stroke Patients
Stroke continues to be one of the leading causes of mortality and morbidity worldwide. There are 2 main types of stroke: ischaemic strokes, which are caused by obstruction of the blood vessels leading to or within the brain, and haemorrhagic strokes, which are induced by the disruption of blood vessels. Stroke is a disease of multifactorial aetiology that may develop as an end state in patients with serious vascular conditions—most notably, uncontrolled arterial hypertension—thereby necessitating the effective control of this risk factor to prevent stroke or its recurrence. This paper focuses specifically on the epidem...
Source: Journal of Stroke and Cerebrovascular Diseases - June 11, 2012 Category: Neurology Authors: Nur Fatirul Hisham, Ulvi Bayraktutan Tags: Review Articles Source Type: research
Factors Influencing Quality of Life in Stroke Patients: Focus on Eating Habits
This study aimed to identify lifestyle factors about eating habits that may affect the quality of life (QOL) in elderly stroke patients. Methods: Fifty elderly patients with a first-ever stroke were enrolled. QOL was assessed by the Stroke and Aphasia QOL Scale-39-J. Lifestyle factors about eating habits were collected using questionnaires (Questions 1-17) for the intake of salt, calcium, magnesium, potassium, taurine, fiber, and protein, and the frequency of breakfast.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2019 Category: Neurology Authors: Reina Chiba, Saya Tominaga, Kasumi Mikami, Maiko Kitajima, Mayumi Urushizaka, Toshiko Tomisawa, Junko Chiba, Joji Hagii, Minoru Yasujima, Tomohiro Osanai Source Type: research
Calcium Channel Subunit α2δ-1 as a Potential Biomarker Reflecting Illness Severity and Neuroinflammation in Patients with Acute Ischemic Stroke
Cerebral infarction (commonly known as ischemic stroke) is a leading cause of morbidity, mortality and disability worldwide. Activation of presynaptic voltage-gated calcium channels (VGCCs) and glutamate release plays a central role in neuronal necrosis after cerebral ischemia.1,2 Previous studies seemed to be encouraging that nimodipine, a dihydropyridine calcium channel antagonist, had a significant benefit in mortality and neurologic outcome in patients with mild stroke or within 12 hours of stroke, although there was still controversial.
Source: Journal of Stroke and Cerebrovascular Diseases - May 25, 2021 Category: Neurology Authors: Xiaoqin Xiong, Linjing Zhang, Yunhui Li, Shuang Guo, Wei Chen, Lijun Huang, Yi Luo Source Type: research
Intracranial Artery Calcium Burden Predicts Recurrent Cerebrovascular Events in Transient Ischaemic Attack Patients
Background: Patients with initial transient ischaemic attack (TIA) subsequently have a higher risk of recurrent TIA or acute ischemic stroke (AIS). The role of scoring intracranial arterial calcification (IAC) in predicting the prevalence of stroke remains unclear. We aim to evaluate if radiological CT calcium score measuring IAC burden could predict future ischemic events in a cohort of TIA patients. Methods: We studied consecutive patients from July 2014 to December 2015 who presented with first episode of TIA.
Source: Journal of Stroke and Cerebrovascular Diseases - June 13, 2019 Category: Neurology Authors: Wan Yee Kong, Benjamin YQ Tan, Eide Sterling Ellis, Nicholas JH Ngiam, Wilson GW Goh, Vijay K Sharma, Bernard PL Chan, Leonard LL Yeo Source Type: research
Surgical Treatment for Carotid Stenoses with Highly Calcified Plaques
Background: The aim of this study was to clarify both the present status of treatment for carotid stenosis with highly calcified plaques and the appropriate treatment.Methods: A total of 140 consecutive treatments for carotid stenoses (carotid endarterectomy [CEA]:carotid artery stenting [CAS] 81:59) were enrolled in the study. We classified the patients into low-calcified plaque (LCP) and high-calcified plaque (HCP) groups by calcium score, determined by a receiver operating characteristic analysis, and we compared the results after both treatments.Results: The mean degree of residual stenosis and improvement rates of the...
Source: Journal of Stroke and Cerebrovascular Diseases - December 27, 2012 Category: Neurology Authors: Hiroyuki Katano, Mitsuhito Mase, Yusuke Nishikawa, Kazuo Yamada Tags: Original Articles Source Type: research
Telmisartan Ameliorates Inflammatory Responses in SHR-SR After tMCAO
We examined the effects of telmisartan on inflammatory responses of monocyte chemotactic protein-1, tumor necrosis factor-α, and ionized calcium-binding adapter molecule 1 in the brain of spontaneously hypertensive rat stroke-resistant (SHR-SR) after transient middle cerebral artery occlusion (tMCAO).
Source: Journal of Stroke and Cerebrovascular Diseases - September 20, 2014 Category: Neurology Authors: Kota Sato, Toru Yamashita, Tomoko Kurata, Yusuke Fukui, Nozomi Hishikawa, Kentaro Deguchi, Koji Abe Source Type: research
Influence of Experimental Subarachnoid Hemorrhage on Nicotine-induced Contraction of the Rat Basilar Artery in Relation to Nicotinic Acetylcholine Receptors, Calcium, and Potassium Channels
Conclusions: Nicotine-induced contraction of the rat basilar artery involved the CNS nAChR subfamily, skeletal muscle nAChR subfamily, and L-type Ca2+ channel pathways. SAH did not affect any of the subfamilies of nAChR, but the Ca2+ channel was reduced and the adenosine triphosphate–sensitive K+ channel was enhanced by SAH.
Source: Journal of Stroke and Cerebrovascular Diseases - November 4, 2011 Category: Neurology Authors: Xu Ji, Aimin Wang, Cristina C. Trandafir, Kazuyoshi Kurahashi Tags: Original Articles Source Type: research
Influence of Experimental Subarachnoid Hemorrhage on Nicotine-induced Contraction of the Rat Basilar Artery in Relation to Arachidonic Acid Metabolites Signaling Pathway
Conclusions: One week after exposure to SAH, PLC, sPLA2, and COX-2 activity were enhanced and cPLA2 activity was inhibited. One hour after exposure to SAH, PLC activity was enhanced and cPLA2 and iPLA2 activity was inhibited. Such changes of inflammatory arachidonic acid metabolites by smoking after SAH may play important roles in fatal cerebral circulatory disorders, suggesting important implications for the etiology and pathogenesis of SAH.
Source: Journal of Stroke and Cerebrovascular Diseases - January 3, 2012 Category: Neurology Authors: Xu Ji, Aimin Wang, Cristina C. Trandafir, Kazuyoshi Kurahashi Tags: Original Articles Source Type: research
The Effect of Mitochondrial Calcium Uniporter Opener Spermine on Diazoxide against Focal Cerebral Ischemia—Reperfusion Injury in Rats
Conclusions: Our results suggested that diazoxide, which improved neurological deficits and decreased infarct volume and oxidative stress against ischemia–reperfusion injury, is mediated by spermine.
Source: Journal of Stroke and Cerebrovascular Diseases - March 28, 2013 Category: Neurology Authors: Huanli Dong, Shilei Wang, Zongwang Zhang, Ailan Yu, Zhong Liu Tags: Original Articles Source Type: research
Mitochondrial Calcium Uniporter Opener Spermine Attenuates the Cerebral Protection of Diazoxide through Apoptosis in Rats
Conclusions: Results in our study suggested that diazoxide improved neurologic deficits, decreased infarct volume in cortex but not in subcortex, and apoptosis in cortex against ischemia/reperfusion injury is mediated by spermine.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2013 Category: Neurology Authors: Lei Zhang, Xiujuan Gao, Xin Yuan, Huanli Dong, Zongwang Zhang, Shilei Wang Tags: Original Articles Source Type: research
Upregulation of ANGPTL4 Messenger RNA and Protein in Severely Calcified Carotid Plaques
Conclusions: In high-calcified plaques, ANGPTL4 might be upregulated for antiangiogenic modulating function together with the downregulation of FGFR2, contributing to the stability of the plaques.
Source: Journal of Stroke and Cerebrovascular Diseases - September 30, 2013 Category: Neurology Authors: Hiroyuki Katano, Kazuo Yamada Tags: Original Articles Source Type: research
Recurrent Extracranial Internal Carotid Artery Vasospasm Diagnosed by Serial Magnetic Resonance Angiography and Superselective Transarterial Injection of a Calcium Channel Blocker
In conclusion, we recommend intensive radiologic follow-up at the acute stage and therapeutic catheter angiography when the bilateral lesion is evident because bilateral occlusion of the ICA could lead to a catastrophic condition.
Source: Journal of Stroke and Cerebrovascular Diseases - March 21, 2014 Category: Neurology Authors: Yoshiteru Shimoda, Miki Fujimura, Naoto Kimura, Masayuki Ezura, Hiroshi Uenohara, Teiji Tominaga Tags: Case Reports Source Type: research
Calcified Carotid Plaques Show Double Symptomatic Peaks According to Agatston Calcium Score
The precise mechanism of carotid calcification formation and its clinical significance including the difference in outcomes compared with coronary artery have not been clearly elucidated yet. We applied the calcium score for analyzing carotid plaque calcification in focus on its relationship with symptoms and discuss the difference in transitional patterns and the clinical outcome in comparison with calcified coronary plaques.
Source: Journal of Stroke and Cerebrovascular Diseases - March 24, 2015 Category: Neurology Authors: Hiroyuki Katano, Mitsuhito Mase, Yusuke Nishikawa, Kazuo Yamada Source Type: research
The Possible Damaged Mechanism and the Preventive Effect of Monosialotetrahexosylganglioside in a Rat Model of Cerebral Ischemia-Reperfusion Injury
The pathogenesis of cerebral ischemia-reperfusion injury (CIRI) is not completely clear and therapies are limited now. Therefore, our study aimed to investigate the possible pathogenesis and preventive approach of CIRI through analyzing changes of aspartate (Asp), glutamate (Glu), mitochondrial calcium (MCa), calmodulin (CaM), and malondialdehyde (MDA) contents and ultramicropathology in hippocampus and cerebral cortex of ischemic susceptible injured regions and the effect of monosialotetrahexosylganglioside (GM1) in the rat model of CIRI.
Source: Journal of Stroke and Cerebrovascular Diseases - April 28, 2015 Category: Neurology Authors: Jie Zhang, Xin Fang, Yiyi Zhou, Xia Deng, Yi Lu, Jiao Li, Shujuan Li, Bo Wang, Renshi Xu Source Type: research
Evaluation of the Differences in the Effects of Antihypertensive Drugs on Blood Pressure Variability by 24-Hour Ambulatory Blood Pressure Monitoring in Chronic Cerebrovascular Disease
It has been suggested that antihypertensive drug therapy is attributable to the lower blood pressure variability, we investigated the effects of 4 classes of antihypertensives on the blood pressure variability; in addition, we also compared the effects among 4 calcium channel blockers.
Source: Journal of Stroke and Cerebrovascular Diseases - May 13, 2015 Category: Neurology Authors: Ryoji Nishioka, Shunsuke Kinoshita, Michio Shiibashi, Tomokazu Shimazu, Yoshihiko Nakazato, Toshimasa Yamamoto, Naotoshi Tamura, Nobuo Araki Source Type: research
