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Endovascular Therapy is Effective for Large Vessel Occlusion Despite Concurrent Cancer
Ischemic stroke and concurrent cancer is increasingly recognized. However, optimal management is uncertain. As mechanical thrombectomy has become the standard of care for large vessel occlusion, more patients with cancer are presenting for embolectomy. However, it is unknown whether this subgroup has the same benefit profile described in multiple randomized trials for thrombectomy for large vessel occlusion. Our objective was to retrospectively evaluate a North American embolectomy database for safety and outcomes in patients with active cancer.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2022 Category: Neurology Authors: Thomas K. Mattingly, Jorge E. Risco, Jaclyn E. Burch, Raquel Whyte, Gurkirat S. Kohli, Stephen Susa, Tarun Bhalla, Matthew T. Bender Source Type: research

Intra-arterial thrombolysis as adjunct to mechanical thrombectomy in acute ischemic stroke patients in the United States: A case control analysis
Although observational studies have reported favorable clinical outcomes associated with intra-arterial thrombolysis as adjunct to mechanical thrombectomy, the cost and length of hospitalization associated with this intervention has not been studied.
Source: Journal of Stroke and Cerebrovascular Diseases - May 5, 2023 Category: Neurology Authors: Chun Shing Kwok, Navpreet K. Bains, Daniel E. Ford, Camilo R. Gomez, Daniel F. Hanley, Ameer E. Hassan, Thanh N. Nguyen, Farhan Siddiq, Alejandro M. Spiotta, Syed F. Zaidi, Adnan I. Qureshi Source Type: research

Postapproval Community Hospital Experience in the United States with Left Atrial Appendage Closure Device (Watchman)
To review the procedural safety and postimplantation complications of Watchman device implanted at 2 community hospitals for primary prevention of systemic embolization in patients with nonvalvular atrial fibrillation (NVAF) who were not candidates for long-term oral anticoagulation (OAC).
Source: Journal of Stroke and Cerebrovascular Diseases - May 29, 2018 Category: Neurology Authors: Koroush Khalighi, Munish Sharma, Rohit Masih, Vadim Levin Source Type: research

Racial Difference in Cerebral Microbleed Burden Among a Patient Population in the Mid-South United States
Although intracerebral hemorrhage (ICH) is more common among African-Americans, data on the burden of cerebral microbleeds (CMBs) among different races is limited. The purpose of this study is to compare the number, associated factors, and topography of CMBs between African-American and Caucasian populations in the Mid-South United States.
Source: Journal of Stroke and Cerebrovascular Diseases - June 23, 2018 Category: Neurology Authors: Nariman Noorbakhsh-Sabet, Georgios Tsivgoulis, Shima Shahjouei, Yirui Hu, Nitin Goyal, Andrei V. Alexandrov, Ramin Zand Source Type: research

Pre-Existing Renal Failure Increases In-Hospital Mortality in Patients with Intracerebral Hemorrhage
To determine the clinical outcome for intracerebral hemorrhage (ICH) patients with pre-existing renal failure in the United States.
Source: Journal of Stroke and Cerebrovascular Diseases - November 14, 2018 Category: Neurology Authors: Rakesh Khatri, Mohammad Rauf Afzal, Mohtashim Arbaab Qureshi, Alberto Maud, Dou Huanyu, Gustavo Jose Rodriguez Source Type: research

Endovascular Thrombolysis or Thrombectomy for Cerebral Venous Thrombosis: Study of Nationwide Inpatient Sample 2004-2014
In this study, we analyze Nationwide Inpatient Sample (NIS) data to evaluate the safety and efficacy of endovascular therapy (ET) versus medical management in CVT. We also examined the yearly trends of ET utilization in the United States. Methods: International Classification of Diseases, Ninth Revision, Clinical Modification codes were utilized to identify CVT patients who received ET.
Source: Journal of Stroke and Cerebrovascular Diseases - April 1, 2019 Category: Neurology Authors: Fazeel M. Siddiqui, Matthew W. Weber, Sudeepta Dandapat, Steve Scaife, Michael Buhnerkempe, Santiago Ortega-Gutierrez, Nazan Aksan, Augusto Elias, Jonathan M. Coutinho Source Type: research

Recent Trends in Electively Treated Unruptured Intracranial Aneurysms
Background and Purpose: To determine recent treatment and outcome trends in patients undergoing elective surgical clipping (SC) or endovascular therapy (EVT) for unruptured intracranial aneurysms (UIAs) in the United States. Methods: Data were extracted and analyzed from the National Inpatient Sample, Healthcare Cost and Utilization Project, Agency for Healthcare Research and Quality for all patients admitted for elective EVT or SC of UIAs between 2011 and 2014. Treatment trends, in-hospital mortality, complication rates, length of stay (LOS) and total hospital costs were evaluated and analyzed.
Source: Journal of Stroke and Cerebrovascular Diseases - April 10, 2019 Category: Neurology Authors: Hisham Salahuddin, Nauman Siddiqui, Alicia C. Castonguay, Mark Johnson, Syed F. Zaidi, Mouhammad A. Jumaa Source Type: research

Pre-existing Renal Failure Increases In-Hospital Mortality in Patients With Intracerebral Hemorrhage
We read with interest the study of Khatri et al that concluded pre-existing renal failure increased the risk of in-hospital mortality among patients with intracerebral hemorrhage (ICH).1 These results were derived from a retrospective analysis of over 328,000 adult patients (11.8% with pre-existing renal failure) who were admitted to hospitals in the United States with ICH over a 5-year period.
Source: Journal of Stroke and Cerebrovascular Diseases - May 22, 2019 Category: Neurology Authors: Ruemon Bhattacharyya, Larry E. Miller Tags: Letter to the Editor Source Type: research

Asian Study of Cerebral Venous Thrombosis
The objective of the present study is to identify risk factors, presentation, and outcome of CVT in Asian patients. Methods: Asian CVT registry is a prospective multinational observational study that included patients (aged> 16 years) with symptomatic CVT. Results: Eight hundred and twelve patients (59% women) from 20 centers in 9 Asian countries were included.
Source: Journal of Stroke and Cerebrovascular Diseases - July 23, 2019 Category: Neurology Authors: Mohammad Wasay, Subash Kaul, Bindu Menon, Alper I. Dai, Mohammad Saadatnia, Abdul Malik, Ahmed Khalifa, Afshin Borhani-Haghigi, Manmohan Mehndiratta, Maria Khan, Nimalendu Bikash Bhowmik, Safia Awan Source Type: research

Older Age Is Not Associated with Worse Outcomes Following Decompressive Hemicraniectomy for Spontaneous Intracerebral Hemorrhage
Background: Decompressive hemicraniectomy (DHC) is commonly offered after large spontaneous intracerebral hemorrhage (ICH) as a life-saving measure. Based on limited available evidence, surgery is sometimes avoided in the elderly. The association between age and outcomes following DHC in spontaneous ICH remains largely understudied. Objective: The goal of this study is to investigate the influence of older age on outcomes of patients who undergo DHC for spontaneous ICH. Methods: In this retrospective cohort study, inpatient data were obtained from the United States Nationwide Inpatient Sample from 2000 to 2011.
Source: Journal of Stroke and Cerebrovascular Diseases - August 4, 2019 Category: Neurology Authors: Roy A. Poblete, Ling Zheng, Marcela Arenas, Alejandro Vazquez, Derek Yu, Benjamin A. Emanuel, May A. Kim-Tenser, Nerses Sanossian, William Mack Source Type: research

Factors Associated with Inpatient Mortality after Intracerebral Hemorrhage: Updated Information from the United States Nationwide Inpatient Sample
Background: To use a nationwide database of hospital admissions to assess for trends in inpatient mortality from acute spontaneous intracerebral hemorrhage as well as associated potentially contributing factors. Methods: Adults with intracerebral hemorrhage in the US National Inpatient Sample database from 2012 to 2015 were included in this study. We assessed for mortality rate as well as potential impact of various comorbidities and demographic factors such as ethnicity and median house hold income on inpatient mortality rate.
Source: Journal of Stroke and Cerebrovascular Diseases - December 18, 2019 Category: Neurology Authors: Vijayakumar Javalkar, Okkes Kuybu, Debra Davis, Roger E. Kelley Source Type: research

The interplay between COVID 19 and non-communicable diseases
Since the coronavirus designated as COVID-19 emerged as a global pathogen in late 2019, there has been rapid spread across the globe. After originating in China, several high-income countries such as Italy, Spain, United States, and the United Kingdom have had high case prevalence and high levels of mortality.
Source: Journal of Stroke and Cerebrovascular Diseases - June 30, 2020 Category: Neurology Authors: Seemant Chaturvedi, Philip Gorelick Source Type: research

In defense of our patients: indirect negative neurological consequences of sars-cov-2 in the new york epicenter
New York has become the epicenter in the United States for the coronavirus disease 2019 (COVID-19) pandemic with approximately 202,829 infected, 52,697 hospitalized, and 17,055 confirmed deaths as of June 5, 2020.15 The large influx of critically ill patients resulted in widespread policy and practice changes to counter this new resource-limited setting. All elective surgeries were cancelled. Urgent cases required approval and were limited significantly, resulting in primarily emergency cases.
Source: Journal of Stroke and Cerebrovascular Diseases - July 9, 2020 Category: Neurology Authors: Jared B. Cooper, Anubhav G. Amin, Michael G. Kim, Alan A. Stein, Jose Dominguez, Krishna Amuluru, Rachana Tyagi, Stephan Mayer, Chirag D. Gandhi, Fawaz Al-Mufti Source Type: research

Transient Ischemic Attack: The Trend and Readmissions in the United States
: Transient ischemic attack (TIA) is a temporary event of neurological dysfunction. Patients with TIA may be discharged from the Emergency Department or following an observational admission since their symptoms have resolved. Some portion of these patients, however, return to the hospital due to various reasons. The aim of our study is to find the trend of TIA readmissions in the United States.
Source: Journal of Stroke and Cerebrovascular Diseases - July 15, 2020 Category: Neurology Authors: Jared Alexander Stowers, Tiffany Brown, Lee Albert Birnbaum, Ali Seifi Source Type: research

Impact of Ruptured Aneurysm Circulation on Mortality: A Nationwide Inpatient Sample Analysis
This study investigates the effect of aneurysm circulation on mortality and patient outcomes after aneurysmal subarachnoid hemorrhage (SAH) within the United States.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Anand Dharia, John V. Lacci, Justin Mascitelli, Ali Seifi Source Type: research

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