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Methods and early recruitment of the Brain Attack Surveillance in Corpus Christi —Post-acute Care (BASIC-PAC) Project
Mexican Americans (MAs) are the most numerous sub-group of Latinx, the largest minority population in the United States. This important sub-group is aging and growing rapidly. Stroke incidence is similar in MAs compared with non-Hispanic whites (NHWs),1 and MA stroke survivors have worse neurologic, functional, cognitive and quality of life outcomes at 90-days post-stroke compared with NHWs for reasons that are not completely understood.2 Worse stroke outcomes in MAs are not fully explained by socio-demographics, including education and insurance, stroke treatment, stroke severity or subtype, or pre-stroke factors.
Source: Journal of Stroke and Cerebrovascular Diseases - November 3, 2022 Category: Neurology Authors: Lewis B. Morgenstern, Elizabeth M. Almendarez, Roshanak Mehdipanah, Madeline Kwicklis, Erin Case, Melinda A. Smith, Lynda D. Lisabeth Source Type: research

Program to Avoid Cerebrovascular Events through Systematic Electronic Tracking and Tailoring of an Eminent Risk factor: Protocol of a RCT
Geographical and racial disparities in stroke outcomes are especially prominent in the Southeastern United States, which represents a region more heavily burdened with stroke compared to the rest of the country. While stroke is eminently preventable, particularly via blood pressure control, fewer than one third of patients with a stroke have their blood pressure controlled ≥ 75% of the time, and low consistency of blood pressure control is linked to higher stroke risk.
Source: Journal of Stroke and Cerebrovascular Diseases - May 27, 2021 Category: Neurology Authors: Ashley M. Wabnitz, Jessica Chandler, Frank Treiber, Souvik Sen, Carolyn Jenkins, Jill C. Newman, Martina Mueller, Ariana Tinker, Amelia Flynn, Raelle Tagge, Bruce Ovbiagele Source Type: research

Treatment with Uric Acid Reduces Infarct and Improves Neurologic Function in Female Mice After Transient Cerebral Ischemia
Exogenous administration of uric acid, a naturally occurring antioxidant that scavenges reactive oxygen species in vasculature, has shown protective efficacy in both rodent models of stroke and human stroke patients in Spain as an adjuvant treatment to mechanical thrombectomy. Before clinical trials can be initiated in the United States, however, confirmation of efficacy in alternative preclinical models is required in accordance with stroke therapy academic industry roundtable-RIGOR criteria. To date, preclinical efficacy has only been established in the acute setting in male rodents.
Source: Journal of Stroke and Cerebrovascular Diseases - February 3, 2018 Category: Neurology Authors: Nirav Dhanesha, Edwin V ázquez-Rosa, Coral J. Cintrón-Pérez, Daniel Thedens, Alexa J. Kort, Vicky Chuong, Adriana M. Rivera-Dompenciel, Anil K. Chauhan, Enrique C. Leira, Andrew A. Pieper Source Type: research

The Effect of a County Prehospital FAST-ED Initiative on Endovascular Treatment Times
Stroke is the fifth leading cause of death in the United States, with approximately 140,000 deaths per year, and a cost of $34 billion per year.1 The most severe strokes are caused by large vessel occlusions (LVOs) which benefit the most from timely endovascular thrombectomy. In the US this therapy is reliably available only at thrombectomy-capable and comprehensive stroke centers (TSCs and CSCs, respectively).2 It is therefore important that patients with LVO stroke are identified promptly as such and triaged appropriately to the right facility type.
Source: Journal of Stroke and Cerebrovascular Diseases - August 13, 2020 Category: Neurology Authors: Helen Rynor, Jake Levine, Joseph Souchak, Ned Shashoua, Maygret Ramirez, Ivis C. Gonzalez, Virginia Ramos, Anshul Saxena, Emir Veledar, Amy K. Starosciak, Felipe De Los Rios La Rosa Source Type: research

Endovascular Treatment Decision Making in Patients with Low Baseline ASPECTS: Insights from UNMASK EVT, an International Multidisciplinary Study
Endovascular therapy is a highly effective treatment for acute ischemic stroke (AIS) due to large vessel occlusion (LVO)1 and now considered standard of care.2 In most randomized EVT trials, patients with low Alberta Stroke Program Early CT Score (ASPECTS) scores were either excluded or underrepresented. Hence, current European and North American guidelines for the early management of patients with acute ischemic stroke restrict level 1A recommendations for endovascular therapy (EVT) to patients with baseline ASPECTS score>5.
Source: Journal of Stroke and Cerebrovascular Diseases - October 29, 2020 Category: Neurology Authors: Johanna Maria Ospel, Ravinder Singh, Nima Kashani, Mohammed Almekhlafi, Alexis Wilson, Urs Fischer, Bruce Campbell, Shinichi Yoshimura, Francis Turjman, Pillai Sylaja, Ji-Hoe Heo, Michael D. Hill, Gustavo Saposnik, Mayank Goyal, Bijoy Menon Source Type: research

Evaluation of the Rapid Arterial oCclusion Evaluation (RACE) scale in Upstate South Carolina, USA
This study was designed to determine if the Rapid Arterial oCclusion Evaluation scale is a valid prehospital stroke assessment for identifying large vessel occlusion patients in South Carolina, USA.
Source: Journal of Stroke and Cerebrovascular Diseases - September 8, 2022 Category: Neurology Authors: Samadhi Thavarajah, Zachary Langston, Adam Sarayusa, Lauren A. Fowler, Sanjeev Sivakumar, Neel Shah Source Type: research

Malignant Cerebral Ischemia in A COVID-19 Infected Patient: Case Review and Histopathological Findings
Severe acute respiratory syndrome coronavirus (SARS-CoV-2) is responsible for an unprecedented worldwide pandemic that has severely impacted the United States. As the pandemic continues, a growing body of evidence suggests that infected patients may develop significant coagulopathy with resultant thromboembolic complications including deep vein thrombosis, pulmonary embolism, myocardial infarction, and ischemic stroke. However, this data is limited and comes from recent small case series and observational studies on stroke types, mechanisms, and outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - August 4, 2020 Category: Neurology Authors: Smit D. Patel, Ryan Kollar, Patrick Troy, Xianyuan Song, Mohammad Khaled, Augusto Parra, Mubashir Pervez Source Type: research

Corrigendum to ‘Health Behaviors among Stroke Survivors in the United States: A Propensity Score-Matched Study’ Journal of Stroke & Cerebrovascular Diseases, Vol. 27, No. 8 (August), 2018: pp 2124 –2133
The authors regret to inform the readers that there was an unnoticed mistake in the paper. An affiliation of Dr. Wali was not listed at the time of publication due to an oversight from the author. The aforementioned missing affiliation is the following: Department of Pharmacy Practice, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia.
Source: Journal of Stroke and Cerebrovascular Diseases - February 9, 2021 Category: Neurology Authors: Haytham Wali, Sawsan Kurdi, Jawad Bilal, Irbaz Bin Riaz, Sandipan Bhattacharjee Tags: Corrigendum Source Type: research

Hemicraniectomy for Malignant Middle Cerebral Artery Syndrome: A Review of Functional Outcomes in Two High-Volume Stroke Centers
Despite recent landmark randomized controlled trials showing significant benefits for hemicraniectomy (HCT) compared with medical therapy (MT) in patients with malignant middle cerebral artery infarction (MMCAI), HCT rates have not substantially increased in the United States. We sought to evaluate early outcomes in patients with MMCAI who were treated with HCT (cases) in comparison to patients treated with MT due to the perception of procedural futility by families (controls).
Source: Journal of Stroke and Cerebrovascular Diseases - May 15, 2018 Category: Neurology Authors: Abhi Pandhi, Georgios Tsivgoulis, Nitin Goyal, Muhammad F. Ishfaq, Shailesh Male, Efstathios Boviatsis, Jason J. Chang, Ramin Zand, Konstantinos Voumvourakis, Lucas Elijovich, Anne W. Alexandrov, Marc D. Malkoff, Daniel Hoit, Adam S. Arthur, Andrei V. Ale Source Type: research

Hospital Quality Metrics: “America's Best Hospitals” and Outcomes After Ischemic Stroke
Background: Developing quality metrics to assess hospital-level care and outcomes is increasingly popular in the United States. The U.S. News& World Report ranking of “America's Best Hospitals” is an existing, popular hospital-profiling system, but it is unknown whether top-ranked hospitals in their report have better outcomes according to other hospital quality metrics such as the Centers for Medicare and Medicaid Services (CMS) publicly reported 30-day stro ke measures. Methods: The analysis was based on the 2015-2016 U.S.
Source: Journal of Stroke and Cerebrovascular Diseases - November 8, 2018 Category: Neurology Authors: Judith H. Lichtman, Erica C. Leifheit, Yun Wang, Larry B. Goldstein Source Type: research

Impact of Race-Ethnic and Economic Disparities on Rates of Vascular Dementia in the National Inpatient Sample Database from 2006-2014
We have previously reported regional differences in the rates of vascular dementia (VD) in the United States (US), with the West having lower rates of VD diagnosis found in the Healthcare Cost and Utilization Project Nationwide Inpatient Sample (NIS) Database. We aimed to determine if these regional differences were associated with race-ethnic disparities in economic status or prevalence of the stroke risk factors hypertension, diabetes, and hyperlipidemia.
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Alexis Netis Simpkins Tags: Poster 10 Source Type: research

Timing of Recognition for Perioperative Strokes Following Cardiac Surgery
Cerebrovascular disease represents one of the largest burdens to mortality, morbidity, and healthcare associated costs both in the United States and globally.1 –3 While prevention should be the primary strategy especially in patients with stroke risk factors, early recognition of strokes provides opportunity for revascularization that limits morbidity and mortality.4 Paradoxically, strokes that occur during hospitalizations have been shown to result in l ower rates of early detection, increased wait times to intervention, and poorer overall outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - September 29, 2020 Category: Neurology Authors: Beret Amundson, Joseph Hormes, Anna Katema, Priyadharshi Rathakrishnan, J. Kirk Edwards, Gregory Esper, Jose Binongo, Yi Lasanajak, Brent Keeling, Michael Halkos, Fadi Nahab Source Type: research

Racial Disparities in Ischemic Stroke among Patients with COVID-19 in the United States
Cerebrovascular prevalence is high in patients with coronavirus disease 2019 (COVID-19). However, whether racial disparities exist among this population have not been systematically explored.
Source: Journal of Stroke and Cerebrovascular Diseases - May 18, 2021 Category: Neurology Authors: Alain Lekoubou, Matt Pelton, Djibril M. Ba, Addy Ssentongo Source Type: research

Discovery of Anti-SS-A Antibodies during Stroke Investigations in Young Adults: What Impact?
Approximately 10 to 14% of ischemic strokes (IS) occur in young adults.1,2 It is a relatively rare event but several international studies have recently demonstrated a rising incidence in this population.3 –6 In the United States,4 the rate of strokes in the 35- to 39-year age group increased from 9.5 strokes per 100,000 person-years in 1995–1999 to 23.6 strokes per 100,000 person-years in 2010–2014 (risk ratio 2.47; 95% CI, 2.07–2.96 [p 
Source: Journal of Stroke and Cerebrovascular Diseases - June 15, 2021 Category: Neurology Authors: Soledad Henriquez, Nicolas Legris, Pascale Chr étien, Salima Hacein-Bey-Abina, Julien Henry, Christian Denier, Nicolas Noël Source Type: research

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