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Thrombectomy for Stroke at 6-24 hours without Perfusion CT Software for Patient Selection
This study aimed to elucidate the efficacy of thrombectomy 6-24 hours after onset in our patient cohort using conventional imaging mismatch.
Source: Journal of Stroke and Cerebrovascular Diseases - December 5, 2018 Category: Neurology Authors: Junya Tsurukiri, Takahiro Ota, Hiroyuki Jimbo, Eitaro Okumura, Keigo Shigeta, Tatsuo Amano, Masayuki Ueda, Yuji Matsumaru, Yoshiaki Shiokawa, Teruyuki Hirano Source Type: research

Japanese Versus Non-Japanese Patients with Transient Ischemic Attack or Minor Stroke: Subanalysis of TIA registry.org
TIAregistry.org is an international cohort of patients with transient ischemic attack (TIA) or minor stroke within 7 days before enrollment in the registry. Main analyses of 1-year follow-up data have been reported.5 We conducted subanalysis on the baseline and 1-year follow-up data of Japanese patients.
Source: Journal of Stroke and Cerebrovascular Diseases - June 6, 2019 Category: Neurology Authors: Shinichiro Uchiyama, Takao Hoshino, Leila Sissani, Monteiro Tavares Linsay, Kenji Kamiyama, Taizen Nakase, Kazuo Kitagawa, Kazuo Minematsu, Kenichi Todo, Yasushi Okada, Jyoji Nakagawara, Ken Nagata, Hiroshi Yamagami, Takenori Yamaguchi, Pierre Amarenco, T Source Type: research

Ten-Year Cerebrovascular Disease Trend Occurrence by Population-based Stroke Registry in an Aging Japan Local Prefecture
Background: Cerebrovascular diseases are a major cause of death for Japanese people, but up-to-date national or prefectural incidences are unknown. We calculated the last 10-year cerebrovascular diseases incidence in an aging local prefecture in Japan with 1.2 million inhabitants and used the data to predict the future incidence. Methods: We retrospectively analyzed inventory surveys from the Iwate Stroke Registry (data from the whole Iwate Prefecture) from 2008 to 2017. We compared age-adjusted and age-specific incidence rates between the first half period from 2008 to 2012 and the last half period from 2013 to 2017.
Source: Journal of Stroke and Cerebrovascular Diseases - December 22, 2019 Category: Neurology Authors: Shinichi Omama, Kuniaki Ogasawara, Yoshihiro Inoue, Yasuhiro Ishibashi, Masaki Ohsawa, Toshiyuki Onoda, Kazuyoshi Itai, Kozo Tanno, Kiyomi Sakata Source Type: research

Outcome and effect of endovascular treatment in stroke associated with acute extracranial internal carotid artery occlusion: Single-center experience in Japan
Positive data from several randomized controlled trials (RCTs) of endovascular treatment (EVT) for acute ischemic stroke (AIS) patients with anterior circulation large vessel occlusion (ACLVO) have emerged. However, little evidence exists on EVT for acute extracranial internal carotid artery (EC-ICA) occlusion. We therefore analysed the outcome and effect of EVT on AIS due to ACLVO caused by EC-ICA occlusion, including tandem occlusion compared with that caused by pure intracranial artery occlusion.
Source: Journal of Stroke and Cerebrovascular Diseases - May 3, 2020 Category: Neurology Authors: Takashi Mizowaki, Atsushi Fujita, Satoshi Inoue, Ryuichi Kuroda, Seishirou Urui, Eiji Kurihara, Kohkichi Hosoda, Eiji Kohmura Source Type: research

Secondary stroke prevention with apixaban in nonvalvular atrial fibrillation: A subgroup analysis of the STANDARD study
Data on independent risk factors for stroke recurrence in Japanese patients with nonvalvular atrial fibrillation are limited.
Source: Journal of Stroke and Cerebrovascular Diseases - August 15, 2020 Category: Neurology Authors: Masahiro Yasaka, Michiaki Umeyama, Hirohide Kataoka, Hiroshi Inoue Source Type: research

Expanded Indication for Recombinant Tissue Plasminogen Activator from 3 to 4.5 h after Onset of Stroke in Japan
We examined the impact of expansion of the time window (from 3 to 4.5 hours) in the labeled indication for recombinant tissue-plasminogen activator (rt-PA) in August 2012 on the use of rt-PA for patients with acute ischemic stroke (AIS) and the outcomes of patients treated with rt-PA.
Source: Journal of Stroke and Cerebrovascular Diseases - October 8, 2020 Category: Neurology Authors: Yoshihisa Miyamoto, Shotaro Aso, Masao Iwagami, Kojiro Morita, Kiyohide Fushimi, Yoshifumi Hamasaki, Masaomi Nangaku, Kent Doi, Hideo Yasunaga Source Type: research

Endovascular Therapy for Acute Ischemic Stroke in Patients with Large-Vessel Occlusion due to Atherosclerotic Stenosis
This study aimed to evaluate the differences in clinical results between the two subtypes using data from a multicenter prospective registry (RESCUE-Japan Registry 2).
Source: Journal of Stroke and Cerebrovascular Diseases - July 24, 2021 Category: Neurology Authors: Manabu Shirakawa, Hidetoshi Matsukawa, Nobuyuki Sakai, Hiroshi Yamagami, Kanta Tanaka, Hirotoshi Imamura, Yasushi Matsumoto, Masataka Takeuchi, Hiroto Kageyama, Kazutaka Uchida, Takeshi Morimoto, Shinichi Yoshimura Source Type: research

Care-needs Certification in the National Long-Term Care Insurance is Useful for Assessment of Premorbid Function in Older Japanese Patients with Stroke
To investigate the effects of premorbid long-term care insurance (LTCI) care-need certification on functional improvement during acute hospitalization in older patients with stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - May 16, 2022 Category: Neurology Authors: Arisa Kamo, Masafumi Nozoe, Hiroki Kubo, Shinichi Shimada Source Type: research

Pediatric arterial ischemic stroke in Japan: Moyamoya disease or not
In this study, among 93 responders from physicians in 50 pediatric hospitals, consensus agreement, being available to treat pediatric AIS, was 90.3% in the use of intravenous tissue plasminogen activator (tPA) and 77.4% in mechanical thrombectomy.
Source: Journal of Stroke and Cerebrovascular Diseases - March 27, 2023 Category: Neurology Authors: Shunji Mugikura, Naoko Mori Tags: Letter to the Editor Source Type: research

Prognostic evaluation of branch atheromatous disease in the pons using carotid artery ultrasonography
In the 2017 fiscal year, stroke was the 3rd leading cause of death in Japan, after malignant neoplasms and heart diseases, according to a survey by the Ministry of Health, Labour, and Welfare of Japan.1 The most common type of stroke is ischemic stroke, and a large-scale epidemiologic survey on ischemic stroke in Japan, conducted from 1999 to 2000, found that, within this category, lacunar infarcts were the most common (36%), followed by atherothrombotic infarcts (31%), cardioembolic infarcts (20%), and undifferentiated types of ischemic stroke (6%).
Source: Journal of Stroke and Cerebrovascular Diseases - May 10, 2020 Category: Neurology Authors: Seiya Takahashi, Yumika Kokudai, Shinji Kurokawa, Hideyo Kasai, Ryuta Kinno, Yuriko Inoue, Hiromitsu Ezure, Hiroshi Moriyama, Kenjiro Ono, Naruhito Otsuka, Yasuhiko Baba Source Type: research

Temporal Trends in Clinical Characteristics and Door-to-Needle Time in Patients Receiving Intravenous Tissue Plasminogen Activator: A Retrospective Study of 4 Hospitals in Japan
Background: Intravenous recombinant tissue plasminogen activator (rt-PA) has become a common treatment for acute ischemic stroke and has highly time-dependent benefits. We aimed to clarify temporal trends regarding the frequency and characteristics of patients receiving rt-PA and explore factors associated with door-to-needle time (DNT) in Japanese emergency hospitals. Methods: Consecutive patients who received intravenous rt-PA for acute ischemic stroke from October 2005 to December 2015 were retrospectively registered from 4 hospitals.
Source: Journal of Stroke and Cerebrovascular Diseases - August 9, 2019 Category: Neurology Authors: Koji Tanaka, Shoji Matsumoto, Takeshi Yamada, Sukehisa Nagano, Kei-ichiro Takase, Taketo Hatano, Ryo Yamasaki, Jun-ichi Kira Source Type: research

Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Associated With a Novel In-Frame Mutation in the NOTCH3 Gene in a Japanese Patient
Here, we report a case involving a 67-year-old Japanese woman with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) associated with a novel in-frame complex rearrangement in the NOTCH3 gene. The patient had gradually developed cognitive impairment since the occurrence of an ischemic stroke at the age of 53 years. Her mother had a history of stroke and dementia. Fluid-attenuated inversion recovery magnetic resonance imaging of the brain showed hyperintense lesions in the bilateral temporal poles, external capsules, and periventricular white matter accompanied by multiple c...
Source: Journal of Stroke and Cerebrovascular Diseases - November 3, 2019 Category: Neurology Authors: Yuho Takeshi, Satoshi Suda, Takashi Shimoyama, Junya Aoki, Kentaro Suzuki, Seiji Okubo, Ikuko Mizuta, Toshiki Mizuno, Kazumi Kimura Tags: Case Report Source Type: research

Reproducible Presyncope Due to Osteophyte Compression Into Transverse Foramen of the C5 Vertebra
Beauty parlor stroke syndrome is characterized by the development of various neurological symptoms during cervical hyperextension, followed by inadequate blood flow through the posterior circulation of the brain. However, there are few reports of beauty parlor stroke syndrome wherein the cause of the posterior circulatory inadequacy has been directly identified. Here we report a case where we could directly detect the origin of the posterior circulatory inadequacy. A 76-year-old Japanese man with hypertension presented with presyncope following cervical retroflexion.
Source: Journal of Stroke and Cerebrovascular Diseases - January 19, 2021 Category: Neurology Authors: Yuya Kano, Kentaro Yamada, Masahiro Muto, Masahiro Oomura, Noriyuki Matsukawa Tags: Case Report Source Type: research

Modified Rankin scale assessment by telephone using a simple questionnaire
: The modified Rankin Scale (mRS) is widely used as a measure of post-stroke physical disability in clinical stroke trials; however, it is affected by inter-rater discrepancies. A Japanese version of the simplified mRS questionnaire (J-RASQ) has the potential to overcome the inter-rater discrepancies and might be feasible for clinical surveys. We aimed to determine the reliability of J-RASQ in a telephone survey administered by non-medical staff.
Source: Journal of Stroke and Cerebrovascular Diseases - August 30, 2022 Category: Neurology Authors: Kenichiro Yi, Makoto Nakajima, Tomoaki Ikeda, Mineko Yoshigai, Mitsuharu Ueda Source Type: research

The Risk of Intracranial Hemorrhage in Japanese Patients with Acute Large Vessel Occlusion; subanalysis of the RESCUE-Japan registry
Recanalization therapies such as intravenous thrombolysis (IVT) or endovascular treatment (EVT) improve acute ischemic stroke outcomes; however, they carry the risk of intracranial hemorrhage (ICH). The present study assessed the frequency and predictive factor of ICH in Japanese patients with acute large vessel occlusion.
Source: Journal of Stroke and Cerebrovascular Diseases - February 25, 2016 Category: Neurology Authors: Yukiko Enomoto, Shinichi Yoshimura, Yusuke Egashira, Hiroshi Yamagami, Nobuyuki Sakai, Committee of Endovascular Salvage for Cerebral Ultra-acute Embolism (RESCUE)-Japan Study Group Source Type: research

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