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Association of Initial Potassium Levels with the Type of Stroke in the Emergency Department
Early differentiation of hemorrhagic stroke from ischemic stroke in patients with suspected stroke is essential for subsequent management of the patient. While serum potassium level has been suggested as a marker of acute hemorrhagic conditions,1, 2 little is known about whether the initial serum potassium levels differ based on the type of stroke. If serum potassium levels can help differentiate hemorrhagic stroke from ischemic stroke, this information can be applied in deciding subsequent treatment procedures (e.g., catheter intervention, tissue plasminogen activator administration, and antihypertensive therapy) in setti...
Source: Journal of Stroke and Cerebrovascular Diseases - May 30, 2021 Category: Neurology Authors: Kiyomitsu Fukaguchi, Hiroshi Yamagami, Shoko Soeno, Konan Hara, Toru Shirakawa, Tomohiro Sonoo, Kensuke Nakamura, Tadahiro Goto Source Type: research

Long Non-Coding KCNQ1OT1 Promotes Oxygen-Glucose-Deprivation/Reoxygenation-Induced Neurons Injury Through Regulating MIR-153-3p/FOXO3 Axis
In this study, we aimed to investigate the role of LncRNA-Potassium Voltage-Gated Channel Subfamily Q Member 1 opposite strand/antisense transcript 1 (KCNQ1OT1) in cerebral I/R induced neuronal injury, and its underlying mechanisms. Methods: Primary mouse cerebral cortical neurons treated with oxygen-glucose deprivation and reoxygenation (OGD/R) in vitro and mice subjected to middle cerebral artery occlusion (MCAO) and reperfusion were used to mimic cerebral I/R injury.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Hua-Jun Wang, Xia-Lin Tang, Gan Huang, Ying-Bin Li, Rui-Huan Pan, Jie Zhan, Ye-Kun Wu, Jian-Feng Liang, Xiao-xin Bai, Jun Cai Source Type: research

Serum Glucose and Potassium Ratio as Risk Factors for Cerebral Vasospasm after Aneurysmal Subarachnoid Hemorrhage
Objective: Cerebral vasospasm is associated with poor prognosis in patients with aneurysmal subarachnoid hemorrhage (SAH), and biomarkers for predicting poor prognosis have not yet been established. We attempted to clarify the relationship between serum glucose/potassium ratio and cerebral vasospasm in patients with aneurysmal SAH. Methods: We studied 333 of 535 aneurysmal SAH patients treated between 2006 and 2016 (123 males, 210 females; mean age 59.7 years; range 24-93). We retrospectively analyzed the relationship between cerebral vasospasm grade and clinical risk factors, including serum glucose/potassium ratio.
Source: Journal of Stroke and Cerebrovascular Diseases - May 2, 2019 Category: Neurology Authors: Fumihiro Matano, Yu Fujiki, Takayuki Mizunari, Kenta Koketsu, Tomonori Tamaki, Yasuo Murai, Hiroyuki Yokota, Akio Morita Source Type: research

Factors Influencing Quality of Life in Stroke Patients: Focus on Eating Habits
This study aimed to identify lifestyle factors about eating habits that may affect the quality of life (QOL) in elderly stroke patients. Methods: Fifty elderly patients with a first-ever stroke were enrolled. QOL was assessed by the Stroke and Aphasia QOL Scale-39-J. Lifestyle factors about eating habits were collected using questionnaires (Questions 1-17) for the intake of salt, calcium, magnesium, potassium, taurine, fiber, and protein, and the frequency of breakfast.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2019 Category: Neurology Authors: Reina Chiba, Saya Tominaga, Kasumi Mikami, Maiko Kitajima, Mayumi Urushizaka, Toshiko Tomisawa, Junko Chiba, Joji Hagii, Minoru Yasujima, Tomohiro Osanai Source Type: research