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Geriatric nutrition risk index predicts prolonged post-stroke dysphagia in acute ischemic stroke
Post-stroke dysphagia (PSD) is a common complication after stroke. Malnutrition inhibits stroke recovery and is associated with stroke mortality. However, no studies have investigated the effects of nutritional state at admission on prolonged PSD.
Source: Journal of Stroke and Cerebrovascular Diseases - June 7, 2023 Category: Neurology Authors: Hajime Ikenouchi, Kei Nozue, Satoru Yamaguchi, Tatsuo Miyamoto, Naoki Yamamoto, Kaoru Endo Source Type: research

Response to the Letter to the editor, JSCVD-D-22-01922
Tokyo Bay Rehabilitation Hospital started a multi-disciplinary nutrition support team (NST) when it was established in 2007. The rehabilitation programs managed by physiatrists aim to achieve the highest activities of daily living (ADLs) for patients with subacute stroke, regardless of the length of stay (LOS).
Source: Journal of Stroke and Cerebrovascular Diseases - January 20, 2023 Category: Neurology Authors: Takayuki Kamimoto, Keiichiro Shindo, Tadasuke Shimomura, Tomonori Akimoto, Takeshi Yamada, Naoki Mori, Keiko Nakao, Masahiro Tsujikawa, Kaoru Honaga, Takeshi Kutsuna, Kazuhisa Hiramatsu, Kunitsugu Kondo, Meigen Liu Tags: Letter to the Editor Source Type: research

Ro25-6981 alleviates neuronal damage and improves cognitive deficits by attenuating oxidative stress via the Nrf2/ARE pathway in ischemia/reperfusion rats
Cerebral ischemia ‒reperfusion injury (CIRI) refers to the phenomenon that structural damage and dysfunction of the brain are further aggravated when blood perfusion is restored after cerebral ischemia for a certain time, which mainly causes apoptosis or necrosis of nerve cells.1 CIRI will result in severe cognitiv e and motor dysfunction.2,3 The current treatments are mainly thrombolysis, intervention, nutritional nerve, and rehabilitation training, but they cannot completely restore the neurological function of patients.
Source: Journal of Stroke and Cerebrovascular Diseases - December 29, 2022 Category: Neurology Authors: Xiuxian Gao, Fei Chen, Xinqi Xu, Jinfeng Liu, Fuxing Dong, Yaping Liu Source Type: research

Comment on relationship between initial nutritional status and functional independence measures at discharge in subacute stroke
In a study recently published in this journal, Kamimoto et al.1 reported the relationship between initial nutritional status and functional independence measures at discharge (FIMTM) in subacute stroke. Rehabilitation nutrition in stroke is very important, because Yoshimura et al. reported that the presence or absence of sarcopenia2 and hemoglobin level3 at admission, which are associated with nutrition status, were related to the recovery of ADL after stroke. However, the report by Kamimoto et al.
Source: Journal of Stroke and Cerebrovascular Diseases - December 23, 2022 Category: Neurology Authors: Shingo Kakehi, Ryohei Takemura, Hidetaka Wakabayashi Tags: Letter to the Editor Source Type: research

The association between nutritional intake one week after admission and outcome in acute ischemic stroke patients
In the acute stage of stroke, there are multiple factors that disturb oral intake, such as impaired consciousness and dysphagia.1,2 Malnutrition is an important problem in acute stroke patients ’ care. Some studies have shown that adequate nutritional management can improve the length of hospitalization, long-term outcome, and mortality.3–6 Poor oral status is associated with sarcopenia, which reduces muscle mass and strength in postacute stroke patients.7 Sarcopenia brought on by maln utrition diminishes activities of daily living (ADLs) and has an adverse impact on the improvement of swallowing function.
Source: Journal of Stroke and Cerebrovascular Diseases - September 29, 2022 Category: Neurology Authors: Futoshi Eto, Tomohisa Nezu, Shiro Aoki, Teppei Kamimura, Hiroyuki Naito, Yuji Shiga, Naohisa Hosomi, Hirofumi Maruyama Source Type: research

Relationship between initial nutritional status and functional independence measures at discharge in subacute stroke
This retrospective study examined the association between nutritional status at admission and functional independence measure (FIM ™) at discharge.
Source: Journal of Stroke and Cerebrovascular Diseases - September 14, 2022 Category: Neurology Authors: Takayuki Kamimoto, Keiichiro Shindo, Tadasuke Shimomura, Tomonori Akimoto, Takeshi Yamada, Naoki Mori, Keiko Nakao, Masahiro Tsujikawa, Kaoru Honaga, Takeshi Kutsuna, Kazuhisa Hiramatsu, Kunitsugu Kondo, Meigen Liu Source Type: research

Use of Antipsychotics is Negatively Associated with Muscle Strength in Older Adults with Sarcopenia after Stroke
The mainstay of treatment for sarcopenia is muscle mass and strength increase through exercise and nutritional intervention.1 A systematic review and meta-analysis of the effects of combined exercise and nutritional therapy for sarcopenia in older people showed that this combination may have positive effects on improving walking speed within 3 months of intervention.2 Furthermore, supplementation with whey protein, essential amino acids, and vitamin D, in conjunction with age-appropriate exercise has been reported to boost fat-free mass and strength.
Source: Journal of Stroke and Cerebrovascular Diseases - July 3, 2022 Category: Neurology Authors: Eiji Kose, Yoshihiro Yoshimura, Hidetaka Wakabayashi, Ayaka Matsumoto Source Type: research

Association of Physical Activity and Nutritional Intake with Muscle Quantity and Quality Changes in Acute Stroke Patients
Stroke leads to muscle wasting due to physical inactivity and malnutrition.1,2 The loss of muscle mass carried over from the acute phase to the recovery phase during rehabilitation reduces the home discharge rate and activity of daily living.3 Therefore, to provide more suitable rehabilitation after stroke, it is necessary to initiate tactics to prevent muscle loss from the acute stroke phase. However, only few studies have examined the longitudinal changes in muscle properties and related factors in the acute phase.
Source: Journal of Stroke and Cerebrovascular Diseases - March 16, 2022 Category: Neurology Authors: Hiroki Tanaka, Gakuto Kitamura, Manabu Nankaku, Masashi Taniguchi, Kenichiro Shide, Miharu Fujita, Megumi Ida, Shinobu Oshima, Takayuki Kikuchi, Takakuni Maki, Ryosuke Ikeguchi, Susumu Miyamoto, Ryosuke Takahashi, Nobuya Inagaki, Shuichi Matsuda, Noriaki Source Type: research

Phase Angle as an Indicator of Baseline Nutritional Status and Sarcopenia in Acute Stroke
The outcomes of stroke patients are related to sex, neurological severity, activities of daily living (ADL) before stroke onset, nutritional status, and presence of sarcopenia.1 –5 Stroke patients with malnutrition or sarcopenia could improve their outcomes by improving malnutrition and sarcopenia with exercise therapy and nutritional support.6,7 Therefore, the nutritional status and the presence of sarcopenia in stroke patients need to be evaluated early after stroke ons et in order to improve outcomes with timely and appropriate interventions.
Source: Journal of Stroke and Cerebrovascular Diseases - November 23, 2021 Category: Neurology Authors: Yoichi Sato, Yoshihiro Yoshimura, Takafumi Abe Source Type: research

Measuring and Monitoring Skeletal Muscle Mass after Stroke: A Review of Current Methods and Clinical Applications
Muscle mass at admission is important to survive stroke, and stroke-induced sarcopenia is a serious problem because of its poor prognosis. Muscle mass measurement and monitoring are essential for appropriate rehabilitation and nutrition management. However, few reviews are available about the muscle mass measurement and monitoring after stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - March 20, 2021 Category: Neurology Authors: Nobuto Nakanishi, Kazuki Okura, Masatsugu Okamura, Keishi Nawata, Ayato Shinohara, Kohei Tanaka, Sho Katayama Source Type: research

Reducing the Risk of Stroke in Patients with Impaired Renal Function: Nutritional Issues
Patients with renal failure have extremely high cardiovascular risk; in dialysis patients the risk of stroke is increased approximately 10-fold over that in the general population. Reasons include not only a high prevalence of traditional risk factors such as diabetes, hypertension and dyslipidemia, but also the accumulation of toxic substances that are eliminated by the kidneys, so have very high levels in patients with renal failure. These include plasma total homocysteine, asymmetric dimethylarginine, thiocyanate, and toxic products of the intestinal microbiome (Gut-Derived Uremic Toxins; GDUT), which include trimethyla...
Source: Journal of Stroke and Cerebrovascular Diseases - November 17, 2020 Category: Neurology Authors: J. David Spence Tags: Review Article Source Type: research

Hematological Abnormalities and Malnutrition Mediate Pathway between Cancer and Outcomes in Ischemic Stroke Patients
The present study aimed to examine whether variables including D-dimer, high-sensitivity C-reactive protein (hsCRP), hemoglobin, platelet count, and nutritional status mediate the pathway between cancer and ischemic stroke outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - July 15, 2020 Category: Neurology Authors: Yasufumi Gon, Daijiro Kabata, Tomohiro Kawano, Hideaki Kanki, Kenichi Todo, Tsutomu Sasaki, Ayumi Shintani, Hideki Mochizuki Source Type: research

Prognostic significance of pre-procedural prognostic nutritional index in patients with carotid artery stenting
Inflammation and malnutrition play a critical role in the outcomes of patients undergoing carotid artery stenting (CAS). Prognostic nutritional index (PNI) is commonly utilized to evaluate the peri-operative immune-nutritional status of patients undergoing colorectal cancer surgery and is independently associated with survival. We assessed the association between immune-nutritional status, indexed by PNI, and outcomes in CAS patients.
Source: Journal of Stroke and Cerebrovascular Diseases - July 15, 2020 Category: Neurology Authors: L ütfi Öcal, Ayhan Küp, Muhammed Keskin, Sinan Cerşit, Mehmet Çelik, Hayati Eren, Mustafa Ozan Gürsoy, Burak Öztürkeri, Bayram Öztürk, Mehmet Muhsin Turkmen Source Type: research

A Comparative Study of Two Tube Feeding Methods in Patients with Dysphagia After Stroke: A Randomized Controlled Trial
Background: Dysphagia is a common symptom seen in stroke patients, it not only affects patients' nutrition supply, but also causes aspiration pneumonia. To solve the problem of nutritional support for patients with dysphagia after stroke, nasogastric tubes are routinely indwelling to provide nutrition in China. However, this feeding method sometimes causes food reflux, aspiration, pneumonia, and often affects the patients ’ comfort and self-image acceptance. Aim: The aim of this study was to determine whether a new feeding method called intermittent oroesophageal (IOE) tube feeding compared with continuous nasogastric tu...
Source: Journal of Stroke and Cerebrovascular Diseases - January 12, 2020 Category: Neurology Authors: Wei Juan, Huang Zhen, Feng Yan-Ying, Yang Hui-Xian, Zhong Tao, Guo Pei-Fen, Huo Jian-Tian Source Type: research

Race, Socioeconomic Status, and Gastrostomy after Spontaneous Intracerebral Hemorrhage
Introduction: Spontaneous intracerebral hemorrhage is a disabling form of stroke, and some patients will require nutritional interventions for dysphagia. We sought to determine if socioeconomic status indicators mediate whether minorities undergo gastrostomy tube placement. Materials and Methods: Patients with spontaneous intracerebral hemorrhage were enrolled in a single center, observational cohort study from 2010 to 2017. A socioeconomic index score was imputed using neighborhood characteristics by patients ’ ZIP code, according to an established method utilizing 6 indicators of wealth/income, education, and occupation.
Source: Journal of Stroke and Cerebrovascular Diseases - December 11, 2019 Category: Neurology Authors: Roxanna M. Garcia, Shyam Prabhakaran, Christopher T. Richards, Andrew M. Naidech, Matthew B. Maas Source Type: research

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