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Peri-device leakage not CHA2DS2-VASc is associated with post-left atrial appendage closure cardiovascular event
In patients with non-valvular atrial fibrillation (NVAF), the left atrial appendage occluder (LAAO) is an alternative treatment for stroke prevention. However, thromboembolic event still occur, and the predictors are unknown.
Source: Journal of Stroke and Cerebrovascular Diseases - September 10, 2022 Category: Neurology Authors: Pang-Shuo Huang, Fu-Chun Chiu, Hsiao-Liang Cheng, Jung-Cheng Hsu, Su-Kiat Chua, Chun-Yuan Chu, Ting-Tse Lin, Jien-Jiun Chen, Chia-Ti Tsai Source Type: research

Effects of Sodium/Glucose Cotransporter Inhibitors on Atrial Fibrillation and Stroke: A Meta-Analysis
Globally, the number of people estimated to have diabetes mellitus (DM) in 2019 was 463 million, and the estimated number is expected to rise to 578 million people by 2030.1 DM is also associated with an increased risk of atrial fibrillation (AF), 2 and has shown to be an independent risk factor for stroke in patients with AF.3 A meta-analysis of 102 studies further showed that patients with diabetes have a higher risk of all subtypes of stroke (ischemic, hemorrhagic and unclassified stroke).4 This has generated great interest in anti-hyperglycemic agents and their ability to reduce the cardiovascular complications of diabetes.
Source: Journal of Stroke and Cerebrovascular Diseases - October 22, 2021 Category: Neurology Authors: How Ting Ong, Yao Hao Teo, Yao Neng Teo, Nicholas LX Syn, Caitlin Fern Wee, Shariel Leong, Alicia Swee Yan Yip, Ray Meng See, Adriel Zhi Hen Ting, Alys ZQ Chia, Alex Jia Yang Cheong, Benjamin Yong-Qiang Tan, Jamie Sin-Ying Ho, Leonard Leong-Litt Yeo, Aloy Source Type: research

Migraine with Visual aura and the Risk of Stroke- a Narrative Review
Patients with migraine with visual aura (MwvA) often present to eye care providers for evaluation. A thorough ophthalmological history and examination is needed to exclude ophthalmologic disorders. Additionally, it has been increasingly recognized that MwvA is associated with ischemic stroke (IS). The aim of this narrative review is to provide a comprehensive overview of the differential diagnosis of MwvA and its association with IS.
Source: Journal of Stroke and Cerebrovascular Diseases - August 27, 2021 Category: Neurology Authors: Meng-Chun Chiang, Oana M. Dumitrascu, Nikita Chhabra, Chia-Chun Chiang Tags: Review Article Source Type: research

Cerebral venous thrombosis following COVID-19 vaccination
We appreciate the literature review by Abdalkader et al.1 to summarize the clinical epidemiology and features of cerebral venous thrombosis (CVT) in patients with coronavirus disease 2019 (COVID-19). Based on the meta-analysis performed by Baldini et al.,2 the estimated proportion of CVT cases among hospitalized patients with COVID-19 was 0.08%; therefore, it is not surprising that COVID-19 associated CVT had not been given much attention compared to the more common deep vein thrombosis and pulmonary embolism events in this patient population.
Source: Journal of Stroke and Cerebrovascular Diseases - May 10, 2021 Category: Neurology Authors: Chia Siang Kow, Syed Shahzad Hasan Tags: Letter to the Editor Source Type: research

Anticoagulant approach in COVID-19 patients with cerebral venous thrombosis
We appreciate Klein et al. [1] for reporting the case of cerebral venous thrombosis accompanied by hemorrhagic infarct in a young patient with novel coronavirus disease 2019 (COVID-19). The reporting of such a case would raise the awareness of the possibility of the occurrence of cerebral venous thrombosis in the course of COVID-19, especially among the young adults present with COVID-19 and neurological symptoms.
Source: Journal of Stroke and Cerebrovascular Diseases - August 2, 2020 Category: Neurology Authors: Chia Siang Kow, Abdullah Faiz Zaihan, Syed Shahzad Hasan Source Type: research

RAcial Disparities in Ich after IV-tPA and Neurointerventional Treatment (RADIANT)
Objective: To study the rate of symptomatic intracerebral hemorrhage (SxICH) and major systemic hemorrhage (MSH) after acute stroke treatments among different ethnicities/races. Background: Studies have reported ethnic/racial disparities in intravenous tPA treatment (IV tPA). The adverse outcome of tPA and/or intra-arterial intervention (IA) among different ethnicities/races requires investigation. Methods: We retrospectively reviewed all patients from an IRB-approved registry between June 2004 and June 2018.
Source: Journal of Stroke and Cerebrovascular Diseases - November 25, 2019 Category: Neurology Authors: Chia-Chun Chiang, Dawn M. Meyer, Brett C. Meyer, Kunal Agrawal, Royya Modir Source Type: research

Association Between Total Cholesterol and 5 year Mortality in Patients with Carotid Artery Stenosis and Poststroke Functional Dependence
Background: Aggressive lipid-lowering treatment reduces the risk of cardiovascular events, but remains controversial in stroke patients. We investigate the influence of total cholesterol level on 5-year outcomes of ischemic stroke patients with high-grade internal carotid artery (ICA) stenosis and poststroke functional dependence.Methods: One-hundred and ninety-six acute ischemic stroke patients with high-grade ICA stenosis and modified Rankin Scale score ≥ 3 upon discharge were enrolled and prospectively observed for 5 years.
Source: Journal of Stroke and Cerebrovascular Diseases - January 11, 2019 Category: Neurology Authors: Yen-Ju Lung, Wei-Chieh Weng, Chia-Lun Wu, Wen-Yi Huang Source Type: research

Acute Stroke Patients with Newly Diagnosed Diabetes Mellitus Have Poorer Outcomes than Those with Previously Diagnosed Diabetes Mellitus
This study aims to determine the prevalence of NDDM in the ASPs and to compare the outcome in NDDM and previously diagnosed DM (PDDM) in Cameroon.
Source: Journal of Stroke and Cerebrovascular Diseases - May 18, 2018 Category: Neurology Authors: Yacouba Njankouo Mapoure, Hamadou Ba, Chia Mark Ayeah, Caroline Kenmegne, Henry Namme Luma, Alfred Kongnyu Njamnshi Source Type: research

The Prognostic Value of Serum Uric Acid in the Acute Phase of Ischemic Stroke in Black Africans
This study aims to determine the prevalence of hyperuricemia and its association with the outcome of patients with acute ischemic stroke in a tertiary care hospital.
Source: Journal of Stroke and Cerebrovascular Diseases - November 15, 2017 Category: Neurology Authors: Yacouba Njankouo Mapoure, Chia Mark Ayeah, Hamadou Ba, Romuald Hentchoya, Henry Namme Luma Source Type: research

Association between Atrial Fibrillation and Three-Year Mortality in Nondiabetic Patients with Acute First-Ever Ischemic Stroke
Diabetes mellitus (DM) is a risk factor for atrial fibrillation (AF) and is known to be an important risk factor for death from stroke. The influence of AF on long-term outcomes in patients with ischemic stroke remains controversial. To clarify the exact influence of AF on stroke outcome and exclude the effect from DM, we investigated the influence of AF on the 3-year outcomes of nondiabetic patients with acute first-ever ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - July 28, 2016 Category: Neurology Authors: Chun-Hsueh Chu, Wei-Chieh Weng, Feng-Chieh Su, Tsung-I Peng, Yu-Yi Chien, Chia-Lun Wu, Kuang-Yung Lee, Yi-Chia Wei, Shun-Wen Lin, Yi-Jing Yu, Wen-Yi Huang Source Type: research