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Prevalence and predictors of low folate levels among stroke survivors in a country without mandatory folate food fortification: Analysis of a Ghanaian sample
Vitamin supplementation with folic acid (FA) reduces hyperhomocysteinemia (Hcy), a vascular risk factor with a strong, graded, and independent association with stroke and other vascular diseases.1 Available data suggest that a 25% reduction in total plasma homocysteine level is accompanied by a 19% lower stroke risk.1,2 Evidence from clinical trials on the effect of folate supplementation on mitigation of stroke risk has however been conflicting. A synthesis of clinical trial data has shown that supplemental FA had a neutral effect on reducing vascular events in countries with a mandate for folate fortification of food, fo...
Source: Journal of Stroke and Cerebrovascular Diseases - July 20, 2023 Category: Neurology Authors: Fred Stephen Sarfo, Richard Boateng, Priscilla Abrafi Opare-Addo, Rexford Adu Gyamfi, Samuel Blay Nguah, Bruce Ovbiagele Source Type: research

Prevalence and risk factors of stroke recurrence in ghana and nigeria
Recurrent stroke prevention is vital for promoting optimal quality of life in stroke survivors. However, data on the burden and risk factors of recurrent stroke in sub-Saharan Africa is limited. We assessed the burden, risk factors and fatality from recurrent stroke in Ghana and Nigeria.
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2023 Category: Neurology Authors: Osahon Jeffery Asowata, Fred Stephen Sarfo, Onoja Matthew Akpa, Joshua Akinyemi, Akinkunmi Paul Okekunle, Adekunle G. Fakunle, Godwin Ogbole, Albert Akpalu, Kolawole Wahab, Reginald Obiako, Morenikeji Komolafe, Godwin Osaigbovo, Lukman Owolabi, Rufus Akin Source Type: research

Determinants of stroke mortality among west africans: findings from the siren study
Stroke is one of the leading causes of death and disability in low-and-medium-income countries, but the pattern and determinants of stroke fatality are yet to be clearly understood among Africans. We assessed the determinants of stroke mortality among adults from 15 sites in Ghana and Nigeria in the Stroke Investigative Research and Educational Network (SIREN) study in West Africa.
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2023 Category: Neurology Authors: Akinkunmi Paul Okekunle, Fred Stephen Sarfo, Onoja Matthew Akpa, Osahon Jeffery Asowata, Joshua Akinyemi, Adekunle Fakunle, Godwin Ogbole, Albert Akpalu, Kolawole Wahab, Reginald Obiako, Morenikeji Komolafe, Godwin Osaigbovo, Lukman Owolabi, Rufus Akinyem Source Type: research

The level of stroke severity amongst early and late presenters and their functional outcomes during a 30-day period in a teaching hospital in ghana
This study aimed at examining the clinical presentation of patients with acute ischaemic stroke, who presented early ( 4.5 hrs) against their functional outcomes during a 30-day period.
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2023 Category: Neurology Authors: F. Duodu, D. Brodie Mends, P. Pekyi-Boateng, B. Agbinko-Djobalar, J. Abugre, P. Adjei, A Akpalu, K Nkromah Source Type: research

Time to ct scan imaging after symptom onset among ischeamic stroke patients presenting to a quaternary hospital in ghana
This study sought to determine the time of onset of symptoms to the time a CT imaging was done among patients presenting with acute stroke at the Korle-Bu Teaching Hospital.
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2023 Category: Neurology Authors: F. Duodu, D. Brodie Mends, B. Agbinko-Djobalar, P. Pekyi-Boateng, M. Amerwornu, P Adjei, A Akpalu, K Nkromah Source Type: research

Long-term determinants of death after stroke in Ghana: Analysis by stroke types & subtypes
Data on longer-term survival (>5 years) after stroke in sub-Saharan Africa (SSA) are limited in the literature. The prospects of survival after a stroke in SSA is of considerable interest given the steep rise in stroke burden,1,2 the relatively younger age of stroke onset and the under-resourced health care delivery on the continent. Poor short-term survival outcomes are well documented3,4 but there is a need for more longitudinal data to inform policy directives on resource allocation for stroke care.
Source: Journal of Stroke and Cerebrovascular Diseases - August 1, 2022 Category: Neurology Authors: Fred Stephen Sarfo, John Akassi, Emmanuel Ofori, Bruce Ovbiagele Source Type: research

Feasibility, acceptability, and appropriateness of the phone based interventions under nurse guidance after stroke (pings) in ghana
PINGS is a clinical trial to evaluate a nurse-led mHealth technology - centered approach to maintaining BP control among recent stroke survivors with hypertension in Ghana. PINGS involves domiciliary BP self-monitoring, mobile phone consultations, phone alerts as reminders, and patient education via text messages. We assessed the feasibility, acceptability, and appropriateness of PINGS from the perspective of health workers in general - not necessarily working in stroke rehabilitation.
Source: Journal of Stroke and Cerebrovascular Diseases - March 20, 2022 Category: Neurology Authors: Melvin K. Agbogbatey, Fred S. Sarfo, Alexis Beyuo, Kwaku Duah, Patrick Agasiya, Raelle Tagge, Bruce Ovbiagele, John H. Amuasi Source Type: research

Dominant patterns of illicit substance use and odds of stroke among west africans: findings from the siren study
This study assessed the relationship between ISU and the risk of stroke among indigenous Africans from Ghana and Nigeria.
Source: Journal of Stroke and Cerebrovascular Diseases - March 20, 2022 Category: Neurology Authors: Ezinne Uvere, Joshua Odunayo Akinyemi, Akinkunmi Paul Okekunle, Osahon Jeffery Asowata, Onoja Matthew Akpa, Fred Stephen Sarfo, Godwin Ogbole, Albert Akpalu, Kolawole Wahab, Reginald Obiako, Morenikeji Komolafe, Bimbo Fawale, Lukman Owolabi, Rufus Akinyem Source Type: research

National health insurance scheme: a means to effective stroke prevention among hypertensives in subsaharan africa
Uncontrolled hypertension is a leading cause of stroke in Sub-Saharan Africa. Factors affecting blood pressure control include low income, sedentary lifestyle and unhealthy diet. We sought to determine the role of National Health Insurance Scheme (NHIS) in achieving good blood control among hypertensives in Ghana and Nigeria and thus prevention of stroke and other cardiovascular complications of uncontrolled hypertension.
Source: Journal of Stroke and Cerebrovascular Diseases - March 20, 2022 Category: Neurology Authors: T.I.A. Oseni, B.F. Dele-Ojo, B. Paa-Kwesi, D. Fifi, C.P. Echieh, B.S. Alabi, B. Tayo Source Type: research

Prevalence and Predictors of Multivitamin Supplement Use After Stroke in Ghana
Multivitamin supplementation is widely practiced in high-income countries due to a popular belief of its health promotion and disease prevention benefits. Evidence for their purported efficacy has been mixed. Regarding the efficacy of multivitamins on prevention of cardiovascular disease, cancer, or all-cause mortality, some studies have shown no effect,1 –4 harmful effects,5,6 and beneficial effects.7,8 Three prospective studies have evaluated the effect of multivitamin use on stroke prevention with two showing negative outcomes3,5 and the third among 72,000 Japanese showing frequent use of multivitamins was associated ...
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2021 Category: Neurology Authors: Fred Stephen Sarfo, Bruce Ovbiagele Source Type: research

Factors Linked to Chronic Kidney Disease Among Stroke Survivors in Ghana
Stroke and chronic kidney disease (CKD) are major health problems across several regions of the globe. The Global Burden of Disease (GBD) collaborators have estimated the global lifetime risk of stroke for adults 25 years or older at 24.9% in 2016.1 An estimated 11-13% of the population worldwide has kidney disease.2 Both stroke and renal disease share traditional vascular risk factors such as hypertension, diabetes, obesity, dyslipidemia and obesity.3 Among ischemic stroke patients, 20% to 35% have CKD4,5 while 20 to 46% of patients with acute intracerebral hemorrhage have CKD.
Source: Journal of Stroke and Cerebrovascular Diseases - March 8, 2021 Category: Neurology Authors: Fred Stephen Sarfo, Martin Agyei, Isaac Ogyefo, Priscilla Abrafi Opare-Addo, Bruce Ovbiagele Source Type: research

Apparent Treatment Resistant Hypertension Among Stroke Survivors in Ghana
There are limited data evaluating the characteristics of apparent treatment-resistant hypertension (aTRH) among stroke survivors in sub-Saharan Africa. We aimed to conduct a comparative analysis of the frequency and factors associated with aTRH among stroke survivors and stroke-free individuals with hypertension in Ghana.
Source: Journal of Stroke and Cerebrovascular Diseases - October 21, 2020 Category: Neurology Authors: Fred Stephen Sarfo, Bruce Ovbiagele Source Type: research

Risk Factor Control in Stroke Survivors with Diagnosed and Undiagnosed Diabetes: A Ghanaian Registry Analysis
According to the World Health Organization (WHO), more than 80% of worldwide diabetes (DM)-related deaths presently occur in low- and middle- income countries (LMIC). DM-related deaths is projected to double over the next 20 years.1,2 As of 2012, ∼14 million Africans (4.8%) had diabetes mellitus (DM), and 81% were undiagnosed (vs. 50% worldwide), making Africa the continent with the highest proportion of people with undiagnosed DM.3 Projections for sub-Saharan Africa (SSA) indicate diabetes will rise by 71–23.9 million by 2030 (predicted global increase is 37%).
Source: Journal of Stroke and Cerebrovascular Diseases - September 22, 2020 Category: Neurology Authors: Fred Stephen Sarfo, John Akassi, Martin Agyei, Samuel Kontoh, Bruce Ovbiagele Source Type: research

Prevalence, Trajectory, and Predictors of Poststroke Fatigue among Ghanaians
Poststroke fatigue (PSF) is rife among stroke survivors and it exerts a detrimental toll on recovery from functional deficits. The burden of PSF is unknown in sub-Saharan Africa. We have assessed the prevalence, trajectory, and predictors of PSF among 60 recent Ghanaian stroke patients.
Source: Journal of Stroke and Cerebrovascular Diseases - February 20, 2019 Category: Neurology Authors: Fred S. Sarfo, Patrick Berchie, Arti Singh, Michelle Nichols, Maria Agyei-Frimpong, Carolyn Jenkins, Bruce Ovbiagele, On behalf of PINGS Study Investigators Source Type: research

Recurrent Stroke in a Ghanaian Patient With Polycythemia
Polycythemia is a rare but important preventable cause of stroke with potential for recurrence when not identified and appropriately managed.
Source: Journal of Stroke and Cerebrovascular Diseases - December 27, 2018 Category: Neurology Authors: Patrick O. Berchie, Fred Stephen Sarfo, Ohene K. Opare-Sem, Bruce Ovbiagele Source Type: research

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