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Visual stroke symptom triage tool to reduce delays due to limited English proficiency in Emergency department stroke activations
Limited English proficiency (LEP) may contribute to delays in care and worse outcomes in patients hospitalized with stroke. Limited access to interpreter services leads to delays in triage, code activation, imaging evaluations, and treatment. At our Comprehensive Stroke Center, 20% of patients with stroke have a Chinese dialect as a primary language and LEP. We sought to assess differences in stroke activation process times and IV alteplase treatment (IVT) rates between English and LEP (Chinese dialect) patients before and after implementation of a visual stroke symptom (VSS) triage tool.
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Lisa M. Scott Tags: Poster 02 Source Type: research

Dynamic Cerebral Autoregulation in Preclinical Atherosclerotic Cardiovascular Disease
Objective: The influence of atherosclerotic cardiovascular disease (ASCVD) on cerebral blood flow control is not well known. The aim of this study was to investigate the association between cardiovascular function and dynamic cerebral autoregulation (dCA) in patients with preclinical ASCVD. Methods: A total of 44 participants aged 26-76 years were divided into low- and high-risk groups according to the China assessment of ASCVD risk. The cardiac function was assessed by echocardiography. The beat-to-beat blood pressure and cerebral blood flow velocity were measured at rest.
Source: Journal of Stroke and Cerebrovascular Diseases - April 10, 2020 Category: Neurology Authors: Yumei Liu, Takashi Tarumi, Beibei Liu, Jingzhi Li, Xiaoguang Wu, Nan Zhang, Yang Hua Source Type: research

Association between Serum Lipid and Hematoma Expansion after Spontaneous Intracerebral Hemorrhage in Chinese Patients
Intracerebral hemorrhage (ICH) occurs in about 10%-20% of all stroke patients, and the overall incidence is approximately 25 of 100 000 per year1 and is expected to increase, given the increasing age of the population globally. Compared with ischemic stroke, ICH is correlated with a worse outcome, a mortality rate of around 40% and a dearth of effective treatments.1,2 It has been proven that serum lipid plays a vital role in the progression of cardiovascular disease and ischemic stroke.3 Nevertheless, the relationship between serum lipid concentrations and ICH remains unclear.
Source: Journal of Stroke and Cerebrovascular Diseases - March 26, 2020 Category: Neurology Authors: Bin Cai, Lin Peng, Zhi-bin Wang, Mei Zhang, Bin Peng Source Type: research

Left Atrial Enlargement is Associated with Stroke Severity with Cardioembolic and Cryptogenic Subtypes in a Chinese Population
In this study, we aim to evaluate the association between left atrial size and stroke severity, especially with cardioembolic and cryptogenic stroke in the Chinese population.
Source: Journal of Stroke and Cerebrovascular Diseases - March 11, 2020 Category: Neurology Authors: Jie Xue, Xu ‐shen Xu, Xiao‐qiong Zhu, Zhi‐zhang Li, Xiao-guang Zhang, Yan-ting Ma, Wen-hao Yang, Ling-yun Liu, Yun-hua Yue Source Type: research

Corrigendum to ’Comparison of Carotid Atherosclerosis between Patients at High Altitude and Sea Level: A Chinese Atherosclerosis Risk Evaluation Study’ Journal of Stroke and Cerebrovascular Diseases, Vol. 29, No. 2 (February), 2020: 104448
The authors regret that one of the author's name was misspelled at the time of the publication, thus the authors would like to correct it. Canto, GM should be replaced by Canton G.
Source: Journal of Stroke and Cerebrovascular Diseases - March 3, 2020 Category: Neurology Authors: Yuntai Cao, Xihai Zhao, Hiroko Watase, Daniel S. Hippe, Yousen Wu, Hongqian Zhang, Lina Yue, Gador Canton, Yan Song, Honglu Shi, Guangbin Wang, Rui Li, Haihua Bao, Chun Yuan, investigators of CARE-II study Tags: Corrigendum Source Type: research

A Comparative Study of Two Tube Feeding Methods in Patients with Dysphagia After Stroke: A Randomized Controlled Trial
Background: Dysphagia is a common symptom seen in stroke patients, it not only affects patients' nutrition supply, but also causes aspiration pneumonia. To solve the problem of nutritional support for patients with dysphagia after stroke, nasogastric tubes are routinely indwelling to provide nutrition in China. However, this feeding method sometimes causes food reflux, aspiration, pneumonia, and often affects the patients ’ comfort and self-image acceptance. Aim: The aim of this study was to determine whether a new feeding method called intermittent oroesophageal (IOE) tube feeding compared with continuous nasogastric tu...
Source: Journal of Stroke and Cerebrovascular Diseases - January 12, 2020 Category: Neurology Authors: Wei Juan, Huang Zhen, Feng Yan-Ying, Yang Hui-Xian, Zhong Tao, Guo Pei-Fen, Huo Jian-Tian Source Type: research

Comparison of Carotid Atherosclerosis between Patients at High Altitude and Sea Level: A Chinese Atherosclerosis Risk Evaluation Study
Objectives: To investigate the differences in characteristics of carotid plaques between patients Xining at high altitude and Jinan at sea level using magnetic resonance (MR) imaging. Methods: Subjects were recruited from a cross-sectional, observational, multicenter imaging study of CARE-II study. Forty-nine (mean age 63.3 ± 12.0 years, 33 males) and 51 (mean age 64.5 ± 12.0 years, 34 males) patients were recruited from a site located in a high altitude region and a site located near sea level, respectively.
Source: Journal of Stroke and Cerebrovascular Diseases - December 18, 2019 Category: Neurology Authors: Yuntai Cao, Xihai Zhao, Hiroko Watase, Daniel S. Hippe, Yousen Wu, Hongqian Zhang, Lina Yue, Gador M. Canto, Yan Song, Honglu Shi, Guangbin Wang, Rui Li, Haihua Bao, Chun Yuan, investigators of CARE-II study Source Type: research

Risk Stratification for Endovascular Treatment in Acute Anterior Circulation Occlusive Stroke
Objective: To develop and validate a novel scoring system for risk stratification in acute anterior circulation large vessel occlusion stroke patients undergoing endovascular treatment. Methods: Subjects were included from a multicenter registry on acute ischemic stroke undergoing thrombectomy in China. Two thirds of the patients were used as the derivation group and the other one third of the patients as the validation group. Multivariable logistic regression was used to generate the scoring system.
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2019 Category: Neurology Authors: Yunyun Xiong, Huaiming Wang, Meng Zhang, Zhiming Zhou, Wei Wang, Xinfeng Liu, Marc Fisher Source Type: research

Significant Stroke Knowledge Deficiencies in Community Physician Improved with Stroke 120
Background and Purpose: In the existing model of community health service in China, community general practitioners play important roles in health promotion as well as prehospital stroke recognition and management. We recently engineered Stroke 120 based on FAST for China. This investigation aimed to investigate its acceptance in community physicians and promote their stroke related knowledge. Methods: We conducted an stroke education session to community physicians or family doctors (total of 435 participants), teaching both FAST and Stroke 120.
Source: Journal of Stroke and Cerebrovascular Diseases - September 23, 2019 Category: Neurology Authors: Xiaochuan Liu, Yingfeng Weng, Renyu Liu, Jing Zhao Source Type: research

Predicting the Risk of Stroke in Chinese Internal Carotid Artery Stenosis Patients Underwent Carotid Artery Stenting: Validation and Improvement of Siena Carotid Artery Stenting Risk Score
Background: Siena carotid artery stenting (CAS) risk score is developed based on Chinese internal carotid artery (ICA) stenosis patients recruited in Italy, whether it is equally applicable in Chinese remains unknown. We aimed to investigate Siena CAS risk score value for predicting stroke risk in ICA stenosis patients underwent CAS and explore additional factors for improving accuracy of scoring system. Methods: Totally 401 patients with ICA stenosis who underwent CAS were enrolled. The clinical data (including patient characteristics, lesion features, and procedure-related features) were collected and the Siena CAS score was calculated.
Source: Journal of Stroke and Cerebrovascular Diseases - September 20, 2019 Category: Neurology Authors: Huchuan Zhou, Lin Shen, Fei Wei, Jie Shuai Source Type: research

A Case of Leukoencephalopathy and Small Vessels Disease Caused by a Novel HTRA1 Homozygous Mutation
Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL) is a heritable, rare small vessel disease, which is caused by HTRA1 mutations and mostly reported Japanese and Chinese population. CARASIL is an orphan disease, which presents with progressive motor and cognitive impairment, alopecia, and spondylosis. The disease typically starts with lumbago at early twenties. Ischemic strokes start at mid-twenties. Patients have no cardiovascular or any other risk factors.
Source: Journal of Stroke and Cerebrovascular Diseases - September 3, 2019 Category: Neurology Authors: Tuncay G ündüz, Yasemin Demirkol, Özlem Doğan, Serkan Demir, Nihan Hande Akçakaya Source Type: research

Determination of Clinical Cut-Off Values for Serum Cystatin C Levels to Predict Ischemic Stroke Risk
Background: The association between cystatin C and risk of ischemic stroke is inconsistent and the cut-off values of cystatin C are diverse in different articles. We aimed to investigate the association between cystatin C levels and the development of ischemic stroke and to explore the clinical cut-off values of serum cystatin C levels for ischemic stroke. Methods: This prospective cohort study included 7658 participants from the China Health and Retirement Longitudinal Study who were free of cardiovascular diseases and cancer at baseline.
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2019 Category: Neurology Authors: Youyi Wang, Ying Zhang, Qinghua Ma, Congju Wang, Yong Xu, Hongpeng Sun, Yana Ma Source Type: research

Imaging Classification of Internal Carotid Artery Hypoplasia Based on Distal Ophthalmic Segment Occlusion
Background: Internal carotid artery (ICA) hypoplasia (ICAH) is rare. The classification of ICAH is largely unclear. The aim of the study is to propose a new imaging classification for ICAH based on the occlusion of the distal ophthalmic segment and discuss the clinical and radiological differences between the different types. Materials and Methods: This was a retrospective study of patients with congenital ICAH diagnosed at the Department of Neurology of the China-Japan Friendship Hospital between June 2011 and June 2016.
Source: Journal of Stroke and Cerebrovascular Diseases - August 5, 2019 Category: Neurology Authors: Zhiyong Zhang, Zhiqin Liu, Zunjing Liu Source Type: research

Evaluating the Effect of Comprehensive Intervention on Cerebro-Vascular Function in Population at High Risk of Stroke
Background: Today there exists few intervention researches on cerebro-vascular function in populations at high risk of stroke in China. Methods: Patients more than 40 years old, with at least 1 of stroke risk factors were recruited from outpatient department in 3 hospitals. A quasi-experimental design was performed by assigning participants into 3 groups: comprehensive intervention group, health education group, and control group. Participants in the control group received no intervention but were informed of risk factors of stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - July 8, 2019 Category: Neurology Authors: Xiangxiang Liu, Yaohua Gu, Yuting Zhang, Yanan Zhang, Xiaodong Tan Source Type: research

Association Between Silent Brain Infarcts and Cognitive Function: A Systematic Review and Meta-Analysis
Background and Purpose: Silent brain infarct (SBI), which has traditionally been considered clinically silent, has been proposed as a subclinical risk marker for future cognitive function decline. Methods: We conducted a systematic review of literature in the Cochrane Library, MEDLINE, EMBASE, and the China National Knowledge Infrastructure database. Results: In the end, 19 case-control studies, comprising 6712 participants, and 3 prospective cohort studies comprising 4433 participants, met all inclusion criteria and were included in the systematic review.
Source: Journal of Stroke and Cerebrovascular Diseases - July 4, 2019 Category: Neurology Authors: Chunyan Lei, Qionghua Deng, Haijiang Li, Lianmei Zhong Tags: Review Article Source Type: research

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