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Social and health determinants related to adverse short-term outcomes after a first-ever stroke in adults younger than 65 years
Stroke-related mortality and disability-adjusted life years in adults younger than 65 have increased over the last decade. However, geographical differences in distributing these outcomes could reflect dissimilarity in determinants. Therefore, this cross-sectional study of secondary data from Chilean hospitals aims to analyze the association of sociodemographic and clinical factors with in-hospital case-fatality risk or acquired neurologic deficits (adverse outcomes) in inpatients aged 18 to 64 who experienced their first-ever stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - May 10, 2023 Category: Neurology Authors: Mauricio Lopez-Espejo, Rodrigo Poblete, Gabriel Bastias Source Type: research

The Impact of a Two-Year Long COVID-19 Public Health Restriction Program on Mechanical Thrombectomy Outcomes in a Stroke Network
The purpose of this study was to evaluate the impact of COVID-19 pandemic public health restrictions on our drip and ship mechanical thrombectomy program in Santiago Chile.
Source: Journal of Stroke and Cerebrovascular Diseases - April 17, 2023 Category: Neurology Authors: Rodrigo Rivera Source Type: research

Stroke symptoms, risk factors awareness and personal decision making in Chile. A national survey
Stroke is the second main cause of death and the first cause of acquired disability in the world.1 Even though there is a slight decrease in its incidence, DALYs and mortality rates in Latin America since 1990, the absolute numbers are increasing due to rapid population aging. In 2019 e there were 30,704 discharges of a new or recurrent stroke and 7,989 deaths related to stroke becoming the second main specific cause of death in Chile.23 Reperfusion therapy rates are low in Latin America,4-6 with many possible barriers including inequity in accessing complex systems of care for stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - October 15, 2022 Category: Neurology Authors: Victor Navia, Enrico Mazzon, Ver ónica V. Olavarría, Juan Almeida, Alejandro M. Brunser, Pablo M. Lavados, Lorena Hoffmeister, Paula Muñoz Venturelli Source Type: research

Breaking Down Barriers: Easter Island's First Telestroke Thrombolysis Experience and Case Report
Easter Island (Rapa Nui), Chile, is remote, located in the Polynesian Triangle in Oceania. The closest continental point is Chile, 3,512  km east. It has a population of 7,750 inhabitants, who are Chilean citizens, and receives more than 60,000 tourists a year. For this entire population, there is a medium complexity hospital without a neurology specialist. In 2019, local professionals were trained in a Telestroke program with remot e clinical support conducted by neurologists located on mainland Chile.
Source: Journal of Stroke and Cerebrovascular Diseases - March 27, 2022 Category: Neurology Authors: E. Mazzon, C. Delfino, S. Mirelis, M. Ar évalo, D. Rojas, L. Lara, D. Carcamo, F. Jurado, D. Rocha, P. Muñoz Venturelli, E. Mansilla Tags: Case Report Source Type: research

Impact of COVID-19 pandemic on stroke severity and mortality in the south-east of Santiago, Chile
Background and purpose: Chile has been one of the most affected countries by the COVID-19 pandemic, with one of the highest case rates per population. This has affected the epidemiological behaviour of various pathologies. We analyze the impact of the pandemic on the number of admissions due to stroke, its severity and mortality in Santiago, Chile.Methods: a multicenter observational study based on the records of the 3 hospitals of the South East health service in Santiago, Chile. We recorded the number of patients admitted for ischemic stroke between 01 January 2020 and 30 June 2020.
Source: Journal of Stroke and Cerebrovascular Diseases - June 18, 2021 Category: Neurology Authors: Andres Silva-Pozo, Jose Vallejos, Juan Almeida, Mariano Martoni, Reinaldo Uribe-San Martin, Mar ía Miranda, Pablo Diaz, Dominga García, Victor Navía Source Type: research

In-Hospital Acute Ischemic Stroke is Associated with Worse Outcome: Experience of a Single Center in Santiago Chile
In this study we aimed to identify the frequency of HIS and their characteristics in our center.
Source: Journal of Stroke and Cerebrovascular Diseases - June 9, 2021 Category: Neurology Authors: Alejandro Brunser, Victor Navia V, Patricia Araneda, Enrico Mazzon, Paula Mu ñoz, Gabriel Cavada, Verónica V. Olavarría, Pablo M. Lavados Source Type: research

Cervical Artery Dissections with and without stroke, risk factors and prognosis: a Chilean prospective cohort
We aimed to characterize spontaneous cervical artery dissection (CeAD) patients with and without stroke and describe risk factors for cerebrovascular complications in a Chilean prospective cohort.Methods: Consecutive CeAD patients admitted to a Chilean center confirmed by neuroimaging. Logistic regression was used.Results: 168 patients were included, median follow-up time was 157 days. Stroke occurred in 49 (29.2%) cases, 4 (2%) patients died, all of whom had a stroke, and 10 (6%) presented CeAD recurrence.
Source: Journal of Stroke and Cerebrovascular Diseases - July 15, 2020 Category: Neurology Authors: E. Mazzon, D. Rocha, A.M. Brunser, C. De la Barra, X. Stecher, T. Bernstein, P. Z úñiga, V. Díaz, G. Martínez, P. Muñoz Venturelli Source Type: research

NOTCH3 Gene Mutation in a Chilean Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy Family
We report the first Chilean CADASIL family with complete radiological and histological studies.
Source: Journal of Stroke and Cerebrovascular Diseases - December 5, 2019 Category: Neurology Authors: Andr és Gallardo, Verónica Latapiat, Alejandra Rivera, Beatriz Fonseca, Andrés Roldan, Patricio Sandoval, Carolina Sánchez, José Manuel Matamala Source Type: research

Association between Mapuche Ethnicity and Stroke: A Case-Control Study
Background: There is evidence of a greater incidence of stroke in native populations and minorities. A total of 34% of the population in the Araucan ía Region is indigenous. The association between Mapuche ethnicity and stroke is unknown. The aim of the study was to estimate the magnitude of the association between Mapuche ethnicity and stroke occurrence in patients admitted to the Dr. Hernán Henríquez Aravena Hospital (HHHA) in Temuco, Chile . Methods: We performed an incident case–control-paired study with patients hospitalized with an acute stroke in the internal medicine service and controls from other medical services at the HHHA.
Source: Journal of Stroke and Cerebrovascular Diseases - February 13, 2019 Category: Neurology Authors: Álvaro Soto, Gladys Morales, Rosa Provoste, Fernando Lanas, Isabel Aliaga, Daniela Pacheco, Sergio Muñoz Source Type: research

Prevalence and Predictors of Long-Term Functional Impairment, Epilepsy, Mortality, and Stroke Recurrence after Childhood Stroke: A Prospective Study of a Chilean Cohort
To evaluate the prevalence and predictors of long-term impairment, epilepsy, mortality, and recurrences after the first stroke in a cohort of Chilean children.
Source: Journal of Stroke and Cerebrovascular Diseases - May 2, 2017 Category: Neurology Authors: Mauricio L ópez-Espejo, Marta Hernández-Chávez Source Type: research

Short- and Long-term Survival after Stroke in Hospitalized Patients in Chile: A Nationwide 5-Year Study
Conclusions: Short- and long-term survival after ischemic stroke was heterogeneous by geographic regions and type of health insurance, regardless age and sex were the strongest predictors. This suggests an impact of socioeconomic factors and access to acute management of strokes on survival.
Source: Journal of Stroke and Cerebrovascular Diseases - June 10, 2013 Category: Neurology Authors: Lorena Hoffmeister, Pablo M. Lavados, Cristiane Murta-Nascimento, Miguel Araujo, Verónica V. Olavarría, Xavier Castells Tags: Original Articles Source Type: research

Long-term Adherence to National Guidelines for Secondary Prevention of Ischemic Stroke: A Prospective Cohort Study in a Public Hospital in Chile
Conclusions: The observed significant decrease in adherence to oral anticoagulation in patients with cardioembolic stroke suggests a need for the implementation of specific strategies to achieve the desired secondary prevention goals in these patients. Future research into the evaluation of other factors that could be associated with the lack of adherence to these guidelines, measurements of therapeutic goals, and new therapeutic strategies that are easier to use and that are associated with less risk could improve the prognosis of these patients.
Source: Journal of Stroke and Cerebrovascular Diseases - May 15, 2013 Category: Neurology Authors: Paula Muñoz-Venturelli, Claudio Sacks, Eva Madrid, Pablo M. Lavados Tags: Original Articles Source Type: research