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Body mass index and waist circumference as predictors of recurrent vascular events after a recent ischemic stroke
Obesity is an independent contributor to ischemic stroke incidence. A meta-analysis of 13 studies revealed that a 5 kg/m2 increase in body mass index (BMI) was associated with a 22% increased risk of ischemic stroke in European/North American/Australian cohorts and a 35% increased risk of ischemic stroke among the Asian populations.1 In a meta-analysis of 7 prospective studies, persons in the highest waist circumference (WC) category had a relative risk of 1.41 (95% CI, 1.21 ⁠–1.56) for ischemic stroke compared with persons in the lowest category.
Source: Journal of Stroke and Cerebrovascular Diseases - July 11, 2023 Category: Neurology Authors: Kyusik Kang, Jong-Moo Park, Wi-Sun Ryu, Sang-Wuk Jeong, Dong-Eog Kim, Hong-Kyun Park, Yong-Jin Cho, Keun-Sik Hong, Kyung Bok Lee, Tai Hwan Park, Sang-Soon Park, Juneyoung Lee, Beom Joon Kim, Moon-Ku Han, Hee-Joon Bae Source Type: research

Additional therapy promotes a continued pattern of improvement in upper-limb function and independence post-stroke
Stroke is considered a major worldwide health issue, and one of the leading causes of acquired disability in Australia, leading to lifelong impairment or death.1 Better recognition, management and medical treatment of acute stroke events have led to a reduction in both mortality2 and the severity of post-stroke impairments. The corollary of this sustained improvement in post-stroke outcomes is the growing number of survivors in the chronic phase living in the community and in need of ongoing rehabilitation, shifting our view towards stroke as a chronic disease rather than a single, neurological event.
Source: Journal of Stroke and Cerebrovascular Diseases - January 19, 2023 Category: Neurology Authors: AG Thompson-Butel, SK Ashcroft, G Lin, T Trinh, PA McNulty Source Type: research

Factors associated with delay to carotid endarterectomy for acute ischaemic stroke in South Australia: A multicentre retrospective cohort study
The greatest benefits of carotid endarterectomy (CEA) accrue when performed within two weeks of acute ischaemic stroke (AIS) due to symptomatic carotid stenosis. Previous studies have identified multiple factors contributing to CEA delay.
Source: Journal of Stroke and Cerebrovascular Diseases - December 22, 2022 Category: Neurology Authors: Rudy Goh, Stephen Bacchi, Joshua G. Kovoor, Aashray K. Gupta, Minh-Son To, Christopher D. Ovenden, Joseph Dawson, Wilson Vallat, David Schultz, Jim Jannes, Timothy Kleinig Source Type: research

Transition in Incidence Rate of Hospitalised Stroke and Case Fatality Rate in the Hunter Region, Australia, 2001-2019: A Prospective Hospital-Based Study
Introduction: Continuous surveillance of stroke admissions has been conducted in the Hunter region, Australia, over the past two decades. We aimed to describe the trends in incidence rates of hospitalised stroke and case-fatality rates in this region, 2001-2019. Methods: From a hospital-based stroke registry, data for admitted adult stroke patients residing in the Hunter region were collected using ICD-10 codes for ischemic and haemorrhagic stroke. Negative binomial regression and logistic regression analysis were used to analyse trends for age-standardised and age-specific incidence rates of hospitalised stroke and 28-day...
Source: Journal of Stroke and Cerebrovascular Diseases - February 3, 2022 Category: Neurology Authors: Yumi Tomari Kashida, Thomas Lillicrap, Rhonda Walker, Elizabeth Holliday, Md Golam Hasnain, Shinya Tomari, Carlos Garcia-Esperon, Jennifer J. Majersik, Neil J. Spratt, Christopher Levi Source Type: research

Denial of Cerebrovascular Events in a National Clinical Quality Registry for Stroke: A Retrospective Cohort Study
To investigate cerebrovascular event (CVE) denials reported by registered patients to the Australian Stroke Clinical Registry, and to examine the factors associated with CVE denial.
Source: Journal of Stroke and Cerebrovascular Diseases - December 2, 2021 Category: Neurology Authors: Karen M. Barclay, Monique F. Kilkenny, Sibilah J. Breen, Olivia F. Ryan, Kathleen L. Bagot, Natasha A. Lannin, Vincent Thijs, Dominique A. Cadilhac, AuSCR Consortium Source Type: research

Cost Burden and Cost-Effective Analysis of the Nationwide Implementation of the Quality in Acute Stroke Care Protocol in Australia
Stroke is the third global leading cause of death and disability.1,2 In Australia, stroke accounts for 3% of the total burden of disease and 5% of all deaths, with 36,700 incident strokes annually.3 Healthcare expenditure for stroke in Australia in 2017 was AUD 663 million.4
Source: Journal of Stroke and Cerebrovascular Diseases - June 19, 2021 Category: Neurology Authors: Clara Marquina, Zanfina Ademi, Ella Zomer, Richard Ofori-Asenso, Rhiannon Tate, Danny Liew Source Type: research

Age-Related Disparities in the Quality of Stroke Care and Outcomes in Rehabilitation Hospitals: The Australian National Audit
Stroke is a life-changing event affecting survivors, their families, communities and workplaces. About 75% of strokes occur in people 65 years or older,1 but the incidence is increasing in those aged 20-64,2,3 during the most productive years of people's live. This contributes substantially to the social and economic burden of stroke to society.2,4 Specialist inpatient rehabilitation is cost effective in working age adults, even with complex neurological conditions such as stroke.5 The characteristics and rehabilitative needs often differ between younger and older survivors of stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - March 16, 2021 Category: Neurology Authors: Tara Purvis, Isobel J Hubbard, Dominique A Cadilhac, Kelvin Hill, Justine Watkins, Natasha A. Lannin, Steven G Faux, Monique F Kilkenny Source Type: research

Occlusive Disease and Upright Activity in Acute Ischemic Stroke
The impact of out-of-bed upright activity on outcomes in ischemic stroke patients with severe extra- and intracranial stenosis or occlusion is unknown. Using ultrasound findings from a cohort recruited to A Very Early Rehabilitation Trial (AVERT) which compared higher dose very early mobilisation (VEM) to usual care (UC), we aimed to explore the association between occlusive disease and 3-month outcomes and occlusive disease-by-mobilisation treatment interactions. Participants with ischemic stroke, with carotid and transcranial Doppler ultrasounds performed ≤1 week after admission, were included in this single centre sub...
Source: Journal of Stroke and Cerebrovascular Diseases - January 19, 2021 Category: Neurology Authors: Lilian B. Carvalho, Brian Chambers, Karen Borschmann, Tina Kaffenberger, Leonid Churilov, Vincent Thijs, Julie Bernhardt, AVERT trial collaboration group Source Type: research

Factors Associated with Stroke Coding Quality: A Comparison of Registry and Administrative Data
The International Statistical Classification of Diseases and Related Health Problems, 10th Revision, Australian Modification (ICD-10-AM) codes are commonly used to identify patients with diseases or clinical conditions for epidemiological research. We aimed to determine the diagnostic agreement and factors associated with a clinician-assigned stroke diagnosis in a national registry and the ICD-10-AM codes recorded in government-held administrative data.
Source: Journal of Stroke and Cerebrovascular Diseases - November 27, 2020 Category: Neurology Authors: Olivia F. Ryan, Merilyn Riley, Dominique A. Cadilhac, Nadine E. Andrew, Sibilah Breen, Kate Paice, Sam Shehata, Vijaya Sundararajan, Natasha A. Lannin, Joosup Kim, Monique F. Kilkenny Source Type: research

Exploring the Economic Benefits of Modafinil for Post-Stroke Fatigue in Australia: A Cost-Effectiveness Evaluation
Post-stroke fatigue remains a substantial ‘silent disability’, affecting up to three-quarters of stroke survivors,1,2 and rating among the worst symptoms experienced by nearly half of stroke survivors.3 On the spectrum of stroke complications, fatigue receives considerably less attention than more visible physical disabilities,4 despite fatigue adversely affecting clinical outcomes and quality of life, and being an independent predictor of institutionalisation, dependence in activities of daily living, poorer functional outcomes, and death.
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2020 Category: Neurology Authors: Beata Bajorek, Lan Gao, Tom Lillicrap, Andrew Bivard, Carlos Garcia-Esperon, Mark Parsons, Neil Spratt, Elizabeth Holliday, Chris Levi Source Type: research

Incidence of Hospitalization for Stroke in Queensland, Australia: Younger Adults at Risk
Background: Trends in the incidence of stroke are important for health care planning. Information is particularly scarce in Australia, due to the paucity of studies with access to recent, large-scale, longitudinal datasets. In this paper we investigated the incidence of hospitalization for stroke by sex, age, and subtype in the whole State of Queensland (Australia). Methods: We obtained data of all hospital admissions for stroke in Queensland from 2002 to 2015. Age standardized hospitalization rates for first-ever stroke were calculated along with WHO adjusted rates.
Source: Journal of Stroke and Cerebrovascular Diseases - April 8, 2020 Category: Neurology Authors: Deanna Anderlini, Guy Wallis, Welber Marinovic Source Type: research

Augmented Performance Feedback during Robotic Gait Therapy Results in Moderate Intensity Cardiovascular Exercise in Subacute Stroke
Low cardiovascular fitness is common poststroke. Conventional subacute stroke rehabilitation does not meet Australian National Stroke Guidelines for cardiovascular exercise, particularly in mobility-dependent patients. Walking robotics can potentially achieve recommended cardiovascular exercise with these patients.
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2020 Category: Neurology Authors: Nicole Prideaux, Maayken van den Berg, Claire Drummond, Christopher Barr Source Type: research

Outcomes for Patients With In-Hospital Stroke: A Multicenter Study From the Australian Stroke Clinical Registry (AuSCR)
The quality of care and outcomes for people who experience stroke whilst in hospital for another condition has not been previously studied in Australia.
Source: Journal of Stroke and Cerebrovascular Diseases - February 26, 2019 Category: Neurology Authors: Dominique A. Cadilhac, Monique F. Kilkenny, Natasha A. Lannin, Helen M. Dewey, Christopher R. Levi, Kelvin Hill, Brenda Grabsch, Rohan Grimley, David Blacker, Amanda G. Thrift, Sandy Middleton, Craig S. Anderson, Geoffrey A. Donnan, On behalf of the Austr Source Type: research

Television Viewing Time and Stroke Risk: Australian Diabetes Obesity and Lifestyle Study (1999-2012)
Introduction: Having a low level of physical activity is an established risk factor for stroke, but little is known about the importance of common sedentary behavior —television viewing—to stroke risk. Methods: We conducted a retrospective analysis of data that were collected as part of the longitudinal Australian Diabetes, Obesity, and Lifestyle study. Stroke events reported during the study (between baseline assessment in 1999-2000 and April 2011) were con firmed using adjudication based on medical records.
Source: Journal of Stroke and Cerebrovascular Diseases - January 22, 2019 Category: Neurology Authors: Toby B. Cumming, Elizabeth Holliday, David Dunstan, Coralie English Source Type: research