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EP 121. Motor sequence learning in patients with limb apraxia – The effects of long-term training
Recent studies show that limb apraxia is often not recognized as a higher motor impairment in patients suffering from a stroke. Because it is adversely affecting every-day life and personal independence, a successful rehabilitation of apraxia is critical for personal well-being (Cappa et al., 2005; Dovern et al., 2012). Yet, evidence of an effective treatment approach with long-lasting effects and generalization to untrained actions is still missing (Binkofski and Klann, 2013; Dovern et al., 2011).
Source: Clinical Neurophysiology - August 5, 2016 Category: Neuroscience Authors: S. Reitze, M. Heister über, A. Karni, C. Gal, J. Doyon, B.R. King, J. Classen, J.- J. Rumpf, G. Buccino, J. Klann, F. Binkofski Source Type: research

EP 84. Motor control and learning strategy for efficient neurorehabilitation
Parkinson ’s, stroke, and other neurological diseases may significantly affect the control of voluntary, ballistic-like movements that normally are performed automatically and optimally as regards position accuracy, energy expenditure and movement execution time. The control functions (neural signals to mus cles) are to be re-learnt and re-optimised with respect to these performance indices. In our study, a natural approach for efficient motor learning in goal-directed motion tasks, incl. walking is proposed.
Source: Clinical Neurophysiology - August 5, 2016 Category: Neuroscience Authors: D. Despotova, P. Kiriazov Tags: ePoster Presentations – Free Topics Source Type: research

P 68 Novel control concepts and motor re-learning strategy in neurorehabilitation – practically-oriented approach
Persons suffering from functional impairment, due to cerebral palsy, stroke, or Parkinson ’s, often have not reached their full potential for recovery which often is a reason for injures and loss of life due to fall. Motor skill learning and retention of motor skills can be enhanced if a patient assumes control over practice conditions, e.g. timing of exercise instructions and feedback . In our study, we follow a novel conceptual framework (Despotova and Kiriazov, 2015) for optimal control learning of goal-directed motion tasks, like reaching, standing up and walking.
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: D. Despotova, P. Kiriazov Tags: Poster Source Type: research

S3-2. Rewiring of a damaged neural pathway via a neural interface induces targeted reorganization of an extensive cortical area
Regaining the function of an impaired limb is highly desirable in individuals experiencing paralysis. One possible avenue to achieve this goal is through rewiring of preserved neural structures to bridge the interrupted pathway using a brain-computer interface. Here we demonstrated that monkeys with subcortical stroke were able to learn to use an artificial cortico-muscular connection (ACMC), brain-controlled functional electrical stimulation to the hand muscles, to regain volitional control of a paralyzed hand.
Source: Clinical Neurophysiology - March 30, 2018 Category: Neuroscience Authors: Kenji Kato, Masahiro Sawada, Yukio Nishimura Source Type: research

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