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Source: Clinical Neurophysiology
Drug: Baclofen

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Intrathecal Baclofen Bolus Reduces Exaggerated Extensor Coactivation during Pre-Swing and Early-Swing of Gait after Acquired Brain Injury
Pathological muscle activation patterns during gait are common after acquired brain injury (ABI). In an early study of 26 stroke patients, Knutsson and Richards (1979) monitored the hip abductor, hip adductors, quadriceps, hamstrings, triceps surae, and tibialis anterior (TA) muscles and qualitatively described 3 different patterns of abnormal muscle activation during gait, one of which is characterized by coactivation of several muscle groups during the end of swing and throughout the main part of the stance phase.
Source: Clinical Neurophysiology - February 28, 2017 Category: Neuroscience Authors: John W. Chow, Stuart A. Yablon, Dobrivoje S. Stokic Source Type: research