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The Effects of Botulinum Toxin Injections on Plantar Flexor Spasticity in Different Phases After Stroke: A Secondary Analysis From a Double-Blind, Randomized Trial
There are no guidelines on the ideal time to inject botulinum toxin type A (BT-A) for lower leg spasticity in stroke patients. An early injection may produce unwanted weakness, interfering with gait recovery.
Source: PM and R - March 3, 2018 Category: Rehabilitation Authors: Hyun-Mi Oh, Geun-Young Park, Young Min Choi, Hyung Jung Koo, Yongjun Jang, Sun Im Tags: Original Research Source Type: research

Poster 307: Non-Rhythmic Recurrent Shaking After Right Basal Ganglia Stroke: A Case Report
Aaron Hanyu-Deutmeyer: My spouse/partner has a relationship with Allergan Speakers bureau, My spouse/partner has a relationship with Allergan provided Botox for injection
Source: PM and R - September 1, 2017 Category: Rehabilitation Authors: Aaron A. Hanyu-Deutmeyer, Padma K. Srigiriraju Source Type: research

Therapeutic Synergism in the Treatment of Post-stroke Arm Paresis Utilizing Botulinum Toxin, Robotic Therapy, and Constraint-induced Movement Therapy
Botulinum toxin type A (BtxA) injection, constraint-induced movement therapy (CIMT), and robotic therapy (RT) each represent promising approaches to enhance arm motor recovery after stroke. To provide more effective treatment for a 50-year-old man with severe left spastic hemiparesis, we attempted to facilitate CIMT with adaptive approaches to extend the wrist and fingers using RT for 10 consecutive weeks after BtxA injection. This combined treatment resulted in substantial improvements in arm function and the amount of arm use in activities of daily living, and may be effective for stroke patients with severe arm paresis.
Source: PM and R - May 28, 2014 Category: Rehabilitation Authors: Takashi Takebayashi, Satoru Amano, Keisuke Hanada, Atsushi Umeji, Kayoko Takahashi, Tetsuo Koyama, Kazuhisa Domen Tags: Case Presentation Source Type: research

Balancing Burdens and Benefits: Ethical Issues of Off-Label Prescription Pharmaceutical Use
I remember when Botox (Allergen, Irvine, CA) was becoming all the rage in rehabilitation in the mid 1990s. As I recall, the only U.S. Food and Drug Administration (FDA) approved uses at the time were for spasmodic torticollis and blepharospasm. In a short period of time, however, Botox was the new treatment du jour for adults and children alike with spasticity from CP, traumatic brain injury (TBI), and stroke. I also remember feeling a bit queasy about it. Perhaps having recently completed a fellowship in clinical medical ethics colored my view. Images of thousands of people with limb deficiencies, the tragic consequence ...
Source: PM and R - October 1, 2013 Category: Rehabilitation Authors: Ford Vox, Alexander M. Capron, Marilyn F. Kraus, G. Caleb Alexander, Kristi L. Kirschner Tags: Ethical Legal Source Type: research