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Abstract #140: BDNF Genotype and tDCS Interaction in Aphasia Therapy
Introduction: Using a double blinded randomized controlled trial, we evaluated the extent to which brain stimulation (anodal transcranial direct current stimulation [A-tDCS]) applied during speech therapy, was a futile adjunctive intervention to improve speech production (naming) in individuals with chronic post-stroke aphasia. This futility design evaluated a null hypothesis of 'A-tDCS results in better treatment outcome than sham tDCS.'
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: Julius Fridriksson, Jordan Elm, Brielle C. Stark, Alexandra Basilakos, Chris Rorden, Souvik Sen, Mark George, Leonardo Bonilha Source Type: research

The efficacy of selective transcranial magnetic stimulation with functional near-infrared spectroscopy and intensive speech therapy on individuals with post-stroke aphasia
Introduction: To examine the efficacy of selective repetitive transcranial magnetic stimulation (rTMS) therapy guided by functional near-infrared spectroscopy (fNIRS) combined with intensive speech therapy(ST) on post-stroke patients with aphasia, and right hemisphere high-frequency rTMS combined with intensive ST on patients who were right hemisphere-activated in a language task.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 15, 2017 Category: Neurology Authors: T. Hara, M. Abo, K. Kakita Source Type: research

Can enhancing left lateralization using transcranial direct current stimulation improve recovery from post-stroke aphasia?
One third of stroke victims suffer from aphasia, an acquired language disorder for which there are few effective medical treatments. Aphasia often does not resolve completely, resulting in substantial long-term disability. After a stroke that causes aphasia, the reorganization of language networks in the brain involves compensatory recruitment of brain tissue in the left hemisphere as well as potentially maladaptive recruitment of symmetric areas in the right hemisphere. One avenue for intervention might be to externally “left lateralize” the brain, enhancing activity of the left frontal lobe while inhibiting the right...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 1, 2014 Category: Neurology Authors: Mackenzie Fama, Elizabeth Lacey, Alexa Desko, Lauren Taylor, Laura Hussey, Peter Turkeltaub Tags: Abstracts Presented at NYC Neuromodulation 2013 Source Type: research