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Safety, tolerability and feasibility of remotely-instructed home-based transcranial direct current stimulation in children with cerebral palsy
Perinatal stroke or brain bleeds affect an estimated 1 in 3500 births in the United States, with an increased risk of developing cerebral palsy (CP), a developmental disorder associated with motor impairment [1,2]. While many CP rehabilitation approaches emphasize behavioral repetition to improve gait and upper extremity function, these therapies are costly, restricted to the clinic, and may offer limited functional gains [3]. Therefore, innovative rehabilitation strategies which are accessible, cost-effective, and time-efficient are indicated for long-term benefits.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - August 29, 2023 Category: Neurology Authors: Preston Christopher, Ellen Sutter, Marissa Gavioli, Daniel H. Lench, Gwendolyn Nytes, Veronika Mak, Emma A. Simpson, Chrysanthy Ikonomidou, Melissa A. Villegas, Catarina Saiote, Bernadette T. Gillick Source Type: research

Transcranial magnetic stimulation to assess motor neurophysiology after acute stroke in the United States: Feasibility, lessons learned, and values for future research
Transcranial magnetic stimulation (TMS) has been widely applied in both basic and clinical neuroscience since its introduction in 1985. In addition to its potential therapeutic value for exciting or inhibiting neural circuits [1], TMS can be used to investigate corticomotor excitability (CME), which is a key aspect of voluntary movement [2]. For example, single-pulse TMS can elicit electrical signals, which propagate along descending motor pathways and are recorded as motor evoked potentials (MEP) in target muscles.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - December 6, 2021 Category: Neurology Authors: Yi-Ling Kuo, David J. Lin, Isha Vora, Julie A. DiCarlo, Dylan J. Edwards, Teresa J. Kimberley Source Type: research

Abstract #7: HD-tDCS to contralesional hemisphere to enhance treatment outcomes in persons with stroke-induced aphasia
Background: Chronic aphasia, or language difficulty persisting beyond one year post-stroke, affects over 2.5 million individuals in the United States. Treatment response varies and language abilities are rarely restored. Intact, connected ipsilesional language areas and improved interhemispheric balance following stroke are consistent predictors of recovery. A promising approach to target these brain dynamics is using high-definition transcranial direct current stimulation (HD-tDCS) to deliver focal cathodal current to right frontal areas in the contralesional hemisphere, combined with efficacious behavioral treatment that...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: J.D. Richardson, S.G.H. Dalton, J.F. Cavanagh, C. Shultz, J. Adams Source Type: research