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Abstract #140: BDNF Genotype and tDCS Interaction in Aphasia Therapy
Introduction: Using a double blinded randomized controlled trial, we evaluated the extent to which brain stimulation (anodal transcranial direct current stimulation [A-tDCS]) applied during speech therapy, was a futile adjunctive intervention to improve speech production (naming) in individuals with chronic post-stroke aphasia. This futility design evaluated a null hypothesis of 'A-tDCS results in better treatment outcome than sham tDCS.'
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: Julius Fridriksson, Jordan Elm, Brielle C. Stark, Alexandra Basilakos, Chris Rorden, Souvik Sen, Mark George, Leonardo Bonilha Source Type: research

Transcranial direct current stimulation to treat aphasia: Longitudinal analysis of a randomized controlled trial
Post-stroke aphasia is a pervasive language disorder that affects communication and quality of life. Behavioral aphasia therapy is currently standard of care; however, in the chronic phase of recovery (>6 months post stroke), gains are often minimal. A number of studies have suggested that active transcranial direct current stimulation (A-tDCS) may improve treatment outcomes when coupled with behavioral aphasia therapy. However, many of these studies included small sample sizes or only single cases.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - September 29, 2018 Category: Neurology Authors: Julius Fridriksson, Alexandra Basilakos, Brielle C. Stark, Chris Rorden, Jordan Elm, Michelle Gottfried, Mark S. George, Souvik Sen, Leonardo Bonilha Source Type: research