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Source: The Journal of Clinical Endocrinology and Metabolism

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Total 115 results found since Jan 2013.

Diabetes, myocardial infarction and stroke are distinct and duration-dependent predictors of subsequent cardiovascular events and all-cause mortality in older men.
Conclusions: In older men, increasing duration of diabetes predicts stable increases in all-cause and MI-related mortality and a progressively higher risk of stroke deaths. Prior MI was associated with increased risk of subsequent MI, and prior stroke with subsequent stroke, particularly in the 10-20 years following the first event. Diabetes is a duration-dependent risk factor for cardiovascular events which influences outcomes differently from prior vascular disease. PMID: 25548977 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - December 30, 2014 Category: Endocrinology Authors: Yeap BB, McCaul KA, Flicker L, Hankey GJ, Almeida OP, Golledge J, Norman PE Tags: J Clin Endocrinol Metab Source Type: research

Exposure to maternal gestational diabetes is associated with higher cardiovascular responses to stress in adolescent Indians.
Conclusions: Maternal diabetes during pregnancy is associated with higher cardio-sympathetic stress-responses in the offspring, which may contribute to their higher cardiovascular disease risk. Further research may confirm stress-response programming as a predictor of cardiovascular risk in OGDM. PMID: 25478935 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - December 5, 2014 Category: Endocrinology Authors: Krishnaveni GV, Veena SR, Jones A, Srinivasan K, Osmond C, Karat SC, Kurpad AV, Fall CH Tags: J Clin Endocrinol Metab Source Type: research

Insulin resistance and beat-to-beat cardiovascular dynamics: a constant relationship across different body mass index and blood pressure categories.
Conclusions: These findings indicate that even small increases in HOMA index (not necessarily in the range to define insulin resistance) may induce significant changes on indices of cardiovascular function even in normal weight and normotensive subjects, emphasizing the importance of insulin resistance at an early stage of the cardiovascular risk continuum. PMID: 25329765 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - October 20, 2014 Category: Endocrinology Authors: Eugenio Ochoa J, Alberto Gallo J, Maria Correa M, Zapata N, Guillermo McEwen J, Bilo G, Aristizabal D, Parati G Tags: J Clin Endocrinol Metab Source Type: research

In older men, higher plasma testosterone or dihydrotestosterone are independent predictors for reduced incidence of stroke but not myocardial infarction.
Conclusions: Higher plasma T or DHT are biomarkers for reduced risk of stroke but not MI. Androgen exposure may influence outcomes following rather than incidence of MI, while androgens but not E2 are independent predictors of stroke risk. Randomised clinical trials are needed to clarify the impact of modifying T or DHT on the risk of stroke in ageing men. PMID: 25268392 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - September 30, 2014 Category: Endocrinology Authors: Yeap BB, Alfonso H, Paul Chubb SA, Hankey GJ, Handelsman DJ, Golledge J, Almeida OP, Flicker L, Norman PE Tags: J Clin Endocrinol Metab Source Type: research

Obstructive Sleep Apnea and Risk of Osteoporosis: A Population-Based Cohort Study in Taiwan.
Conclusion: People diagnosed with OSA are at increased risk for subsequent osteoporosis. PMID: 24735427 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - April 15, 2014 Category: Endocrinology Authors: Chen YL, Weng SF, Shen YC, Chou CW, Yang CY, Wang JJ, Tien KJ Tags: J Clin Endocrinol Metab Source Type: research

Hyperandrogenic Oligomenorrhea and Metabolic Risks Across Menopausal Transition.
CONCLUSIONS: Longitudinal evidence suggests that a history of androgen excess and menstrual irregularity is not associated with worsening of metabolic health after menopause. Our findings challenge the notion that a history of concurrent HA and Oligo reflects ongoing cardiometabolic risk in postmenopausal women. PMID: 24517154 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - February 11, 2014 Category: Endocrinology Authors: Polotsky AJ, Allshouse AA, Crawford SL, Harlow SD, Khalil N, Kazlauskaite R, Santoro N, Legro RS Tags: J Clin Endocrinol Metab Source Type: research

Serum 25-hydroxyvitamin D and incidence of fatal and non-fatal cardiovascular events: A prospective study with repeated measurements.
Conclusions:Our results support evidence that low 25(OH)D levels are associated with moderately increased risk of CVD and indicate that the observed association is much stronger for fatal than for non-fatal events. PMID: 24106288 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - October 8, 2013 Category: Endocrinology Authors: Perna L, Schöttker B, Holleczek B, Brenner H Tags: J Clin Endocrinol Metab Source Type: research

Long-term Cardio- and Cerebro-Vascular Events in Patients with Primary Aldosteronism.
Conclusions:this study demonstrate in a large population of patients the pathogenetic role of aldosterone excess in the cardiovascular system and thus the importance of early diagnosis and targeted PA treatment. PMID: 24057288 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - September 20, 2013 Category: Endocrinology Authors: Mulatero P, Monticone S, Bertello C, Viola A, Tizzani D, Iannaccone A, Crudo V, Burrello J, Milan A, Rabbia F, Veglio F Tags: J Clin Endocrinol Metab Source Type: research

Blood Pressure and Stroke Risk among Diabetic Patients.
Conclusions:The current study suggests a U-shaped association between blood pressure and the risk of stroke. Aggressive BP control (<110/65 mmHg) and high blood pressure (≥160/100 mmHg) are associated with an increased risk of stroke among both African American and white patients with type 2 diabetes. PMID: 23714680 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - May 28, 2013 Category: Endocrinology Authors: Zhao W, Katzmarzyk PT, Horswell R, Wang Y, Johnson J, Cefalu WT, Ryan DH, Hu G Tags: J Clin Endocrinol Metab Source Type: research

Mortality and Other Important Diabetes-Related Outcomes With Insulin vs Other Antihyperglycemic Therapies in Type 2 Diabetes.
Conclusions: In people with T2DM, exogenous insulin therapy was associated with an increased risk of diabetes-related complications, cancer, and all-cause mortality. Differences in baseline characteristics between treatment groups should be considered when interpreting these results. PMID: 23372169 [PubMed - in process]
Source: The Journal of Clinical Endocrinology and Metabolism - February 1, 2013 Category: Endocrinology Authors: Currie CJ, Poole CD, Evans M, Peters JR, Morgan CL Tags: J Clin Endocrinol Metab Source Type: research