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Efficacy of a family-based cardiovascular risk reduction intervention in individuals with a family history of premature coronary heart disease in India (PROLIFIC): an open-label, single-centre, cluster randomised controlled trial
Lancet Glob Health. 2021 Oct;9(10):e1442-e1450. doi: 10.1016/S2214-109X(21)00319-3.ABSTRACTBACKGROUND: Coronary heart disease, a leading cause of death globally, is amenable to lifestyle interventions. The family environment can affect the ability or willingness of individuals to make lifestyle changes. We aimed to investigate the efficacy of a targeted family-based intervention for reduction of total cardiovascular risk in individuals with a family history of premature coronary heart disease.METHODS: We did an open-label, cluster randomised controlled trial (PROLIFIC) in the families (first-degree relatives and spouses, o...
Source: Australian Family Physician - September 17, 2021 Category: Primary Care Authors: Panniyammakal Jeemon Sivadasanpillai Harikrishnan Sanjay Ganapathi Sivasubramonian Sivasankaran Bhaskarapillai Binukumar Sandosh Padmanabhan Nikhil Tandon Dorairaj Prabhakaran Source Type: research

Factors affecting general practitioners' decisions to adopt new prescription drugs - cohort analyses using Australian longitudinal physician survey data.
CONCLUSIONS: Our paper is one of the first to study the relationship between GPs' risk preferences, personality and their decisions to adopt new prescription drugs. Because NOACs are commonly prescribed and considered more cost-effective than their older counterpart, understanding factors affecting physicians' decisions to adopt NOACs has direct policy implications. Our results also highlight that even with universal coverage for prescription drugs, access to new drugs is different among patients, partially because who their doctors are and where they practice. PMID: 30728010 [PubMed - in process]
Source: Australian Family Physician - February 7, 2019 Category: Primary Care Authors: Zhang Y, Méndez SJ, Scott A Tags: BMC Health Serv Res Source Type: research

Obstructive sleep apnoea and obesity.
The objectives of this article are to review the interactions between obesity and OSA, including the increased cardiovascular risk, and highlight the importance of using OSA diagnosis as a critical time to address obesity itself and other cardiovascular risk factors. DISCUSSION: Snoring and symptoms of OSA frequently worsen during periods of rapid weight gain. Obesity and metabolic factors (eg hypertension, hyperlipidaemia, insulin resistance) are commonly present at the time of OSA diagnosis. Severe OSA is an independent risk factor for cardiovascular disease and stroke. Continuous positive airway pressure (CPAP) tre...
Source: Australian Family Physician - July 13, 2017 Category: Primary Care Authors: Hamilton GS, Joosten SA Tags: Aust Fam Physician Source Type: research

Surgery for adult patients with obstructive sleep apnoea: A review for general practitioners.
This article presents an overview of the surgical options available for OSA. The review also describes a useful approach for selecting appropriate patients for surgery. DISCUSSION: On the basis of an OSA model that accounts for observed increased risk of stroke, cardiovascular disease and motor vehicle accidents, there is evidence to support that surgery is beneficial and cost-effective for patients with severe OSA who are intolerant of CPAP. There are many surgical options available for OSA. PMID: 27610447 [PubMed - in process]
Source: Australian Family Physician - July 31, 2016 Category: Primary Care Authors: Phan NT, Wallwork B, Panizza B Tags: Aust Fam Physician Source Type: research

French Intensive Care Society, International congress - Réanimation 2016.
C, Sauneuf B, Verrier P, Pottier V, Orabona M, Samba D, Viquesnel G, Lermuzeaux M, Hazera P, Hanouz JL, Parienti JJ, Du Cheyron D, Demoule A, Clavel M, Rolland-Debord C, Perbet S, Terzi N, Kouatchet A, Wallet F, Roze H, Vargas F, Guérin C, Dellamonica J, Jaber S, Similowski T, Quenot JP, Binquet C, Vinsonneau C, Barbar SD, Vinault S, Deckert V, Lemaire S, Hssain AA, Bruyère R, Souweine B, Lagrost L, Adrie C, Jung B, Daurat A, De Jong A, Chanques G, Mahul M, Monnin M, Molinari N, Lheureux O, Trepo E, Hites M, Cotton F, Wolff F, Surin R, Créteur J, Vincent JL, Gustot T, Jacobs F, Taccone FS, Neuville M, Timsit JF, El-Hel...
Source: Australian Family Physician - May 31, 2016 Category: Primary Care Authors: Jaillette E, Girault C, Brunin G, Zerimech F, Chiche A, Broucqsault-Dedrie C, Fayolle C, Minacori F, Alves I, Barrailler S, Robriquet L, Delaporte E, Thellier D, Delcourte C, Duhamel A, Nseir S, Valette X, Desmeulles I, Savary B, Masson R, Seguin A, Daubi Tags: Ann Intensive Care Source Type: research

'BeAWARE': supporting non-clinical staff within general practice to promptly identify patients presenting with warning signs of heart attack or stroke.
DISCUSSION: BeAWARE fulfils a practice gap in patient safety by improving non-clinical staff's knowledge, confidence and intended action in response to patients presenting with heart attack or stroke warning signs. PMID: 24897991 [PubMed - in process]
Source: Australian Family Physician - June 1, 2014 Category: Primary Care Authors: Poulter C, Stewart M, Fitzpatrick C, Keech W, Stavreski B, Grenfell R Tags: Aust Fam Physician Source Type: research

iPhone ECG screening by practice nurses and receptionists for atrial fibrillation in general practice: the GP-SEARCH qualitative pilot study.
DISCUSSION: AF screening in general practice is feasible. A promising model is likely to be one delivered by a practice nurse, but depends on relevant contextual factors for each practice. PMID: 24791776 [PubMed - in process]
Source: Australian Family Physician - May 1, 2014 Category: Primary Care Authors: Orchard J, Freedman SB, Lowres N, Peiris D, Neubeck L Tags: Aust Fam Physician Source Type: research

Stroke.
Abstract In 2012, about 50 000 Australians had a stroke (cerebrovascular accident (CVA)). The risk of stroke is associated with increased age, previous stroke or transient ischaemic attack, hypertension, smoking, diabetes mellitus (DM), hypercholesterolaemia and atrial fibrillation/flutter (AF). Australian general practice data from the national BEACH program between April 2000 and March 2013 inclusive (1 276 200 GP-patient encounters) were analysed to determine the patient characteristics, associated conditions and management options at those encounters where a CVA was recorded, and detect changes in the annual m...
Source: Australian Family Physician - March 1, 2014 Category: Primary Care Authors: Pollack A, Harrison C, Henderson J, Miller G Tags: Aust Fam Physician Source Type: research