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Prevention of neointimal hyperplasia induced by an endovascular stent via intravenous infusion of mesenchymal stem cells.
CONCLUSIONS: Intravenous infusion of MSCs inhibited the inflammatory reaction to an implanted stent strut, and prevented progressive neointimal hyperplasia in the stented CCA and SCA in a porcine model. Thus, MSC treatment could attenuate the recurrence of cerebral ischemic events after stenting. PMID: 31585431 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - October 3, 2019 Category: Neurosurgery Authors: Nakazaki M, Oka S, Sasaki M, Kataoka-Sasaki Y, Onodera R, Komatsu K, Iihoshi S, Hiroura M, Kawaguchi A, Kocsis JD, Honmou O Tags: J Neurosurg Source Type: research

Effectiveness of staged angioplasty for avoidance of cerebral hyperperfusion syndrome after carotid revascularization.
CONCLUSIONSSAP may be an effective and safe carotid revascularization procedure to avoid CHS. PMID: 30660130 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - January 18, 2019 Category: Neurosurgery Authors: Hayakawa M, Sugiu K, Yoshimura S, Hishikawa T, Yamagami H, Fukuda-Doi M, Sakai N, Iihara K, Ogasawara K, Oishi H, Ito Y, Matsumaru Y Tags: J Neurosurg Source Type: research

Endovascular treatment for emergent large vessel occlusion due to severe intracranial atherosclerotic stenosis.
CONCLUSIONS Both intracranial angioplasty/stenting and intraarterial infusion of a glycoprotein IIb/IIIa inhibitor are effective and safe in the treatment of underlying severe ICAS in acute stroke patients with ELVO. In addition, a lack of a history of stroke/TIA was the only independent predictor of good outcome after endovascular therapy in such patients. PMID: 29932374 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - June 22, 2018 Category: Neurosurgery Authors: Kang DH, Yoon W, Kim SK, Baek BH, Lee YY, Kim YW, Kim YS, Hwang YH, Kim JT, Park MS Tags: J Neurosurg Source Type: research

Submaximal angioplasty for symptomatic intracranial atherosclerosis: a prospective Phase I study.
CONCLUSIONS This study demonstrates the safety of the submaximal angioplasty technique, with no permanent periprocedural complications in 24 treated patients. PMID: 26745485 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - January 8, 2016 Category: Neurosurgery Authors: Dumont TM, Sonig A, Mokin M, Eller JL, Sorkin GC, Snyder KV, Nelson Hopkins L, Levy EI, Siddiqui AH Tags: J Neurosurg Source Type: research

Insufficient platelet inhibition and thromboembolic complications in patients with intracranial aneurysms after stent placement.
CONCLUSIONS The ADP inhibition percentage is related to thromboembolic complications after stent placement for intracranial aneurysms. The increase of the ADP inhibition may decrease the risk of thromboembolic complications. PMID: 26587657 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - November 20, 2015 Category: Neurosurgery Authors: Yang H, Li Y, Jiang Y Tags: J Neurosurg Source Type: research

Vertebral artery transposition for revascularization of the posterior circulation: a critical assessment of temporary and permanent complications and outcomes.
CONCLUSIONS Despite the optimization of medical therapies and lifestyle modifications, a select subset of patients with posterior vascular circulation insufficiency remains. In the authors' experience, vertebral artery-carotid artery transposition provides a surgical option with relatively low long-term complication and restenosis rates that are comparable or lower than those reported with endovascular treatment. PMID: 25397367 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - November 14, 2014 Category: Neurosurgery Authors: Rangel-Castilla L, Kalani MY, Cronk K, Zabramski JM, Russin JJ, Spetzler RF Tags: J Neurosurg Source Type: research

Low-dose intravenous heparin infusion in patients with aneurysmal subarachnoid hemorrhage: a preliminary assessment.
Conclusions In patients with Fisher Grade 3 aSAH whose aneurysm is secured, postprocedure use of a low-dose intravenous heparin infusion may be safe and beneficial. PMID: 24032706 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - September 13, 2013 Category: Neurosurgery Authors: Simard JM, Aldrich EF, Schreibman D, James RF, Polifka A, Beaty N Tags: J Neurosurg Source Type: research