• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Very late ischemic complications in flow-diverter stents: a retrospective analysis of a single-center series.
CONCLUSIONS Very late ischemic complications after FDS treatment were observed in 3.5% of the cases in the authors' series, some of which occurred as late as more than 1 year after placement. PMID: 26824382 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - January 29, 2016 Category: Neurosurgery Authors: Guédon A, Clarençon F, Di Maria F, Rosso C, Biondi A, Gabrieli J, Rojas P, Chiras J, Sourour N Tags: J Neurosurg Source Type: research

Insufficient platelet inhibition and thromboembolic complications in patients with intracranial aneurysms after stent placement.
CONCLUSIONS The ADP inhibition percentage is related to thromboembolic complications after stent placement for intracranial aneurysms. The increase of the ADP inhibition may decrease the risk of thromboembolic complications. PMID: 26587657 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - November 20, 2015 Category: Neurosurgery Authors: Yang H, Li Y, Jiang Y Tags: J Neurosurg Source Type: research

CYP2C19 and CES1 polymorphisms and efficacy of clopidogrel and aspirin dual antiplatelet therapy in patients with symptomatic intracranial atherosclerotic disease.
CONCLUSIONS This is the first study examining genetic variants and their effects in symptomatic ICAD. Variant alleles of CYP2C19 (*2, *3, *8) were associated with lower odds of the primary and secondary composite endpoints. However, the direction of the association was opposite of what is expected based on this SNP. This may reflect an incomplete understanding of this genetic variation and its effect in symptomatic ICAD and warrants further investigations. PMID: 26587656 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - November 20, 2015 Category: Neurosurgery Authors: Hoh BL, Gong Y, McDonough CW, Waters MF, Royster AJ, Sheehan TO, Burkley B, Langaee TY, Mocco J, Zuckerman SL, Mummareddy N, Stephens ML, Ingram C, Shaffer CM, Denny JC, Brilliant MH, Kitchner TE, Linneman JG, Roden DM, Johnson JA Tags: J Neurosurg Source Type: research

Clinical and radiological outcomes following traumatic Grade 3 and 4 vertebral artery injuries: a 10-year retrospective analysis from a Level I trauma center. The Parkland Carotid and Vertebral Artery Injury Survey.
CONCLUSIONS The majority of high-grade blunt VA injuries remain stable or are improved at final follow-up. Despite a 4% rate of radiographic worsening in the Grade 3 blunt VA injury group and a 35% recanalization rate in the Grade 4 blunt VA injury group, there were no adverse clinical outcomes associated with these radiographic changes. No cerebral infarctions were noted in the Grade 3 group. A 7% stroke rate was identified in the Grade 4 blunt VA injury group; however, this was confined to the immediate postinjury period and was associated with 100% mortality. While these data suggest that these high-grade vertebral arte...
Source: Journal of Neurosurgery - October 24, 2014 Category: Neurosurgery Authors: Scott WW, Sharp S, Figueroa SA, Eastman AL, Hatchette CV, Madden CJ, Rickert KL Tags: J Neurosurg Source Type: research

Association between silent embolic cerebral infarction and continuous increase of P2Y12 reaction units after neurovascular stenting.
Conclusions Residual platelet reactivity after dual antiplatelet treatment measured before stenting did not predict poststenting SECI. However, the longer stent and the serial increase of PRU values after stenting were related to SECI. Continuous increase of platelet activation after endovascular procedure may be important in poststent cerebral infarction. PMID: 25036195 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - July 18, 2014 Category: Neurosurgery Authors: Kim BJ, Kwon JY, Jung JM, Lee DH, Kang DW, Kim JS, Kwon SU Tags: J Neurosurg Source Type: research