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Vagus Nerve Stimulation Enhances Stable Plasticity and Generalization of Stroke Recovery Basic Sciences
Conclusions—This study provides the first evidence that VNS paired with rehabilitative training after stroke (1) doubles long-lasting recovery on a complex task involving forelimb supination, (2) doubles recovery on a simple motor task that was not paired with VNS, and (3) enhances structural plasticity in motor networks.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Eric C. Meyers, Bleyda R. Solorzano, Justin James, Patrick D. Ganzer, Elaine S. Lai, Robert L. Rennaker II, Michael P. Kilgard, Seth A. Hays Tags: Animal Models of Human Disease, Rehabilitation, Ischemic Stroke Original Contributions Source Type: research

Safety, Feasibility, and Efficacy of Vagus Nerve Stimulation Paired With Upper-Limb Rehabilitation After Ischemic Stroke Clinical Sciences
Conclusions— This study suggests that VNS paired with rehabilitation is feasible and has not raised safety concerns. Additional studies of VNS in adults with chronic stroke will now be performed. Clinical Trial Registration— URL: https://www.clinicaltrials.gov. Unique identifier: NCT01669161.
Source: Stroke - December 28, 2015 Category: Neurology Authors: Dawson, J., Pierce, D., Dixit, A., Kimberley, T. J., Robertson, M., Tarver, B., Hilmi, O., McLean, J., Forbes, K., Kilgard, M. P., Rennaker, R. L., Cramer, S. C., Walters, M., Engineer, N. Tags: Exercise, Rehabilitation, Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Vagus Nerve Stimulation During Rehabilitative Training Improves Functional Recovery After Intracerebral Hemorrhage Brief Reports
Conclusions— VNS paired with rehabilitative training confers significantly improved forelimb recovery after ICH compared to rehabilitative training without VNS.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Hays, S. A., Khodaparast, N., Hulsey, D. R., Ruiz, A., Sloan, A. M., Rennaker, R. L., Kilgard, M. P. Tags: Animal models of human disease, Exercise/exercise testing/rehabilitation, Other Treatment, Acute Cerebral Hemorrhage, Other Stroke Treatment - Surgical Brief Reports Source Type: research