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Hyperbaric Oxygen Reduces Infarction Volume and Hemorrhagic Transformation Through ATP/NAD+/Sirt1 Pathway in Hyperglycemic Middle Cerebral Artery Occlusion Rats Basic Sciences
Conclusions—HBO induced activation of ATP/nicotinamide adenine dinucleotide/silent mating type information regulation 2 homolog 1 pathway and protected blood–brain barrier in hyperglycemic middle cerebral artery occlusion rats. HBO might be promising approach for treatment of acute ischemic stroke patients, especially patients with diabetes mellitus or treated with r-tPA (recombinant tissue-type plasminogen activator).
Source: Stroke - May 22, 2017 Category: Neurology Authors: Qin Hu, Anatol Manaenko, Hetao Bian, Zongduo Guo, Jun-Long Huang, Zhen-Ni Guo, Peng Yang, Jiping Tang, John H. Zhang Tags: Animal Models of Human Disease, Basic Science Research, Ischemia, Neuroprotectants Original Contributions Source Type: research

Cystatin C Is a Crucial Endogenous Protective Determinant Against Stroke Basic Sciences
Conclusions—CysC is a crucial determinant contributing to endogenous neuroprotection. It is also a novel candidate for stroke treatment through maintaining lysosomal membrane integrity.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Zongping Fang, Jiao Deng, Zhixin Wu, Beibei Dong, Shiquan Wang, Xiaodan Chen, Huang Nie, Hailong Dong, Lize Xiong Tags: Ischemic Stroke, Neuroprotectants Original Contributions Source Type: research

Hyperbaric Oxygen Therapy for Acute Ischemic Stroke Cochrane Corner
Source: Stroke - April 27, 2015 Category: Neurology Authors: Bennett, M. H., Weibel, S., Wasiak, J., Schnabel, A., French, C., Kranke, P. Tags: Acute Cerebral Infarction, Acute Stroke Syndromes, Embolic stroke, Emergency treatment of Stroke, Other Stroke Treatment - Medical Cochrane Corner Source Type: research

Delayed Hyperbaric Oxygen Therapy Promotes Neurogenesis Through Reactive Oxygen Species/Hypoxia-Inducible Factor-1{alpha}/{beta}-Catenin Pathway in Middle Cerebral Artery Occlusion Rats Basic Sciences
Conclusions— Delayed HBO enhanced endogenous neurogenesis and improved neurofunctional recovery in the late-chronic phase of stroke possibly mediated by ROS/HIF-1α/β-catenin pathway. Delayed HBO may serve as an alternative treatment to improve long-term recovery of stroke survivors.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Hu, Q., Liang, X., Chen, D., Chen, Y., Doycheva, D., Tang, J., Tang, J., Zhang, J. H. Tags: Animal models of human disease, Other Stroke Treatment - Medical Basic Sciences Source Type: research