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Source: Stroke
Procedure: Perfusion

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Total 155 results found since Jan 2013.

Perfusion MR Predicts Outcome in High-Risk Transient Ischemic Attack/Minor Stroke: A Derivation-Validation Study Clinical Sciences
Conclusions— Among subjects with high-risk transient ischemic attack and minor stroke, diffusion-weighted imaging–perfusion-weighted imaging mismatch predicts infarct growth and clinical deterioration. These findings suggest that reperfusion strategies would be beneficial in this population.
Source: Stroke - August 26, 2013 Category: Neurology Authors: Asdaghi, N., Hill, M. D., Coulter, J. I., Butcher, K. S., Modi, J., Qazi, A., Goyal, M., Demchuk, A. M., Coutts, S. B. Tags: CT and MRI, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

Arterial Spin-Labeled Perfusion Imaging to Predict Mismatch in Acute Ischemic Stroke Brief Reports
Conclusions— In acute ischemic stroke, PWI lesions based on ASL threshold of <20 mL/100 g per minute can provide a reliable estimate of mismatch in correspondence at MTT threshold of >10 s.
Source: Stroke - August 26, 2013 Category: Neurology Authors: Niibo, T., Ohta, H., Yonenaga, K., Ikushima, I., Miyata, S., Takeshima, H. Tags: Acute Cerebral Infarction Brief Reports Source Type: research

Alberta Stroke Program Early CT Scale Evaluation of Multimodal Computed Tomography in Predicting Clinical Outcomes of Stroke Patients Treated With Aspiration Thrombectomy Clinical Sciences
Conclusions— CT perfusion parameters, evaluated with ASPECTS, are optimal predictors of outcome and are more sensitive and specific than CT ASPECTS in the prediction of favorable outcome. Use of these parameters in treatment decisions could reduce futile recanalizations.
Source: Stroke - July 22, 2013 Category: Neurology Authors: Psychogios, M.-N., Schramm, P., Frolich, A. M., Kallenberg, K., Wasser, K., Reinhardt, L., Kreusch, A. S., Jung, K., Knauth, M. Tags: CT and MRI, Other diagnostic testing, Acute Cerebral Infarction, Emergency treatment of Stroke, Thrombolysis Clinical Sciences Source Type: research

Timing-Invariant Imaging of Collateral Vessels in Acute Ischemic Stroke Clinical Sciences
Conclusions— Collateral vessels may not always be visible on standard single time-frame CTA because of delayed contrast arrival. Future prognostic studies in acute stroke should consider delay-insensitive techniques, such as TI-CTA, instead of standard single time-frame imaging, such as standard CTA.
Source: Stroke - July 22, 2013 Category: Neurology Authors: Smit, E. J., Vonken, E.-j., van Seeters, T., Dankbaar, J. W., van der Schaaf, I. C., Kappelle, L. J., van Ginneken, B., Velthuis, B. K., Prokop, M. Tags: Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Effects of Microvascular Permeability Changes on Contrast-Enhanced T1 and Pharmacokinetic MR Imagings After Ischemia Clinical Sciences
Conclusions— Postischemic brain enhancement on routine CET1-WI seems to be closely related to the luxury reperfusion at the late subacute stage and is not dependent on microvascular permeability changes at the acute stage.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Liu, H.-S., Chung, H.-W., Chou, M.-C., Liou, M., Wang, C.-Y., Kao, H.-W., Chiang, S.-W., Juan, C.-J., Huang, G.-S., Chen, C.-Y. Tags: Acute Cerebral Infarction Clinical Sciences Source Type: research

Clinical Outcomes Strongly Associated With the Degree of Reperfusion Achieved in Target Mismatch Patients: Pooled Data from the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution Studies Clinical Sciences
Conclusion— The degree of reperfusion documented on perfusion-weighted imaging after reperfusion therapies corresponds closely with clinical outcomes in TMM patients. Reperfusion of ≥90% of the perfusion lesion is an appropriate goal for reperfusion therapies to aspire to.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Inoue, M., Mlynash, M., Straka, M., Kemp, S., Jovin, T. G., Tipirneni, A., Hamilton, S. A., Marks, M. P., Bammer, R., Lansberg, M. G., Albers, G. W., for the DEFUSE 1 and 2 Investigators Tags: Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging, Thrombolysis Clinical Sciences Source Type: research

Favorable Vascular Profile is an Independent Predictor of Outcome: A Post Hoc Analysis of the Safety and Efficacy of NeuroFlo Technology in Ischemic Stroke Trial Clinical Sciences
Conclusions— FVP and baseline NIHSS independently predicted outcome in this subset of the SENTIS population. FVP is a novel parameter to predict outcome of acute stroke patients and further studies will establish its potential role for selection of optimal candidates for hemodynamic augmentation. Clinical Trial Registration Information— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00119717
Source: Stroke - May 24, 2013 Category: Neurology Authors: Schellinger, P. D., Kohrmann, M., Liu, S., Dillon, W. P., Nogueira, R. G., Shuaib, A., Liebeskind, D. S., for the SENTIS Trial Investigators Tags: Acute Cerebral Infarction, Emergency treatment of Stroke Clinical Sciences Source Type: research

Autoregulation of Cerebral Blood Flow is Preserved in Primary Intracerebral Hemorrhage Brief Reports
Conclusions— CBF remained stable after acute BP reduction, suggesting some preservation of cerebral autoregulation.
Source: Stroke - May 24, 2013 Category: Neurology Authors: Gould, B., McCourt, R., Asdaghi, N., Dowlatshahi, D., Jeerakathil, T., Kate, M., Coutts, S. B., Hill, M. D., Demchuk, A. M., Shuaib, A., Emery, D., Butcher, K., on behalf of the ICH ADAPT investigators Tags: Acute Cerebral Hemorrhage, Brain Circulation and Metabolism Brief Reports Source Type: research

The Intracerebral Hemorrhage Acutely Decreasing Arterial Pressure Trial Clinical Sciences
Conclusions— Rapid BP lowering after a moderate volume of ICH does not reduce perihematoma CBF. These physiological data indicate that acute BP reduction does not precipitate cerebral ischemia in ICH patients. Clinical Trial Registration Information— URL:http://clinicaltrials.gov. Unique Identifier: NCT00963976.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Butcher, K. S., Jeerakathil, T., Hill, M., Demchuk, A. M., Dowlatshahi, D., Coutts, S. B., Gould, B., McCourt, R., Asdaghi, N., Findlay, J. M., Emery, D., Shuaib, A., for the ICH ADAPT Investigators Tags: Cerebrovascular disease/stroke, Acute Cerebral Hemorrhage, Brain Circulation and Metabolism, Emergency treatment of Stroke, Intracerebral Hemorrhage Clinical Sciences Source Type: research

Periprocedural Arterial Spin Labeling and Dynamic Susceptibility Contrast Perfusion in Detection of Cerebral Blood Flow in Patients With Acute Ischemic Syndrome Clinical Sciences
Conclusions— ASL is less sensitive than DSC for detecting rCBF changes in patients with acute ischemic syndrome, particularly with respect to hyperperfusion after successful recanalization.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Nael, K., Meshksar, A., Liebeskind, D. S., Wang, D. J. J., Ellingson, B. M., Salamon, N., Villablanca, J. P., on behalf of UCLA Stroke investigators Tags: Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging, Other imaging Clinical Sciences Source Type: research

Early Diffusion-Weighted Imaging and Perfusion-Weighted Imaging Lesion Volumes Forecast Final Infarct Size in DEFUSE 2 Clinical Sciences
Conclusions— Baseline DWI and early follow-up PWI (Tmax >6 seconds) volumes provide a reasonable approximation of final infarct volume after endovascular therapy.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Wheeler, H. M., Mlynash, M., Inoue, M., Tipirneni, A., Liggins, J., Zaharchuk, G., Straka, M., Kemp, S., Bammer, R., Lansberg, M. G., Albers, G. W., on behalf of the DEFUSE 2 Investigators Tags: Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Induction of Cooling With a Passive Head and Neck Cooling Device: Effects on Brain Temperature After Stroke Clinical Sciences
Conclusions— Although the decrease of brain temperature after Sovika cooling device application was statistically significant, we doubt clinical relevance of this rather limited effect (–0.36°C). Moreover, the transient increases of blood pressure and ICP warrant caution.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Poli, S., Purrucker, J., Priglinger, M., Diedler, J., Sykora, M., Popp, E., Steiner, T., Veltkamp, R., Bosel, J., Rupp, A., Hacke, W., Hametner, C. Tags: Cerebrovascular disease/stroke, CPR and emergency cardiac care, Other Treatment, Emergency treatment of Stroke Clinical Sciences Source Type: research

Smoking-Thrombolysis Paradox: Recanalization and Reperfusion Rates After Intravenous Tissue Plasminogen Activator in Smokers With Ischemic Stroke Original Contributions
Conclusions— Smoking is independently associated with recanalization and reperfusion, indicating that thrombolytic therapy acts more effectively in smokers; because of small numbers, these results should be considered preliminary. Clinical Trial Registration— URL: http://clinicaltrials.gov. Unique Identifier: NCT00715533.
Source: Stroke - January 18, 2013 Category: Neurology Authors: Kufner, A., Nolte, C. H., Galinovic, I., Brunecker, P., Kufner, G. M., Endres, M., Fiebach, J. B., Ebinger, M. Tags: Fibrinolysis, Angiography, Computerized tomography and Magnetic Resonance Imaging, Risk Factors for Stroke, Thrombolysis Original Contributions Source Type: research

Electrochemical Failure of the Brain Cortex Is More Deleterious When it Is Accompanied by Low Perfusion Basic Sciences
Conclusions— The results suggest that electrochemical failure of the cortex is more deleterious when it is accompanied by low perfusion. Thus, the commitment point of the cortex is not a universal value but depends on additional factors, such as the level of perfusion.
Source: Stroke - January 18, 2013 Category: Neurology Authors: Dreier, J. P., Victorov, I. V., Petzold, G. C., Major, S., Windmuller, O., Fernandez-Klett, F., Kandasamy, M., Dirnagl, U., Priller, J. Tags: Animal models of human disease Basic Sciences Source Type: research

Leukoaraiosis and Sex Predict the Hyperacute Ischemic Core Volume Original Contributions
Conclusions— Severe LA and male sex are associated with larger infarct cores, which adds to the notion that sex and LA alter the brain’s intrinsic susceptibility to acute cerebral ischemia. Future, larger studies are needed to confirm our observation that women have smaller core volumes and its significance.
Source: Stroke - December 24, 2012 Category: Neurology Authors: Henninger, N., Lin, E., Haussen, D. C., Lehman, L. L., Takhtani, D., Selim, M., Moonis, M. Tags: Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging, Risk Factors for Stroke Original Contributions Source Type: research