• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

First Pass Effect Clinical Sciences
Conclusions—The achievement of complete revascularization from a single Solitaire thrombectomy device pass (FPE) is associated with significantly higher rates of good clinical outcome. The FPE is more frequently associated with the use of balloon guide catheters and less likely to be achieved with internal carotid artery terminus occlusion.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Osama O. Zaidat, Alicia C. Castonguay, Italo Linfante, Rishi Gupta, Coleman O. Martin, William E. Holloway, Nils Mueller-Kronast, Joey D. English, Guilherme Dabus, Tim W. Malisch, Franklin A. Marden, Hormozd Bozorgchami, Andrew Xavier, Ansaar T. Rai, Mich Tags: Ischemic Stroke Original Contributions Source Type: research

Comorbid Psychiatric Disease Is Associated With Lower Rates of Thrombolysis in Ischemic Stroke Brief Report
Background and Purpose—Intravenous thrombolysis (IVT) improves outcomes after acute ischemic stroke but is underused in certain patient populations. Mental illness is pervasive in the United States, and patients with comorbid psychiatric disease experience inequities in treatment for a range of conditions. We aimed to determine whether comorbid psychiatric disease is associated with differences in IVT use in acute ischemic stroke.Methods—Acute ischemic stroke admissions between 2007 and 2011 were identified in the Nationwide Inpatient Sample. Psychiatric disease was defined by International Classification of Diseases, ...
Source: Stroke - February 26, 2018 Category: Neurology Authors: Diana M. Bongiorno, Gail L. Daumit, Rebecca F. Gottesman, Roland Faigle Tags: Quality and Outcomes, Ischemic Stroke Brief Reports Source Type: research

Historical Slavery and Modern-Day Stroke Mortality in the United States Stroke Belt Comments and Opinions
Source: Stroke - January 22, 2018 Category: Neurology Authors: Charles Esenwa, Daudet Ilunga Tshiswaka, Mulugeta Gebregziabher, Bruce Ovbiagele Tags: Epidemiology, Race and Ethnicity, Risk Factors, Mortality/Survival, Cerebrovascular Disease/Stroke Comments and Opinions Source Type: research

Arsenic Exposure in Relation to Ischemic Stroke Clinical Sciences
Conclusions—A metabolite of arsenic was positively associated with incident ischemic stroke in this case–cohort study of the US general population, a low-to-moderate exposure area. Overall, these findings suggest a potential role for arsenic methylation in the pathogenesis of stroke, having important implications for future cerebrovascular research.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Cari L. Tsinovoi, Pengcheng Xun, Leslie A. McClure, Vivian M.O. Carioni, John D. Brockman, Jianwen Cai, Eliseo Guallar, Mary Cushman, Frederick W. Unverzagt, Virginia J. Howard, Ka He Tags: Epidemiology, Risk Factors, Ischemic Stroke Original Contributions Source Type: research

Minimal Clinically Important Difference for Safe and Simple Novel Acute Ischemic Stroke Therapies Clinical Sciences
Conclusions—Stroke expert responses to MCID surveys are affected by anchoring and centrality bias. When survey design takes these into account, the expert-derived MCID for a safe acute ischemic stroke treatment is 1.1% to 1.5%, in accord with actual physician behavior in guideline writing and clinical practice. This revised MCID value can guide clinical trial design and grant-funding and regulatory agency decisions.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Jessica S. Cranston, Brett D. Kaplan, Jeffrey L. Saver Tags: Ischemic Stroke, Neuroprotectants Original Contributions Source Type: research

Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke Clinical Sciences
Conclusions—This largest-to-date Solitaire registry documents that the results of the randomized trials can be reproduced in the community. The decrease of clinical benefit over time warrants optimization of the system of care.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT02239640.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Nils H. Mueller-Kronast, Osama O. Zaidat, Michael T. Froehler, Reza Jahan, Mohammad Ali Aziz-Sultan, Richard P. Klucznik, Jeffrey L. Saver, Frank R. Hellinger Jr, Dileep R. Yavagal, Tom L. Yao, David S. Liebeskind, Ashutosh P. Jadhav, Rishi Gupta, Ameer E Tags: Revascularization, Ischemic Stroke Original Contributions Source Type: research

Safety of Simultaneous Coronary Artery Bypass Grafting and Carotid Endarterectomy Versus Isolated Coronary Artery Bypass Grafting Clinical Sciences
Conclusions—Although our results cannot rule out a treatment-group effect because of lack of power, a superiority of the synchronous combined carotid endarterectomy+CABG approach seems unlikely. Five-year follow-up of patients is still ongoing.Clinical Trial Registration—URL: https://www.controlled-trials.com. Unique identifier: ISRCTN13486906.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Christian Weimar, Konstantinos Bilbilis, Jan Rekowski, Torulv Holst, Friedhelm Beyersdorf, Martin Breuer, Manfred Dahm, Anno Diegeler, Arne Kowalski, Sven Martens, Friedrich W. Mohr, Jiri Ondrašek, Beate Reiter, Peter Roth, Ralf Seipelt, Markus Sig Tags: Cardiovascular Surgery Original Contributions Source Type: research

Palliative Care for Hospitalized Patients With Stroke Clinical Sciences
This study explores patterns of palliative care utilization and death in hospitalized patients with stroke across the United States.Methods—Using the 2010 to 2012 nationwide inpatient sample databases, we included all patients discharged with stroke identified by International Classification of Diseases-Ninth Revision codes. Strokes were subclassified as ischemic, intracerebral, and subarachnoid hemorrhage. We compared demographics, comorbidities, procedures, and outcomes between patients with and without a palliative care encounter (PCE) as defined by the International Classification of Diseases-Ninth Revision code V66....
Source: Stroke - August 28, 2017 Category: Neurology Authors: Tarvinder Singh, Steven R. Peters, David L. Tirschwell, Claire J. Creutzfeldt Tags: Race and Ethnicity, Quality and Outcomes, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Coming to the United States for a Stroke Research Fellowship InterSECT
Source: Stroke - July 24, 2017 Category: Neurology Authors: Zixiao Li, Mira Katan Tags: Clinical Studies, Health Services, Cerebrovascular Disease/Stroke InterSECT Source Type: research

Disparities and Trends in Door-to-Needle Time Clinical Sciences
Conclusions—In the FL-PR CReSD, achievement of DTNT ≤60 and DTNT ≤45 remains low. Compared with Whites, Blacks less likely receive tPA treatment within 45 minutes during off hours. Treatment within 60 and 45 minutes is lower in women compared with men and lowest in West Central Florida compared with other Florida regions and Puerto Rico. Further research is needed to identify reasons for delayed thrombolytic treatment in women and Blacks and factors contributing to regional disparities in DTNT.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Sofia A. Oluwole, Kefeng Wang, Chuanhui Dong, Maria A. Ciliberti-Vargas, Carolina M. Gutierrez, Li Yi, Jose G. Romano, Enmanuel Perez, Brittany Ann Tyson, Maranatha Ayodele, Negar Asdaghi, Hannah Gardener, David Z. Rose, Enid J. Garcia, Juan Carlos Zevall Tags: Health Services, Quality and Outcomes, Ischemic Stroke Original Contributions Source Type: research

Training Standards in Neuroendovascular Surgery: Program Accreditation and Practitioner Certification Special Report
Conclusions—Representing neuroendovascular surgery physicians from neurosurgery, neuroradiology, and neurology, the above mentioned societies seek to standardize neuroendovascular surgery training to ensure the highest quality delivery of this subspecialty within the United States.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Arthur L. Day, Adnan H. Siddiqui, Philip M. Meyers, Tudor G. Jovin, Colin P. Derdeyn, Brian L. Hoh, Howard Riina, Italo Linfante, Osama Zaidat, Aquilla Turk, Jay U. Howington, J. Mocco, Andrew J. Ringer, Erol Veznedaroglu, Alexander A. Khalessi, Elad I. L Tags: Statements and Guidelines, Cerebrovascular Disease/Stroke, Vascular Disease Special Reports Source Type: research

How Patient Demographics, Imaging, and Beliefs Influence Tissue-Type Plasminogen Activator Use: A Survey of North American Neurologists Clinical Sciences
Conclusions— Diagnostic certainty and likelihood of treatment with tissue-type plasminogen activator increase with additional clinical data, with the history being the most important factor for diagnostic and treatment decisions. Respondents had difficulty in interpreting the results of CT perfusion scans although they had little impact on treatment decisions. We did not identify treatment bias based on patient age, race, or sex.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Shamy, M. C. F., Pugliese, M., Meisel, K., Rodriguez, R., Kim, A. S., Stahnisch, F. W., Smith, E. E. Tags: Computerized Tomography (CT), Ethics and Policy, Quality and Outcomes, Ischemic Stroke Clinical Sciences Source Type: research

Stroke Legislation Impacts Distribution of Certified Stroke Centers in the United States Clinical Sciences
Conclusions— State stroke legislation, a generalizable intervention, increased the number of certified stroke centers in the United States, potentially improving accessibility of standardized care for patients with acute ischemic stroke.
Source: Stroke - June 22, 2015 Category: Neurology Authors: Uchino, K., Man, S., Schold, J. D., Katzan, I. L. Tags: Health policy and outcome research Clinical Sciences Source Type: research