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Source: Circulation

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Total 925 results found since Jan 2013.

Applying Decision Analysis to Inform the US Food and Drug Administration's Benefit-Risk Assessment of Ticagrelor for Primary Prevention of Myocardial Infarction or Stroke Based on THEMIS
Circulation. 2021 Aug 24;144(8):655-658. doi: 10.1161/CIRCULATIONAHA.120.053294. Epub 2021 Aug 23.NO ABSTRACTPMID:34424771 | DOI:10.1161/CIRCULATIONAHA.120.053294
Source: Circulation - August 23, 2021 Category: Cardiology Authors: Leila G Lackey Christine E Garnett Fred Senatore Source Type: research

Opioid Use and Its Relationship to Cardiovascular Disease and Brain Health: A Presidential Advisory From the American Heart Association
Circulation. 2021 Aug 19:CIR0000000000001007. doi: 10.1161/CIR.0000000000001007. Online ahead of print.ABSTRACTThe misuse of opioids continues to be epidemic, resulting in dependency and a recent upsurge in drug overdoses that have contributed to a significant decrease in life expectancy in the United States. Moreover, recent data suggest that commonly used opioids for the management of pain may produce undesirable pharmacological actions and interfere with critical medications commonly used in cardiovascular disease and stroke; however, the impact on outcomes remains controversial. The American Heart Association developed...
Source: Circulation - August 19, 2021 Category: Cardiology Authors: Sheryl L Chow Comilla Sasson Ivor J Benjamin Robert M Califf Wilson M Compton Elizabeth M Oliva Chester Robson Eduardo J Sanchez American Heart Association Source Type: research

Effect of Rivaroxaban and Aspirin in Patients with Peripheral Artery Disease Undergoing Surgical Revascularization: Insights from the VOYAGER PAD Trial
Conclusions: The efficacy of rivaroxaban is associated with a benefit in surgical LER patients. While bleeding was increased with rivaroxaban plus aspirin, the incidence was low, with no significant increase in fatal bleeding, intracranial hemorrhage or postprocedural bleeds requiring intervention. Clinical Trial Registration: URL: https://clinicaltrials.gov Unique Identifier: NCT02504216.PMID:34380322 | DOI:10.1161/CIRCULATIONAHA.121.054835
Source: Circulation - August 12, 2021 Category: Cardiology Authors: E Sebastian Debus Mark R Nehler Nicholas Govsyeyev Rupert M Bauersachs Sonia S Anand Manesh R Patel Fabrizio Fanelli Warren H Capell Taylor Brackin Franz Hinterreiter Dainis Krievins Patrice Nault Gabriele Piffaretti Alexei Svetlikov Nicole Jaeger Connie Source Type: research

Early Rhythm Control Therapy in Patients with Atrial Fibrillation and Heart Failure
Conclusions: Rhythm control therapy conveys clinical benefit when initiated within one year of diagnosing atrial fibrillation in patients with signs or symptoms of heart failure. Clinical Trial Registration: Unique Identifiers: ISRCTN04708680, NCT01288352, EudraCT2010-021258-20, Study web site www.easttrial.org; URLs: www.controlled-trials.com; https://clinicaltrials.gov; https://www.clinicaltrialsregister.eu.PMID:34328366 | DOI:10.1161/CIRCULATIONAHA.121.056323
Source: Circulation - July 30, 2021 Category: Cardiology Authors: Andreas Rillig Christina Magnussen Ann-Kathrin Ozga Anna Suling Axel Brandes G ünter Breithardt A John Camm Harry J G M Crijns Lars Eckardt Arif Elvan Andreas Goette Michele Gulizia Laurent Haegeli Hein Heidbuchel Karl-Heinz Kuck Andre Ng Lukasz Szumowsk Source Type: research

Lower Extremity Peripheral Artery Disease: Contemporary Epidemiology, Management Gaps, and Future Directions: A Scientific Statement From the American Heart Association
Circulation. 2021 Jul 28:CIR0000000000001005. doi: 10.1161/CIR.0000000000001005. Online ahead of print.ABSTRACTLower extremity peripheral artery disease (PAD) affects >230 million adults worldwide and is associated with increased risk of various adverse clinical outcomes (other cardiovascular diseases such as coronary heart disease and stroke and leg outcomes such as amputation). Despite its prevalence and clinical importance, PAD has been historically underappreciated by health care professionals and patients. This underappreciation seems multifactorial (eg, limited availability of the first-line diagnostic test, the a...
Source: Circulation - July 28, 2021 Category: Cardiology Authors: Michael H Criqui Kunihiro Matsushita Victor Aboyans Connie N Hess Caitlin W Hicks Tak W Kwan Mary M McDermott Sanjay Misra Francisco Ujueta American Heart Association Council on Epidemiology and Prevention; Council on Arteriosclerosis, Thrombosis and Vasc Source Type: research