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Source: Circulation
Nutrition: Maca
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Total 2 results found since Jan 2013.
Cardiovascular Progerin Suppression and lamin A Restoration Rescues Hutchinson-Gilford Progeria Syndrome
Conclusions: HGPSrev mice constitute a new experimental model for advancing knowledge of HGPS. Our findings suggest that it is never too late to treat HGPS, although benefit is much more pronounced when progerin is targeted in mice with mild symptoms. Despite the broad expression pattern of progerin and its deleterious effects in many organs, restricting its suppression to VSMCs and cardiomyocytes is sufficient to prevent vascular disease and normalize lifespan.PMID:34694158 | DOI:10.1161/CIRCULATIONAHA.121.055313
Source: Circulation - October 25, 2021 Category: Cardiology Authors: Amanda S ánchez-López Carla Espin ós-Estévez Cristina Gonz ález-Gómez Pilar Gonzalo Mar ía J Andrés-Manzano V íctor Fanjul Raquel Riquelme-Borja Magda R Hamczyk Álvaro Macías Lara Del Campo Emilio Camafeita Jes ús Vázquez Anna Barkaway Lo ïc Source Type: research
