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Source: Molecular Neurobiology
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Cerebral Ischemic Preconditioning: the Road So Far…
Abstract
Cerebral preconditioning constitutes the brain’s adaptation to lethal ischemia when first exposed to mild doses of a subtoxic stressor. The phenomenon of preconditioning has been largely studied in the heart, and data from in vivo and in vitro models from past 2–3 decades have provided sufficient evidence that similar machinery exists in the brain as well. Since preconditioning results in a transient protective phenotype labeled as ischemic tolerance, it can open many doors in the medical warfare against stroke, a debilitating cerebrovascular disorder that kills or cripples thousands of people worldw...
Source: Molecular Neurobiology - June 17, 2015 Category: Neurology Source Type: research
