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Does renal function have incremental predictive value of stroke in atrial fibrillation?
It is well known that both atrial fibrillation (AF) and chronic kidney disease (CKD) are respectively independent predictors of stroke and systemic thromboembolism. A number of epidemiological and observational studies have shown that there are close relationships between AF and CKD [1 –3]. Indeed, the prevalence of AF increases from non-CKD to CKD stages of 1 to 2, 3 and 4 to 5 by 1.0%, 2.8%, 2.7%, and 4.2%, respectively [1], and the prevalence is 7% to 27% in patients with end-stage renal disease who are undergoing hemodialysis therapy [2].
Source: International Journal of Cardiology - August 28, 2018 Category: Cardiology Authors: Yukihito Higashi Tags: Editorial Source Type: research

Prosthetic valve endocarditis in patients on hemodialysis
We read with great interest the manuscript entitled “Prognostic factors of infective endocarditis in patients on hemodialysis: A case series from a National Multicenter Registry” by Dr. A. Ramos-Martínez and colleagues showing that hemodialysis patients with IE present a high mortality and that advanced age and complications, such as heart failu re, CNS stroke or septic shock, are associated with mortality [1].
Source: International Journal of Cardiology - December 5, 2017 Category: Cardiology Authors: Jinmiao Chen, Kui Hu, Jun Li, Tao Hong, Chunsheng Wang Tags: Correspondence Source Type: research

Atrial Fibrillation and Chronic Kidney Disease Requiring Hemodialysis – Does Warfarin Therapy Improve the Risks of this Lethal Combination?
Warfarin therapy for stroke prevention is recommended for patients with AF, but its value in patients with chronic kidney disease on HD is unknown.
Source: International Journal of Cardiology - July 7, 2016 Category: Cardiology Authors: Lohit Garg, Charity Chen, David E. Haines Source Type: research

Atrial fibrillation and chronic kidney disease requiring hemodialysis — Does warfarin therapy improve the risks of this lethal combination?
Warfarin therapy for stroke prevention is recommended for patients with AF, but its value in patients with chronic kidney disease on HD is unknown.
Source: International Journal of Cardiology - July 7, 2016 Category: Cardiology Authors: Lohit Garg, Charity Chen, David E. Haines Source Type: research

Risk of major cardiovascular events in patients with hemodialysis or peritoneal dialysis with special reference to stroke
Kim et al. determined the incidence rates of major adverse cardiac and cerebrovascular events (MACCE) and compared several types of events between hemodialysis (HD) patients and peritoneal dialysis (PD) patients [1]. The authors handled 22,892 HD patients and 7,387 PD patients in Korea by intention-to-treat method, and median follow-up period was 21.5 months. The risk of several cardiac events in PD patients was significantly higher than that in HD patients. In contrast, the incidence rate of non-fatal hemorrhagic stroke in HD patients showed significantly higher than that in PD patients, and there was no significant diffe...
Source: International Journal of Cardiology - September 21, 2015 Category: Cardiology Authors: Tomoyuki Kawada Source Type: research

The beneficial effects of statins in patients undergoing hemodialysis
Abstract: Background: The beneficial effects of statins in patients undergoing hemodialysis are controversial. Our study aimed to investigate the use of statins and the subsequent risk of cardiovascular morbidity and mortality in patients undergoing hemodialysis.Methods: We conducted a cohort study using data from the Taiwan National Health Insurance Research Database. Cox regressions were performed to determine the hazard ratio (HR) of cardiovascular morbidity and mortality in the HD patients taking statins (statin cohort) compared with a propensity-matched comparison cohort.Results: The statin cohort included a total of ...
Source: International Journal of Cardiology - August 7, 2013 Category: Cardiology Authors: Chin-Chou Huang, Wan-Leong Chan, Yu-Chun Chen, Tzeng-Ji Chen, Chia-Min Chung, Po-Hsun Huang, Shing-Jong Lin, Jaw-Wen Chen, Hsin-Bang Leu Tags: Original Articles Source Type: research

Hemodialysis does not affect ventricular–arterial coupling beyond the reduction of blood pressure and preload
Combined ventricular–arterial coupling defines the efficiency of the myocardium as a pump. The mechanical energy transferred from the ventricular elastance to the arterial elastance is optimal when the two elastances are equal . In hypertension and aging, as well as in patients with renal dysfunction, increased arterial stiffness coupled by a matched increase in ventricular stiffness has been reported . These findings have important hemodynamic consequences, since a stiff heart–arterial system generates more systolic pressure change for a given stroke volume (SV). In particular, patients with end stage renal disease (E...
Source: International Journal of Cardiology - March 1, 2013 Category: Cardiology Authors: Laura Sasso, Alfredo Capuano, Maristella Minco, Antonella Paglia, Flora Pirozzi, Bruno Memoli, Guido Carlomagno, Mario Petretta, Domenico Bonaduce Tags: Letters to the Editor Source Type: research