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Geographic variations in percutaneous versus surgical coronary revascularization: A global perspective from the SYNTAXES trial
The Synergy between PCI with Taxus and Cardiac Surgery (SYNTAX) trial [1] was a landmark trial published by Serruys et al. in 2009 that compared percutaneous coronary intervention (PCI) with first-generation paclitaxel-eluting stents versus coronary artery bypass grafting (CABG) among 1,800 participants with de-novo three-vessel and left main coronary artery disease. The primary endpoint of major adverse cardiac and cerebrovascular events (i.e., death, stroke, myocardial infarction, or repeat revascularization at 12 months) occurred in 17.8% of cases in the PCI group and 12.4% of cases in the CABG group (P=0.002) [1].
Source: International Journal of Cardiology - September 8, 2022 Category: Cardiology Authors: Felice Gragnano, Francesco Pelliccia, Arturo Cesaro, Paolo Calabr ò Tags: Editorial Source Type: research

Looking beyond luminal stenosis in carotid artery disease
I read with interest the comments of Paraskevas and Naylor on the influence of asymptomatic carotid artery stenosis on peri-operative stroke following coronary artery bypass grafting (CABG). The authors have significant expertise in this field and I am in agreement with the views expressed which are in keeping with the findings of our study.
Source: International Journal of Cardiology - April 3, 2018 Category: Cardiology Authors: P. Narayan Tags: Letter to the Editor Source Type: research

Carotid artery stenosis at the time of coronary artery bypass grafting is a risk factor but not a cause for peri-operative stroke
Narayan et al. evaluated whether or not carotid artery screening at the time of coronary artery bypass grafting (CABG) influences neurological outcomes [1]. Two of the four strokes in the group with moderate/severe carotid stenosis occurred on the ipsilateral side of the carotid artery lesion, while two were in areas not related to the side of the carotid artery stenosis. In the group with no significant carotid artery stenosis, 18 patients had a stroke of which 16 were ischemic and 2 were hemorrhagic [1].
Source: International Journal of Cardiology - April 3, 2018 Category: Cardiology Authors: Kosmas I. Paraskevas, A. Ross Naylor Tags: Letter to the Editor Source Type: research

Postoperative ischemic stroke and death prediction with CHA2DS2-VASc score in patients having coronary artery bypass grafting surgery: A nationwide cohort study
This nationwide cohort study was attempted to address the predictive role of CHA2DS2-VASc score in both ischemic stroke and death in patients undergoing coronary artery bypass grafting (CABG) surgery.
Source: International Journal of Cardiology - February 11, 2017 Category: Cardiology Authors: Wei-Syun Hu, Cheng-Li Lin Source Type: research

Risk of stroke with “no-touch” — As compared to conventional off-pump coronary artery bypass grafting. An updated meta-analysis of observational studies
In patients with multivessel coronary disease, compared with percutaneous coronary intervention (PCI) coronary artery bypass grafting (CABG) leads to an unequivocal reduction in long-term mortality, myocardial infarctions and need of repeat revascularization. Previous randomized trial [1] and meta-analysis [2] pointed to that benefit being offset by excess of early and mid-term cerebral strokes after CABG which are associated with increased morbidity and mortality. Alternatively performed off-pump CABG (OPCAB) was shown to reduce some of the complications associated with cardiopulmonary bypass, and in particular cerebrovascular events [3].
Source: International Journal of Cardiology - August 2, 2016 Category: Cardiology Authors: Mariusz Kowalewski, Piotr Suwalski, Wojciech Pawliszak, Federico Benetti, Giuseppe Maria Raffa, Pietro Giorgio Malvindi, Thierry Carrel, Domenico Paparella, Lech Anisimowicz Tags: Correspondence Source Type: research

Coronary surgery is superior to drug eluting stents in multivessel disease. Systematic review and meta-analysis of contemporary randomized controlled trials
Current randomized controlled trials (RCTs) comparing percutaneous coronary intervention with drug eluting stent (DES-PCI) with coronary artery bypass grafting (CABG) in multivessel disease are underpowered to detect a difference in hard clinical end-points such as mortality, myocardial infarction and stroke. We aimed to overcome this limitation by conducting a meta-analysis of contemporary RCTs.
Source: International Journal of Cardiology - February 17, 2016 Category: Cardiology Authors: Umberto Benedetto, Mario Gaudino, Colin Ng, Giuseppe Biondi-Zoccai, Fabrizio D'Ascenzo, Giacomo Frati, Leonard N. Girardi, Gianni D. Angelini, David P. Taggart Source Type: research

Predictive value of the SYNTAX score for short-term cognitive outcomes after off-pump coronary artery bypass surgery
Neuropsychiatric complications of coronary artery bypass grafting (CABG) pose a significant clinical problem that concerns almost one million people undergoing this type of procedure each year worldwide [1]. The severity of these sequelae ranges from minor adverse events (postoperative cognitive decline [POCD], through delirium, depression and psychosis, to major adverse cerebrovascular events (TIA-transient ischemic attack and stroke). There were many efforts to combat this issue, including the development of new surgical techniques (e.g.
Source: International Journal of Cardiology - February 2, 2016 Category: Cardiology Authors: Wojciech Pawliszak, Krzysztof Szwed, Magdalena Szwed, Mariusz Kowalewski, Maciej Bieliński, Małgorzata Piskunowicz, Adam Sukiennik, Katarzyna Zaborowska, Lech Anisimowicz, Alina Borkowska Source Type: research

Comparison of the incidence of postoperative neurologic complications after on-pump versus off-pump coronary artery bypass grafting in high-risk patients: A meta-analysis of 11 studies
Neurological complications, such as stroke and transient ischemic attack, are major adverse cardiac events (MACE) following coronary artery bypass grafting (CABG) and markedly reduce patient short-term and long-term survival [1]. Farkouh et al. found that the 5-year rate of stroke was significantly higher after CABG than after percutaneous coronary intervention in patients with diabetes and multivessel coronary artery disease [2]. Thus, strategies to reduce neurological complications after CABG can improve patient outcomes.
Source: International Journal of Cardiology - March 11, 2015 Category: Cardiology Authors: Jiayang Wang, Chengxiong Gu, Mingxin Gao, Wenyuan Yu, Haitao Li, Fan Zhang, Yang Yu Tags: Letters to the Editor Source Type: research

Patient and physician perspectives on outcomes weighting in revascularization. The POWR study
Half a million Americans undergo coronary artery bypass grafting (CABG) and about one million undergo percutaneous coronary interventions (PCI) every year 1. The high volume of revascularization procedures has led to several outcome comparisons between PCI and CABG. While the comparison variables for each trial are different, the outcomes are usually predefined to be end points such as death, stroke, myocardial infarction, and repeat revascularization grouped into a category labeled major adverse cardiovascular events (MACE).
Source: International Journal of Cardiology - August 23, 2014 Category: Cardiology Authors: Jay Pandit, Vipul Gupta, Nathan Boyer, Yerem Yeghiazarians, Thomas A. Ports, Andrew J. Boyle Tags: Letter to the Editor Source Type: research

Patient and Physician Perspectives on Outcomes Weighting in Revascularization. The POWR Study
Half a million Americans undergo coronary artery bypass grafting (CABG) and about one million undergo percutaneous coronary interventions (PCI) every year1. The high volume of revascularization procedures has led to several outcome comparisons between PCI and CABG. While the comparison variables for each trial are different, the outcomes are usually predefined to be end points such as death, stroke, myocardial infarction, repeat revascularization etc. grouped into a category labeled major adverse cardiovascular events (MACE).
Source: International Journal of Cardiology - August 23, 2014 Category: Cardiology Authors: Jay Pandit, Vipul Gupta, Nathan Boyer, Yerem Yeghiazarians, Thomas A. Ports, Andrew J. Boyle Source Type: research

Angiographic success and procedural complications in patients undergoing retrograde percutaneous coronary chronic total occlusion interventions: A weighted meta-analysis of 3482 patients from 26 studies
Conclusions: Retrograde CTO PCI is associated with high procedural success rate and acceptable risk for procedural complications.
Source: International Journal of Cardiology - April 25, 2014 Category: Cardiology Authors: Abdallah El Sabbagh, Vishal G. Patel, Omar M. Jeroudi, Tesfaldet T. Michael, Mohammed E. Alomar, Owen Mogabgab, Eric Fuh, Michele Roesle, Bavana V. Rangan, Shuaib Abdullah, Jeffrey L. Hastings, Jerrold Grodin, Dharam J. Kumbhani, Dimitrios Alexopoulos, Pa Tags: Reviews Source Type: research

CABG versus PCI in diabetic patients with multivessel disease after risk stratification by the SYNTAX score: A pooled analysis of the SYNTAX and FREEDOM trials
The 2010 European guidelines for myocardial revascularization indicate coronary artery bypass grafting (CABG) as a class I recommendation for patients with stable coronary multivessel disease (MVD), regardless of the angiographic burden reflected by the SYNTAX score . In contrast, percutaneous coronary intervention (PCI) is contraindicated (class III) in patients with MVD and intermediate to high (>22) SYNTAX score, while it is considered reasonable (class IIa) in patients with MVD and low (0–22) SYNTAX score. Recently, in the 2013 European guidelines on the management of patients with diabetes mellitus, PCI for MVD has ...
Source: International Journal of Cardiology - April 3, 2014 Category: Cardiology Authors: Davide Capodanno, Piera Capranzano, Corrado Tamburino Tags: Letters to the Editor Source Type: research

Acute kidney injury and long-term risk of stroke after coronary artery bypass surgery
This study investigated the association between AKI and long-term risk of stroke.Methods and results: 50,244 patients who underwent coronary artery bypass grafting (CABG) in Sweden between 2000 and 2008 were identified from the SWEDEHEART registry. After exclusions 23,584 patients without prior stroke who underwent elective, primary, isolated, CABG were included. AKI was categorized according to absolute increases in postoperative creatinine values compared with preoperative values: stage 1, 0.3–0.5mg/dL (26–44μmol/L); stage 2, 0.5–1.0mg/dL (44–88μmol/L); and stage 3,>1.0mg/dL (≥88μmol/L). Cox proportional haz...
Source: International Journal of Cardiology - September 9, 2013 Category: Cardiology Authors: Martin J. Holzmann, Linda Rydén, Ulrik Sartipy Tags: Original Articles Source Type: research

Meta-analysis of stroke after transradial versus transfemoral artery catheterization
Conclusions: TR catheterization is not associated with a significant increase in stroke compared to TF catheterization.
Source: International Journal of Cardiology - August 30, 2013 Category: Cardiology Authors: Vishal G. Patel, Kimberly M. Brayton, Dharam J. Kumbhani, Subhash Banerjee, Emmanouil S. Brilakis Tags: Original Articles Source Type: research

Coronary artery bypass grafting in patients with left ventricular dysfunction: Predictors of long-term survival and impact of surgical strategies
This study aimed to determine predictors of clinical outcomes in patients with severe LV dysfunction undergoing CABG.Methods: Out of 6084 patients who underwent CABG between 1997 and 2011, 476 patients (aged 62.6±9.3years, 100 females) were identified as having severe LV dysfunction (ejection fraction≤35%), preoperatively. All-cause mortality and adverse cardiac events (myocardial infarction, repeat revascularization, stroke and hospitalization due to cardiovascular causes) were evaluated during a median follow-up period of 55.2months (inter-quartile range: 26.4–94.8months).Results: During the follow-up, 187 patients ...
Source: International Journal of Cardiology - August 26, 2013 Category: Cardiology Authors: Jae Suk Yoo, Joon Bum Kim, Sung-Ho Jung, Suk Jung Choo, Cheol Hyun Chung, Jae Won Lee Tags: Original Articles Source Type: research

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