• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Morbid Obesity is Associated with Increased Procedural Complications and Worse In-Hospital Outcomes after Percutaneous Left Atrial Appendage Occlusion Device Implantation
Obesity has adverse effects on cardiovascular hemodynamics and is an independent risk factor for the induction and perpetuation of atrial fibrillation (AF) (1). Percutaneous left atrial appendage occlusion (LAAO) has shown promising results in reducing stroke risk in select AF patients who cannot be managed with a conventional long-term oral anticoagulation strategy (2). In the landmark PROTECT-AF trial evaluating the efficacy and safety of percutaneous LAAO, patients receiving LAAO device had a mean BMI of 31.6 kg/m2 (2), however, no distinct assessment of outcomes were conducted based on body weight.
Source: Heart Rhythm - December 26, 2022 Category: Cardiology Authors: Siddharth Agarwal, Zain Ul Abideen Asad, Muhammad Zia Khan, Lydia Fekadu Messele, Douglas Darden, Deepak Kumar Pasupula, Gagan D. Singh, Uma N. Srivatsa, Salman Zahid, Sudarshan Balla, Christopher V. DeSimone, Abhishek Deshmukh, Muhammad Bilal Munir Source Type: research

Po-614-05 a community hospital review of watchman outcomes to determine safe discharge protocols
Left atrial appendage occlusion (LAAO) devices are increasingly used to decrease the risk of stroke in atrial fibrillation patients with contraindication to oral anticoagulation. Discharge protocols after this procedure are variable, and same day discharge (SDD) may improve inpatient bed utilization.
Source: Heart Rhythm - April 29, 2022 Category: Cardiology Authors: Jill Boone Schaeffer, Diane N. Bollinger Source Type: research

Po-641-05 safety and in-hospital outcomes of left atrial appendage closure device in patients with heart failure: an analysis from the national inpatient sample database 2015-2018
Left atrial appendage occlusion (LAAO) is a procedure that has been shown to be non-inferior to oral anticoagulation for stroke prevention for patients with atrial fibrillation. There is limited data about the safety of left atrial appendage occlusion (LAAO) in patients with heart failure (HF).
Source: Heart Rhythm - April 29, 2022 Category: Cardiology Authors: Carlos Vergara Sanchez, Michael Dangl, Michael Albosta, Ian Ergui, Karla Inestroza, Jennifer Maning, Louis Thomas Vincent, Jelani K. Grant, Bertrand Ebner, Rosario Colombo Source Type: research

Po-661-07 a photoplethymography-based approach to atrial fibrillation-burden estimation in high-risk patients
Atrial fibrillation (AF) is the most common arrhythmia leading to hospital admission. Its incidence is linked to increased risk of stroke, congestive heart failure, and overall mortality. AF burden is a key determinant of outcomes, but accurate quantification can be limited by the cardiac monitoring period (typically days). Alternatively, longer-term monitoring comes at higher cost and often requires an invasive approach. The introduction of reliable wrist-worn devices may improve access to long-term monitoring of AF burden.
Source: Heart Rhythm - April 29, 2022 Category: Cardiology Authors: Charles A. Athill, Yuriko Tamura, Steven Szabados, Anthony Battisti, Jeffrey Ellis, Lori Crosson, Judith C. Lenane Source Type: research

Liver cirrhosis is independently associated with increased in-hospital mortality in patients undergoing left atrial appendage occlusion device implantation
This study aimed to assess procedural outcomes in patients with cirrhosis who underwent LAAO with a Watchman device by using a contemporary administrative claims database.
Source: Heart Rhythm - April 28, 2022 Category: Cardiology Authors: Sahith Reddy Thotamgari, Aakash R. Sheth, Harsh P. Patel, John Bretzman, Robert C. Ward, Samarthkumar Thakkar, Jaimin T. Patel, Samuel J. Asirvatham, David R. Holmes, Alexander Egbe, Abhishek Deshmukh, Christopher V. DeSimone Tags: Research Letter Source Type: research

The impact of heart rate circadian rhythm on in-hospital mortality in stroke and critically ill patients: insights from the eICU Collaborative Research Database
Data showing the impact of dysregulated heart rate circadian rhythm in stroke and critically ill patients are scarce.
Source: Heart Rhythm - March 30, 2022 Category: Cardiology Authors: Zhengning Yang, Zhe Li, Xu He, Zhen Yao, Xiaoxia Xie, Sha Zhang, Yan Shen, Shaowei Li, Shuzhen Qiao, Zhenliang Hui, Chao Gao, Jun Chen Source Type: research

The impact of heart rate circadian rhythm on in-hospital mortality in patients with stroke and critically ill: Insights from the eICU Collaborative Research Database
Data showing the impact of dysregulated heart rate circadian rhythm in patients with stroke and critically ill are scarce.
Source: Heart Rhythm - March 30, 2022 Category: Cardiology Authors: Zhengning Yang, Zhe Li, Xu He, Zhen Yao, Xiaoxia Xie, Sha Zhang, Yan Shen, Shaowei Li, Shuzhen Qiao, Zhenliang Hui, Chao Gao, Jun Chen Source Type: research

B-po03-156 procedural complications and in-hospital outcomes from left atrial appendage occlusion device implantation in patients with chronic and end stage renal disease
The Watchman device has emerged as an alternative strategy to oral anticoagulation for mitigating ischemic stroke risk in selected patients with atrial fibrillation (AF), but safety data in patients with kidney disease are limited.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Muhammad Bilal Munir, Muhammad Zia Khan, Douglas Darden, Deepak Kumar Pasupula, Sudarshan Balla, Frederick T. Han, Ryan Reeves, Jonathan C. Hsu Source Type: research

Pericardial Effusion Requiring Intervention in Patients Undergoing Percutaneous Left Atrial Appendage Occlusion: Prevalence, Predictors and Associated In-hospital Adverse Events from 17,700 Procedures in the United States
Left atrial appendage occlusion has shown promise in mitigating risk of stroke in selected patients with atrial fibrillation.
Source: Heart Rhythm - May 17, 2021 Category: Cardiology Authors: Muhammad Bilal Munir, Muhammad Zia Khan, Douglas Darden, Deepak Kumar Pasupula, Sudarshan Balla, Frederick T. Han, Ryan Reeves, Jonathan C. Hsu Source Type: research

EP News Clinical October 2020
Kirchhof and colleagues et al. (N Engl J Med. 2020;383(14):1305-1316 PMID: 32865375) randomized patients with early atrial fibrillation (AF) to rhythm control or usual care. The first primary outcome was a composite of cardiovascular death, stroke, or hospitalization with heart failure heart failure or coronary syndrome. The second primary outcome was the number of nights spent in the hospital. The trial was stopped for efficacy after a median of 5.1 years of follow-up of 2789 patients. A first-primary-outcome event occurred in 249 patients with rhythm control (3.9/100 person-years) and in 316 patients with usual care (5.0...
Source: Heart Rhythm - October 10, 2020 Category: Cardiology Authors: N A Mark Estes Source Type: research

EP News: Clinical
Kirchhof et  al (N Engl J Med 2020;383:1305, PMID 32865375) randomized patients with early atrial fibrillation (AF) to rhythm control or usual care. The first primary outcome was a composite of cardiovascular death, stroke, or hospitalization with heart failure or coronary syndrome. The second primary outcome was the number of nights spent in the hospital. The trial was stopped for efficacy after a median of 5.1 years of follow-up of 2789 patients. A first primary outcome event occurred in 249 patients with rhythm control (3.9/100 person-years) and in 316 patients with usual care (5.0/100 person-years) ( P = .005).
Source: Heart Rhythm - October 10, 2020 Category: Cardiology Authors: N.A. Mark Estes Tags: EP News Source Type: research

Impact of atrial fibrillation/flutter on the in-hospital mortality of ischemic stroke patients
Stroke is the second leading cause of death worldwide. Ischemic strokes, which are caused by atrial fibrillation/flutter (AF) may be more devastating than those without AF.
Source: Heart Rhythm - October 3, 2019 Category: Cardiology Authors: Karsten Keller, Lukas Hobohm, Philip Wenzel, Thomas M ünzel, Christine Espinola-Klein, Mir A. Ostad Source Type: research

Incidence and Causes of In-hospital Outcomes and 30-day Readmissions After Percutaneous Left Atrial Appendage Closure: A United States Nationwide Retrospective Cohort Study Using Claims Data
Percutaneous left atrial appendage closure (p-LAAC) emerged as an option for stroke prevention in atrial fibrillation (AF) patients ’ ineligible for long-term anticoagulation.Real-world data on its in-hospital and 30-day readmission measures are limited.
Source: Heart Rhythm - September 16, 2019 Category: Cardiology Authors: Venkat L.K. Vuddanda, Mohit K. Turagam, Nikita A. Umale, Zubair Shah, Dhanunjaya R. Lakkireddy, Krzysztof Bartus, Finnian R. McCausland, Poonam Velagapudi, Moussa Mansour, E. Kevin Heist Source Type: research

Right superior vena cava drainage into the left atrium revealed by multiples strokes after pacemaker implantation
An 84-year-old woman had undergone dual-chamber pacemaker implantation in a primary care hospital for sick sinus syndrome. The leads were inserted through the right subclavian vein because the patient was left-handed. One year later, she suffered from an ischemic stroke. During ventricular pacing, ECG showed a right bundle branch block pattern, and chest radiography (A) suggested that pacing lead tips were in the left atrium (LA) and left ventricle. After transthoracic and transesophageal echocardiography, it was initially thought that the leads passed through a patent foramen ovale. A thrombus on the ventricular lead was ...
Source: Heart Rhythm - August 2, 2012 Category: Cardiology Authors: Pierre-Yves Courand, Nicolas Girerd, Samuel Chauveau, Philippe Chevalier Tags: Images Source Type: research