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Po-716-07 is cha2ds2vasc score useful for predicting the risk of stroke in patients with atrial fibrillation and cancer? : a single-center observational analysis
Patients with active cancer were historically excluded from clinical trials validating the CHA2DS2VASc score for stroke prediction in atrial fibrillation (AF). Limited data have questioned the predictive value of the score in patients with cancer and AF, underscoring the need for more personalized scores for prediction of stroke in these patients.
Source: Heart Rhythm - April 29, 2022 Category: Cardiology Authors: Udhayvir S. Grewal, Mohammad Bhuiyan, Nachiket Madhav APTE, Parinita A. Dherange, Paari Dominic Source Type: research

Strategies to balance stroke and bleeding risk in patients with atrial fibrillation and cancer
A 76-year-old female with obesity, hypertension, persistent atrial fibrillation, and heart failure with preserved ejection fraction is started on ibrutinib 420 mg once daily for Waldenstrom ’s macroglobulinemia. Due to concern for drug-drug interactions, her amiodarone is decreased from 200 to 100 mg daily, and she is continued on metoprolol succinate 100 mg daily and apixaban 5 mg twice daily. She presents to the clinic one month later with extensive superficial ecchymoses, and her apixaban dose is reduced to 2.5 mg twice daily due to concerns that this may reflect the combined antiplatelet effects of ibrutinib and anti...
Source: Heart Rhythm - April 27, 2021 Category: Cardiology Authors: Shiv Bagga, Sourbha S. Dani, Bruce G. Hook, Anju Nohria, Sarju Ganatra Source Type: research