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Double the Trouble: Acute Coronary Syndrome and Ischemic Stroke in Polycythemia Vera
Vague symptoms turned out to be life-threatening conditions. A 50 year-old man with a history of polycythemia vera, presented to hospital with epigastric discomfort and clumsiness of the right hand for 5 days. Polycythemia vera was diagnosed 1 year prior with good control of hematocrit by intermittent phlebotomy. He did not have any other medical history, and was not taking any medications. He denied chest pain, shortness of breath, nausea, headache, vision change, or speech difficulty.
Source: The American Journal of Medicine - March 12, 2017 Category: Journals (General) Authors: Hitomi Hosoya, Jeffrey J. Levine, David H. Henry, Sheldon Goldberg Tags: Diagnostic Dilemma Source Type: research

Venous and Arterial Viscosity-associated Thrombosis in Hemoglobin SC Disease
I read with interest the article of Naik et al highlighting the risk of venous thrombosis in patients suffering from sickle cell disease. However, the authors may have missed the opportunity to address an important issue by studying separately sickle cell anemia and hemoglobin SC patients whose clinical presentation, pathogenesis, treatment and evolution are quite different. Hemoglobin SC patients usually are not anemic or only mildly anemic, and hyperviscosity plays a key role in the pathogenesis of complications observed in this disease. We showed in a recent study that life-threatening complication observed in hemoglo...
Source: The American Journal of Medicine - September 25, 2013 Category: Journals (General) Authors: François Lionnet Tags: Letters Source Type: research