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Source: The American Journal of Medicine

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Total 259 results found since Jan 2013.

Prevalence and significance of unrecognized renal dysfunction in patients with stroke
Unrecognized renal dysfunction, defined as estimated glomerular filtration rate
Source: The American Journal of Medicine - May 19, 2016 Category: Journals (General) Authors: David Pereg, Zach Rozenbaum, Dina Vorobeichik, Nir Shlomo, Ronit Gilad, Sivan Bloch, Morris Mosseri, David Tanne Tags: Clinical Research Study Source Type: research

Unmasking a Hidden Cause of Persistent Facial Ulceration The Relevancy of a Neurologic Examination
A 49-year-old woman presented to the emergency room of a tertiary medical center for evaluation of chronic facial ulceration. Her past medical history was significant for type II diabetes mellitus, hypothyroidism, antiphospholipid antibody syndrome, venous thromboembolism, and stroke. The patient noted progressive ulceration around the left nasal ala with extension to the left eyebrow and eyelid for 2 years. She had been evaluated for this problem numerous times at outside medical facilities. Previous treatments included three 6-week courses of intravenous vancomycin, one 6-week course of daptomycin, and one 2-week course of oral acyclovir.
Source: The American Journal of Medicine - May 19, 2016 Category: Journals (General) Authors: Kyle W. Mahoney, Jules B. Lipoff, Bennett W. Clark Tags: Diagnostic Dilemma Source Type: research

The Call for a Physical Activity Vital Sign in Clinical Practice
According to the Bureau of Labor Statistics, the most common shared occupational health risk is sedentary behavior. Physical inactivity increases the relative risk of coronary artery disease, stroke, hypertension and osteoporosis by 45%, 60%, 30%, and 59% respectively.1 Epidemiologic data suggest that physical inactivity is associated with an increased risk of 25 chronic diseases.2 Due to the fact that approximately 90% of American adults do not meet current physical activity guidelines,5 deaths attributable to physical inactivity may soon exceed those attributed to cigarette smoking,3,4 For these reasons, physical inactiv...
Source: The American Journal of Medicine - May 23, 2016 Category: Journals (General) Authors: Robert E. Sallis, Aaron L. Baggish, Barry A. Franklin, James R. Whitehead Tags: Commentary Source Type: research

Unmasking a Hidden Cause of Persistent Facial Ulceration: The Relevancy of a Neurologic Examination
A 49-year-old woman presented to the Emergency Department of a tertiary medical center for evaluation of chronic facial ulceration. Her past medical history was significant for type II diabetes mellitus, hypothyroidism, antiphospholipid antibody syndrome, venous thromboembolism, and stroke. The patient noted progressive ulceration around the left nasal ala with extension to the left eyebrow and eyelid for 2 years. She had been evaluated for this problem numerous times at outside medical facilities.
Source: The American Journal of Medicine - May 19, 2016 Category: Journals (General) Authors: Kyle W. Mahoney, Jules B. Lipoff, Bennett W. Clark Tags: Diagnostic dilemma Source Type: research

The limited public health impact of “lifestyle” change
Two main factors are responsible for premature disease and mortality. One is smoking, often referred to as a “lifestyle choice”, but better described as a “habit”. The other is poor nutrition resulting largely from the sugar, alcohol, salt, and saturated fat content (SASS components) of ready to consume food and drink, much of which is manufactured on an industrial scale. Collectively these dietary components are the main drivers of the global epidemic of stroke, heart attack, obesity, and type 2 diabetes.
Source: The American Journal of Medicine - July 14, 2016 Category: Journals (General) Authors: Nicholas J. Wald Tags: Editorial Source Type: research

From Leptin, DEXA, and Beyond
Kahn and Bullard “recommend that waist circumference be added to BMI [body mass index] as a primary tool for assessing adiposity.”1 Suggesting “a need for alternative approaches to anthropometry”1 is necessary because BMI incorrectly classifies obesity by 39%.2 Many adults are obese by American Society of Ba riatric Physicians criteria of body fat: ≥25% for men and ≥30% for women.3 Normal-weight obese adults have increased mortality risk from diabetes, hypertension, heart disease, stroke, cancer, dyslipidemia, liver and gallbladder disease, sleep apnea and respiratory problems, and osteoarthritis.
Source: The American Journal of Medicine - July 22, 2016 Category: Journals (General) Authors: Eric R. Braverman Tags: AJM online Source Type: research

The limited public health impact of “lifestyle” change
Two main factors are responsible for premature disease and mortality. One is smoking, often referred to as a “lifestyle choice”, but better described as a “habit”. The other is poor nutrition resulting largely from the sugar, alcohol, salt, and saturated fat content (SASS components) of ready to consume food and drink, much of which is manufactured on an industrial scale. Collectively these dietary components are the main drivers of the global epidemic of stroke, heart attack, obesity, and type 2 diabetes.
Source: The American Journal of Medicine - July 14, 2016 Category: Journals (General) Authors: Nicholas J. Wald Tags: Editorial Source Type: research

The Call for a Physical Activity Vital Sign in Clinical Practice
According to the Bureau of Labor Statistics, the most common shared occupational health risk is sedentary behavior. Physical inactivity increases the relative risk of coronary artery disease, stroke, hypertension, and osteoporosis by 45%, 60%, 30%, and 59%, respectively.1 Epidemiologic data suggest that physical inactivity is associated with an increased risk of 25 chronic diseases.2 Because approximately 90% of American adults do not meet current physical activity guidelines,3 deaths attributable to physical inactivity may soon exceed those attributed to cigarette smoking.
Source: The American Journal of Medicine - May 23, 2016 Category: Journals (General) Authors: Robert E. Sallis, Aaron L. Baggish, Barry A. Franklin, James R. Whitehead Tags: Commentary Source Type: research

Unmasking a Hidden Cause of Persistent Facial Ulceration: The Relevancy of a Neurologic Examination
A 49-year-old woman presented to the Emergency Department of a tertiary medical center for evaluation of chronic facial ulceration. Her past medical history was significant for type II diabetes mellitus, hypothyroidism, antiphospholipid antibody syndrome, venous thromboembolism, and stroke. The patient noted progressive ulceration around the left nasal ala with extension to the left eyebrow and eyelid for 2 years. She had been evaluated for this problem numerous times at outside medical facilities.
Source: The American Journal of Medicine - May 19, 2016 Category: Journals (General) Authors: Kyle W. Mahoney, Jules B. Lipoff, Bennett W. Clark Tags: Diagnostic dilemma Source Type: research

Sudden Cardiac Arrest From Heat Stroke: Hidden Dangers of Hot Yoga
A healthy 35-year-old woman, 12 weeks postpartum, was in her hot yoga class when she suddenly became unresponsive. Cardiopulmonary resuscitation (CPR) was started on the patient promptly. Emergency Medical Services arrived 5 minutes into initiation of CPR. Examination revealed warm skin, dilated pupils, and frank blood foaming from her mouth. Rhythm was consistent with ventricular fibrillation. Forty-five minutes of CPR was performed prior to return of spontaneous circulation, after which the patient was placed on vasopressor support.
Source: The American Journal of Medicine - April 19, 2016 Category: Journals (General) Authors: Prajwal Boddu, Suhag Patel, Anahita Shahrrava Tags: AJM online Source Type: research

Major Outcomes in Atrial Fibrillation Patients with One Risk Factor: Impact of Time in Therapeutic Range Observations from the SPORTIF Trials
The benefits and harms of oral anticoagulation therapy in patients with only one stroke risk factor (ie, CHA2DS2-VASc  = 1 in males, or 2 in females) has been a subject of debate.
Source: The American Journal of Medicine - April 14, 2016 Category: Journals (General) Authors: Marco Proietti, Gregory Y.H. Lip Tags: Clinical research study Source Type: research

Usefulness of CHADS2 and CHA2DS2-VASc Scores in the Prediction of New-Onset Atrial Fibrillation: A Population-Based Study
CHADS2 and CHA2DS2-VASc are validated scores used to predict stroke in patients with atrial fibrillation. Many of the individual risk factors included in these scores are also risk factors for atrial fibrillation. We aimed to examine the performance of CHADS2 and CHA2DS2-VASc scores in predicting new-onset atrial fibrillation in subjects without preexisting diagnosis of atrial fibrillation.
Source: The American Journal of Medicine - March 20, 2016 Category: Journals (General) Authors: Walid Saliba, Naomi Gronich, Ofra Barnett-Griness, Gad Rennert Tags: Clinical research study Source Type: research

Migrating Susceptibility Vessel Sign in Posterior Circulation Stroke
A 95-year-old woman with atrial fibrillation was admitted with acute onset of disturbed consciousness. On admission, neurological deficits rapidly improved and completely disappeared. The prothrombin time –international normalized ratio was 1.4 although she was medicated with warfarin (2.5 mg/day). Brain magnetic resonance (MR) imaging with diffusion-weighted imaging (DWI) findings on admission were normal, but MR angiography (MRA) detected basilar-top occlusion, and susceptibility-weighted imaging (SWI) confirmed the susceptibility vessel sign at the basilar top (Figure, A and E).
Source: The American Journal of Medicine - March 10, 2016 Category: Journals (General) Authors: Teppei Komatsu, Hidetaka Mitsumura, Satoshi Matsushima, Yasuyuki Iguchi Tags: AJM online Source Type: research

From Leptin, DEXA, and Beyond
Kahn and Bullard “recommend that waist circumference be added to BMI [body mass index] as a primary tool for assessing adiposity.”1 Suggesting “a need for alternative approaches to anthropometry”1 is necessary because BMI incorrectly classifies obesity by 39%.2 Many adults are obese by American Society of Ba riatric Physicians criteria of body fat: ≥25% for men and ≥30% for women.3 Normal-weight obese adults have increased mortality risk from diabetes, hypertension, heart disease, stroke, cancer, dyslipidemia, liver and gallbladder disease, sleep apnea and respiratory problems, and osteoarthritis.
Source: The American Journal of Medicine - July 28, 2016 Category: Journals (General) Authors: Eric R. Braverman Tags: AJM online Source Type: research

The Reply
The authors thank Xue et al for their interest in our article titled “Association between Anemia, Bleeding, and Transfusion with Long-Term Mortality Following Non-Cardiac Surgery.”1 We share the authors' concern about the potential for residual confounding in this observational analysis of a large single-center surgical database. The initial analysis adjusted for age, sex, race, elective vs emergency/urgent surgery, procedure type, and the individual components of the Revised Cardiac Risk Index including coronary artery disease, heart failure, stroke/transient ischemic attack, creatinine>2 mg/dL, and diabetes mellitus.
Source: The American Journal of Medicine - August 21, 2016 Category: Journals (General) Authors: Nathaniel R. Smilowitz, Jeffrey S. Berger Tags: AJM online Source Type: research