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Source: The American Journal of Medicine
Condition: Ischemic Stroke
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Total 59 results found since Jan 2013.
Erratum to ‘Blood Pressure Trajectories and Outcomes for Veterans Presenting at VA Medical Centers with a Stroke or Transient Ischemic Attack’ The American Journal of Medicine (2022) Volume 135, Issue 7, 889-896.e1
The publisher regrets that the following affiliations were incorrect at the time the article was published; however these have now been corrected.
Source: The American Journal of Medicine - November 22, 2022 Category: General Medicine Authors: Greg Arling, Anthony Perkins, Laura J. Myers, Jason J. Sico, Dawn M. Bravata Tags: Erratum Source Type: research
Inflammatory bowel disease and cardiovascular diseases
Inflammatory Bowel Disease is comprised of two major subtypes: Crohn's disease and ulcerative colitis, characterized by chronic inflammation of the gastrointestinal tract with extraintestinal manifestations that can involve a number of systems.1 There were estimated to be 7 million cases of inflammatory bowel disease globally in 2017, and at the national level, the United States had the highest age-standardized prevalence rate (464.5 per 100,000 population) of inflammatory bowel disease.2 Atherosclerotic cardiovascular diseases is defined as a history of acute coronary syndrome, myocardial infarction, stable or unstable an...
Source: The American Journal of Medicine - September 1, 2022 Category: General Medicine Authors: Bing Chen, Lauren V Collen, Craig Mowat, Kim L. Isaacs, Siddharth Singh, Sunanda V. Kane, Edward V. Loftus, Francis A. Farraye, Scott Snapper, Hani Jneid, Carl J Lavie, Chayakrit Krittanawong Tags: Clinical Research Study Source Type: research
Quality of Care Among Patients with Diabetes and Cerebrovascular Disease. Insights from The Diabetes Collaborative Registry
Not only do patients with type 2 diabetes have increased risks of coronary artery disease and peripheral artery disease, but they also have least a two-fold increased risk of experiencing a stroke. Further, patients with type 2 diabetes who have a stroke have worse outcomes compared with those without type 2 diabetes.1 While secondary prevention strategies and the quality of care of patients with type 2 diabetes and concomitant coronary artery disease have been well-studied,2 less is known about the management of patients with type 2 diabetes and cerebrovascular disease (e.g., stroke, transient ischemic attack, carotid artery disease).
Source: The American Journal of Medicine - July 21, 2022 Category: General Medicine Authors: Justin B. Echouffo-Tcheugui, Alexander Turchin, Robert S. Rosenson, Gregg C. Fonarow, Abhinav Goyal, James A. de Lemos, Suzanne V. Arnold Tags: Clinical Research Study Source Type: research
Long-term cardiac monitoring after embolic stroke of undetermined source. Search longer – look harder
Ischemic stroke is a heterogeneous syndrome which may result from several causes such as atherosclerosis, small vessel disease and atrial fibrillation.1 Despite an extensive diagnostic work-up during the acute or chronic phase of the ischemic stroke, the cause of ischemic stroke remains unexplained for 20% of patients, termed cryptogenic stroke. 2 3
Source: The American Journal of Medicine - May 14, 2022 Category: General Medicine Authors: Dimitrios Sagris, Stephanie L Harrison, Benjamin J.R Buckley, George Ntaios, Gregory Y.H Lip Source Type: research
Microvascular dysfunction as a systemic disease: A review of the evidence
Microvascular dysfunction describes a varied set of conditions which includes vessel destruction, abnormal vasoreactivity, in situ thrombosis, and fibrosis which ultimately results in tissue damage and progressive organ failure. Microvascular dysfunction has a wide array of clinical presentations, ranging from ischemic heart disease to renal failure, stroke, blindness, pulmonary arterial hypertension, and dementia. An intriguing unifying hypothesis suggests that microvascular dysfunction of specific organs is an expression of a systemic illness that worsens with age and is accelerated by vascular risk factors.
Source: The American Journal of Medicine - April 22, 2022 Category: General Medicine Authors: Daniel S. Feuer, Eileen M. Handberg, Borna Mehrad, Janet Wei, C. Noel Bairey Merz, Carl J. Pepine, Ellen C. Keeley Tags: Review article Source Type: research
Oral Anticoagulant Use for Patients with Atrial Fibrillation with Concomitant Anemia and/or Thrombocytopenia
Atrial fibrillation is the most common sustained cardiac arrhythmia in clinical practice, which is associated with an increased risk of thromboembolism, heart failure and mortality.1 Previous studies in atrial fibrillation patients have reported that abnormal hemoglobin and platelet counts may be associated with adverse events. However, these studies that specifically examined the associations between hemoglobin and platelet levels and adverse outcomes reported conflicting data.2-5 Although warfarin effectively reduces the risk of ischemic stroke by 64% compared to placebo/control,6 and non-vitamin K antagonist oral antico...
Source: The American Journal of Medicine - April 2, 2022 Category: General Medicine Authors: Yung-Hsin Yeh, Yi-Hsin Chan, Shao-Wei Chen, Shang-Hung Chang, Chun-Li Wang, Chi-Tai Kuo, Gregory Y.H. Li, Shih-Ann Chen, Tze-Fan Chao Tags: Clinical Research Study Source Type: research
Polycythemia Vera Presenting as ST-Segment Elevation Myocardial Infarction
An 80-year-old woman with a history of hypertension, pre-diabetes, chronic kidney disease (stage 3b), and a remote ischemic stroke without residual deficits presented to the emergency department complaining of several hours of epigastric discomfort and malaise. An electrocardiogram (EKG) performed at triage revealed normal sinus rhythm with>1 mm ST segment elevation in leads V4-6 and lead 1, reciprocal ST depression in aVR, and Q waves in V1 and V2 (Figure 1). The troponin I was elevated to 1.66 ng/mL (reference range
Source: The American Journal of Medicine - March 31, 2022 Category: General Medicine Authors: Eric Hirsch, Lindor Qunaj, Azeem Latib, Benjamin Galen Tags: Diagnostic Dilemma Source Type: research
Ischemic stroke due to metastatic cervical bone tumor: the importance of ‘peripheral vision’
To the Editor:
Source: The American Journal of Medicine - March 16, 2022 Category: General Medicine Authors: Akiyuki Hiraga, Satoshi Kuwabara Source Type: research
Blood Pressure Trajectories and Outcomes for Veterans Presenting at VA Medical Centers with a Stroke or Transient Ischemic Attack
Blood pressure control has been shown to reduce risk of vascular events and mortality after an ischemic stroke or transient ischemic attack (TIA). Yet, questions remain about effectiveness, timing, and targeted blood pressure reduction.
Source: The American Journal of Medicine - March 12, 2022 Category: General Medicine Authors: Greg Arling, Anthony Perkins, Laura J. Myers, Jason J. Sico, Dawn M. Bravata Tags: Clinical Research Study Source Type: research
Peripheral Arterial Disease, Stroke, and Mortality in Patients with Atrial Fibrillation
I read the paper by Vitalis et al1 with great interest. The authors assessed the impact of peripheral arterial disease on mortality and stroke in patients with atrial fibrillation. The adjusted hazard ratio (HR) (95% confidence interval [CI]) of peripheral arterial disease in patients with atrial fibrillation for all-cause mortality was 1.34 (1.06-1.70). In addition, the adjusted HR (95% CI) of peripheral arterial disease in patients with nonanticoagulated atrial fibrillation for ischemic stroke was 3.37 (1.25-9.09).
Source: The American Journal of Medicine - February 1, 2022 Category: General Medicine Authors: Tomoyuki Kawada Tags: Letter Source Type: research
Management of Atherosclerotic Carotid Artery Disease. A Brief Overview and Update
The objective of this review is to outline the clin ical presentation of symptomatic carotid artery stenosis and the risk factors associated with development of carotid artery stenosis, and then summarize the current evidence-based medical treatment modalities, along with available surgical and endovascular therapies.
Source: The American Journal of Medicine - October 31, 2021 Category: General Medicine Authors: Sara Hassani, Marc Fisher Tags: Review Source Type: research
Management of Atherosclerotic Carotid Artery Disease: A Brief Overview and Update
The objective of this review is to outline the clinical presentation of symptomatic carotid artery stenosis and the risk factors associated with development of carotid artery stenosis and then summarize the current evidence-based medical treatment modalities, along with available surgical and endovascular therapies.
Source: The American Journal of Medicine - October 31, 2021 Category: General Medicine Authors: Sara Hassani, Marc Fisher Tags: Review Source Type: research
Effects of Anticoagulation on Low-Density Lipoprotein-Cholesterol and Ischemic Stroke in Patients with Nonvalvular Atrial Fibrillation
The study by Omelchenko et al1 concluded that, unlike the general population, low-density lipoprotein-cholesterol (LDL-C) levels were not associated with ischemic stroke risk among patients with atrial fibrillation treated with direct oral anticoagulants (DOACs). To arrive at this conclusion, they retrospectively analyzed data of 21,229 patients with a first-time diagnosis of nonvalvular atrial fibrillation treated with DOACs categorized according to the congestive heart failure, hypertension, age ≥75 years, diabetes mellitus, stroke or transient ischemic attack (TIA), vascular disease, age 65 to 74 years, sex category, ...
Source: The American Journal of Medicine - September 28, 2021 Category: General Medicine Authors: Zeeshan H. Ismail, Zekarias T. Asnake, Joshua K. Salabei Tags: Letter Source Type: research
An updated review of the efficacy and safety of direct oral anticoagulants in treatment of left ventricular thrombus
Left ventricular (LV) thrombus is a potentially serious complication affecting males and females with ischemic and non-ischemic cardiomyopathy - specifically after acute myocardial infarctions of the anterior left ventricular wall, and long-standing tachyarrhythmias, respectively1. LV thrombi pose significant risks for systemic embolization and devastating stroke events, while also demanding a treatment carrying inherit risks of its own. It is therefore imperative to have accurate detection of these ventricular thrombi and an appropriate understanding of the risks and benefits regarding management.
Source: The American Journal of Medicine - August 29, 2021 Category: General Medicine Authors: Kevin A. Honan, Arjun Jogimahanti, Tarif Khair Tags: Review, meta-analysis Source Type: research
Ischemic Stroke
This concise review of the epidemiology, pathophysiology, evaluation, acute management, and prevention of ischemic stroke targets internists, family practicioners, and emergency physicians who manage patient with stroke.
Source: The American Journal of Medicine - August 26, 2021 Category: General Medicine Authors: Steven K. Feske Tags: Review Source Type: research
