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Relation of Diastolic Blood Pressure and Coronary Artery Calcium to Coronary Events and Outcomes (From the Multi-Ethnic Study of Atherosclerosis)
Diastolic blood pressure has a J-curve relationship with coronary heart disease and death. Because this association is thought to reflect reduced coronary perfusion at low diastolic blood pressure, we hypothesized that the J-curve would be most pronounced among persons with coronary artery calcium. Among 6,811 participants from the Multi-Ethnic Study of Atherosclerosis, we used Cox models to examine if diastolic blood pressure category is associated with coronary heart disease events, stroke, and mortality.
Source: The American Journal of Cardiology - August 8, 2017 Category: Cardiology Authors: Faisal Rahman, Mahmoud Al Rifai, Michael J. Blaha, Khurram Nasir, Matthew J Budoff, Bruce M. Psaty, Wendy S. Post, Roger S. Blumenthal, John W. McEvoy Source Type: research

Impact of Co-morbidity on the Risk of First-Time Myocardial Infarction, Stroke, or Death After Single-Photon Emission Computed Tomography Myocardial Perfusion Imaging
In conclusion, independently of co-morbidity level, an abnormal SPECT MPI scan was associated with an increased 10-year risk of myocardial infarction and all-cause death but not stroke.
Source: The American Journal of Cardiology - June 9, 2014 Category: Cardiology Authors: Astrid Blicher Schelde, Morten Schmidt, Morten Madsen, Karin Lottrup Petersen, Søren Steen Nielsen, Jørgen Frøkiær, Henrik Toft Sørensen, Christian Fynbo Christiansen Tags: Coronary Artery Disease Source Type: research

Usefulness of Local Delivery of Thrombolytics Before Thrombectomy in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention (the Delivery of Thrombolytics Before Thrombectomy in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention DISSOLUTION Randomized Trial)
In conclusion, local, intrathrombus delivery of thrombolytics before manual thrombectomy improved the postprocedural coronary flow and myocardial perfusion and the 6-month clinical outcomes.
Source: The American Journal of Cardiology - May 28, 2013 Category: Cardiology Authors: Cesare Greco, Francesco Pelliccia, Gaetano Tanzilli, Maria Denitza Tinti, Paola Salenzi, Cristina Cicerchia, Michele Schiariti, Ferdinando Franzoni, Giuseppe Speziale, Pietro Gallo, Carlo Gaudio Tags: Coronary Artery Disease Source Type: research

Non-Invasive Monitoring of Cerebral Perfusion During Transcatheter Aortic Valve Implantation Procedure
We read the report by Nuis et al on the frequency and cause of stroke during and after transcatheter aortic valve implantation (TAVI). The investigators reported a 9% stroke incidence (19 of 214 patients), with early (24 hours, mean 3.5 days after TAVI) stroke in 11 patients. They used brain computed tomographic findings to further analyze the cause of stroke. Interestingly, they found that 26% of strokes (5 patients) revealed lacunar lesions, which is widely regarded as caused by cerebral hypoperfusion in the presence of local atherosclerosis. Therefore, the investigators implied that all efforts should be made during TA...
Source: The American Journal of Cardiology - January 4, 2013 Category: Cardiology Authors: Cathy De Deyne, Ingrid Meex, Frank Jans, Kim Engelen, Herbert Gutermann, Jo Dens Tags: Readers' Comments Source Type: research