• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Comparison of Outcome of Coronary Artery Bypass Grafting versus Drug-Eluting Stent Implantation for Non-ST-Elevation Acute Coronary Syndrome
There is limited data comparing effectiveness of coronary artery bypass grafting (CABG) versus percutaneous coronary intervention (PCI) with drug-eluting stents (DES) in patients with non-ST-elevation acute coronary syndromes (NSTE-ACS). We compared the long-term outcomes of the two revascularization strategies in 1,246 patients presented with NSTE-ACS for left main or multivessel coronary artery disease (CAD). Data were pooled from the BEST, PRECOMBAT, and SYNTAX trials. The primary outcome was a composite of death from any causes, myocardial infarction, or stroke.
Source: The American Journal of Cardiology - May 10, 2017 Category: Cardiology Authors: Mineok Chang, Cheol Whan Lee, Jung-Min Ahn, Rafael Cavalcante, Yohei Sotomi, Yoshinobu Onuma, Minkyu Han, Duk-Woo Park, Soo-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Seong-Wook Park, Patrick W. Serruys, Seung-Jung Park Source Type: research

Meta-Analysis of Percutaneous Coronary Intervention versus Coronary Artery Bypass Grafting in Left Main Coronary Arterial Disease
Despite the increase in use of percutaneous coronary intervention (PCI) in left main (LM) coronary disease, its efficacy compared with coronary artery bypass grafting (CABG) is unclear. We performed a meta-analysis of randomized controlled trials to assess the optimal revascularization strategy. Our search yielded 8 studies reporting relevant outcomes which were pooled using the inverse-variance method, and the hazard ratio (HR) was calculated. The primary outcome was all-cause mortality, myocardial infarction (MI), or stroke (MACE), and the secondary outcome was death/MI/stroke/repeat revascularization (expanded MACE).
Source: The American Journal of Cardiology - March 28, 2017 Category: Cardiology Authors: Abdur R. Khan, Harsh Golwala, Avnish Tripathi, Haris Riaz, Arnav Kumar, Michael P. Flaherty, Deepak L. Bhatt Source Type: research

Coronary Artery Bypass Grafting Versus Drug-Eluting Stents Implantation for Prior Myocardial Infarction
Patients with prior myocardial infarction (MI) have a high risk of recurrence. Little is known about the effectiveness of coronary artery bypass grafting (CABG) versus percutaneous coronary intervention (PCI) with drug-eluting stents (DES) in patients with a prior MI and left main or multivessel coronary artery disease (CAD). We compared long-term outcomes of these two strategies in 672 patients with prior MI and left main or multivessel CAD, who underwent CABG (n=349) or PCI with DES (n=323). A pooled database from the BEST, PRECOMBAT, and SYNTAX trials was analyzed, and the primary outcome was a composite of death from a...
Source: The American Journal of Cardiology - April 19, 2016 Category: Cardiology Authors: Mineok Chang, Cheol Whan Lee, Jung-Min Ahn, Rafael Cavalcante, Yohei Sotomi, Yoshinobu Onuma, Yaping Zeng, Duk-Woo Park, Soo-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Seong-Wook Park, Patrick W. Serruys, Seung-Jung Park Source Type: research

Comparison of Five-Year Outcome of Percutaneous Coronary Intervention With Coronary Artery Bypass Grafting in Triple-Vessel Coronary Artery Disease (from the Coronary Revascularization Demonstrating Outcome Study in Kyoto PCI/CABG Registry Cohort-2)
Studies evaluating long-term (≥5 years) outcomes of percutaneous coronary intervention (PCI) using drug-eluting stents compared with coronary artery bypass grafting (CABG) in patients with triple-vessel coronary artery disease (TVD) are still limited. We identified 2,978 patients with TVD (PCI: n = 1,824, CABG: n = 1,154) of 15,939 patients with first coronary revascularization enrolled in the Coronary Revascularization Demonstrating Outcome Study in Kyoto PCI/CABG Registry Cohort-2. The primary outcome measure in the present analysis was a composite of death, myocardial infarction (MI), and stroke.
Source: The American Journal of Cardiology - April 6, 2015 Category: Cardiology Authors: Hiroki Shiomi, Takeshi Morimoto, Yutaka Furukawa, Yoshihisa Nakagawa, Junichi Tazaki, Ryuzo Sakata, Hitoshi Okabayashi, Michiya Hanyu, Mitsuomi Shimamoto, Noboru Nishiwaki, Tatsuhiko Komiya, Takeshi Kimura, the CREDO-Kyoto PCI/ CABG Registry Cohort-2 Inve Tags: Coronary Artery Disease Source Type: research

Comparison of Five-year Outcome of Percutaneous Coronary Intervention to Coronary Artery Bypass Grafting in Triple Vessel Coronary Artery Disease (From CREDO-Kyoto PCI/CABG Registry Cohort-2)
Studies evaluating long-term (>=5-year) outcomes of percutaneous coronary intervention (PCI) using drug-eluting stents compared with coronary artery bypass grafting (CABG) in patients with triple vessel coronary artery disease (TVD) are still limited. We identified 2978 patients with TVD (PCI: N=1824, CABG: N=1154) among 15939 patients with first coronary revascularization enrolled in the CREDO-Kyoto PCI/CABG registry cohort-2. The primary outcome measure in the current analysis was a composite of death, myocardial infarction (MI), and stroke.
Source: The American Journal of Cardiology - April 6, 2015 Category: Cardiology Authors: Hiroki Shiomi, Takeshi Morimoto, Yutaka Furukawa, Yoshihisa Nakagawa, Junichi Tazaki, Ryuzo Sakata, Hitoshi Okabayashi, Michiya Hanyu, Mitsuomi Shimamoto, Noboru Nishiwaki, Tatsuhiko Komiya, Takeshi Kimura, CREDO-Kyoto PCI/ CABG registry cohort-2 investig Source Type: research

OP-055 Twelve Year Followup for Managing Coronary Artery Disease Using a Nutrigenomics Based Diet and Supplement Program and Quarterly Assessment of Biomarkers
Coronary Artery Disease (CAD) is thought to be progressive; standard treatment protocols call for instituting/instructing a low fat/low cholesterol diet program, exercise, and lipid lowering agents in an effort to slow the onset of recurrent MI's, stents, CABG's, stroke, or death. This results in an approximate 30-40% new event rate in 5 yrs.
Source: The American Journal of Cardiology - March 12, 2015 Category: Cardiology Authors: Steven Robert Gundry, Jean Epstein Tags: Oral Abstract Source Type: research

Predictors of Stroke Associated with Coronary Artery Bypass Grafting in Patients with Diabetes Mellitus and Multivessel Coronary Artery Disease
This study assesses demographic and clinical variables associated with perioperative and late stroke in diabetes mellitus patients following multivessel coronary artery bypass grafting (CABG). FREEDOM is the largest randomized trial of diabetic patients undergoing multivessel CABG. FREEDOM patients had improved survival free of death, myocardial infarction or stroke and increased overall survival following CABG compared to percutaneous intervention (PCI). However, the stroke rate was greater following CABG than PCI.
Source: The American Journal of Cardiology - February 20, 2015 Category: Cardiology Authors: Michael J. Domanski, Michael E. Farkouh, Victor Zak, Steven Feske, Donald Easton, Jesse Weinberger, Martial Hamon, Jorge Escobedo, Peter Shrader, Flora S. Siami, Valentin Fuster Source Type: research

Relation of Major Depression to Survival After Coronary Artery Bypass Grafting
In conclusion, we found a strong and significant association between depression and long-term survival in patients with established ischemic heart disease who underwent CABG. Depression was also associated with an increased risk for a combination of death or rehospitalization for heart failure, myocardial infarction, or stroke.
Source: The American Journal of Cardiology - June 20, 2014 Category: Cardiology Authors: Malin Stenman, Martin J. Holzmann, Ulrik Sartipy Tags: Coronary Artery Disease Source Type: research

Comparison of 30-Day and 5-Year Outcomes of Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Patients Aged ≤50 Years (the Coronary aRtery diseAse in younG adultS Study)
Data on the outcome of young patients after coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) are scarce. Data on 2,209 consecutive patients aged ≤50 years who underwent CABG or PCI were retrospectively collected from 15 European institutions. PCI and CABG had similar 30-day mortality rates (0.8% vs 1.4%, p = 0.27), late survival (at 5 years, 97.8% vs 94.9%, p = 0.082), and freedom from stroke (at 5 years, 98.0% and 98.0%, p = 0.731). PCI was associated with significantly lower freedom from major adverse cardiac and cerebrovascular events (at 5 years, 73.9% vs 85.0%, p
Source: The American Journal of Cardiology - May 5, 2014 Category: Cardiology Authors: Fausto Biancari, Tomas Gudbjartsson, Jouni Heikkinen, Vesa Anttila, Timo Mäkikallio, Anders Jeppsson, Linda Thimour-Bergström, Carmelo Mignosa, Antonino S. Rubino, Kari Kuttila, Jarmo Gunn, Jan-Ola Wistbacka, Kari Teittinen, Kari Korpilahti, Francesco O Tags: Coronary Artery Disease Source Type: research

Comparison of Hybrid Coronary Revascularization Versus Coronary Artery Bypass Grafting in Patients ≥65 Years With Multivessel Coronary Artery Disease
In this study, patients aged ≥65 years were included who underwent HCR at an academic center from October 2003 to September 2013. These patients were matched 1:4 to similar patients treated with coronary artery bypass grafting (CABG) using a propensity-score matching algorithm. Conditional logistic regression and Cox regression stratified on matched pairs were performed to evaluate the association between HCR and CABG, and 30-day major adverse cardiovascular and cerebrovascular events (a composite of mortality, myocardial infarction, and stroke), periprocedural complications, and 3-year all-cause mortality. Of 715 patien...
Source: The American Journal of Cardiology - May 5, 2014 Category: Cardiology Authors: Ralf E. Harskamp, John D. Puskas, Jan G. Tijssen, Patrick F. Walker, Henry A. Liberman, Renato D. Lopes, Thomas A. Vassiliades, Eric D. Peterson, Michael E. Halkos Tags: Coronary Artery Disease Source Type: research

Impact of Dual Antiplatelet Therapy on Outcomes Among Aspirin-Resistant Patients Following Coronary Artery Bypass Grafting
This study was designed to define the impact of dual antiplatelet therapy (dAPT) on clinical outcomes among aspirin-resistant patients who underwent coronary artery surgery. We randomly assigned 219 aspirin-resistant patients according to multiple electrode aggregometry to receive clopidogrel (75 mg) plus aspirin (300 mg) or aspirin-monotherapy (300 mg). The primary end point was a composite outcome of all-cause death, nonfatal myocardial infarction, stroke, or cardiovascular hospitalization assessed at 6 months postoperatively. The primary end point occurred in 6% of patients assigned to dAPT and 10% of patients rando...
Source: The American Journal of Cardiology - March 3, 2014 Category: Cardiology Authors: Hrvoje Gasparovic, Mate Petricevic, Tomislav Kopjar, Zeljko Djuric, Lucija Svetina, Bojan Biocina Tags: Coronary Artery Disease Source Type: research

Comparison of Intermediate-Term Outcomes of Coronary Artery Bypass Grafting Versus Drug-Eluting Stents for Patients ≥75 Years of Age
In conclusion, older patients experienced similar mortality and stroke/MI/mortality rates for CABG and PCI with DES, although repeat revascularization rates were higher for patients undergoing PCI with DES.
Source: The American Journal of Cardiology - December 16, 2013 Category: Cardiology Authors: Edward L. Hannan, Ye Zhong, Peter B. Berger, Gary Walford, Jeptha P. Curtis, Chuntao Wu, Ferdinand J. Venditti, Robert S.D. Higgins, Craig R. Smith, Stephen J. Lahey, Spencer B. King Tags: Coronary Artery Disease Source Type: research

Minimal Changes in Postoperative Creatinine Values and Early and Late Mortality and Cardiovascular Events After Coronary Artery Bypass Grafting
In conclusion, already a minimal increase in the postoperative serum creatinine level after CABG was independently associated with long-term all-cause mortality and cardiovascular outcomes, regardless of preoperative renal function.
Source: The American Journal of Cardiology - October 30, 2013 Category: Cardiology Authors: Marcus Liotta, Daniel Olsson, Ulrik Sartipy, Martin J. Holzmann Tags: Coronary Artery Disease Source Type: research

Association Between Intraprocedural Thrombotic Events and Adverse Outcomes After Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction (a Harmonizing Outcomes With RevasculariZatiON and Stents in Acute Myocardial Infarction HORIZONS-AMI Substudy)
The present study sought to determine the extent to which adverse angiographic events encountered during percutaneous coronary intervention for ST-segment elevation myocardial infarction (STEMI) are associated with adverse clinical outcomes. Patients with STEMI represent a cohort at particularly high risk of intraprocedural thrombotic events (IPTEs). The overall frequency and implications of IPTEs occurring in patients with STEMI have not been systematically quantified in previous studies. A total of 3,163 patients undergoing primary percutaneous coronary intervention with stent implantation for STEMI in the Harmonizing Ou...
Source: The American Journal of Cardiology - October 28, 2013 Category: Cardiology Authors: Ajay J. Kirtane, Prabhdeep Sandhu, Roxana Mehran, Margaret McEntegart, Ecaterina Cristea, Sorin J. Brener, Ke Xu, Martin Fahy, Philippe Généreux, Jeffrey D. Wessler, Gregg W. Stone Tags: Coronary Artery Disease Source Type: research

Usefulness of Brachial Artery Flow-Mediated Dilation to Predict Long-Term Cardiovascular Events in Subjects Without Heart Disease
Endothelial dysfunction is considered an important prognostic factor in atherosclerosis. To determine the long-term association of brachial artery flow-mediated dilation (FMD) and adverse cardiovascular (CV) events in healthy subjects, we prospectively assessed brachial FMD in 618 consecutive healthy subjects with no apparent heart disease, 387 men (63%), and mean age 54 ± 11 years. After overnight fasting and discontinuation of all medications for ≥12 hours, FMD was assessed using high-resolution linear array ultrasound. Subjects were divided into 2 groups: FMD ≤11.3% (n = 309) and>11.3% (n = 309), where 11.3% is...
Source: The American Journal of Cardiology - October 28, 2013 Category: Cardiology Authors: Michael Shechter, Alon Shechter, Nira Koren-Morag, Micha S. Feinberg, Liran Hiersch Tags: Miscellaneous Source Type: research

Pages: 1  2  3