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Comparison of Procedural Complications With Versus Without Interventional Cardiology Fellows-in-Training During Contemporary Percutaneous Coronary Intervention
In conclusion, in contemporary practice at a large academic medical center, PCI complication rates were not adversely affected by the presence of an ICFIT.
Source: The American Journal of Cardiology - October 28, 2013 Category: Cardiology Authors: Joshua M. Stolker, Drew S. Allen, David J. Cohen, Kevin F. Kennedy, Steven B. Laster, Andrew D. Frutkin, Sameer K. Mehta, Kelly R. O'Neal, Steven P. Marso Tags: Coronary Artery Disease Source Type: research

Assessment of Device Related Thrombus and Associated Clinical Outcomes with the WATCHMAN Left Atrial Appendage Closure Device for Embolic Protection in Patients with Atrial Fibrillation (From the PROTECT-AF Trial)
Left atrial appendage (LAA) closure with the WATCHMAN device is an alternative to anticoagulation for stroke prevention in selected patients with atrial fibrillation (AF). LA device related thrombus (DRT) is poorly defined and understood. We aimed to 1) develop consensus echocardiographic diagnostic criteria for DRT 2) estimate the incidence of DRT and 3) determine clinical event rates in patients with DRT. In Phase 1 (Training), a training manual was developed and reviewed by 3 echocardiographers with LAA closure device experience.
Source: The American Journal of Cardiology - February 1, 2016 Category: Cardiology Authors: Michael L. Main, Dali Fan, Vivek Y. Reddy, David R. Holmes, Nicole T. Gordon, Tina R. Coggins, John A. House, Lawrence Liao, Dawn Rabineau, George G. Latus, Kenneth C. Huber, Horst Sievert, Richard F. Wright, Shephal K. Doshi, Pamela S. Douglas Source Type: research

Assessment of Device-Related Thrombus and Associated Clinical Outcomes With the WATCHMAN Left Atrial Appendage Closure Device for Embolic Protection in Patients With Atrial Fibrillation (from the PROTECT-AF Trial)
Left atrial appendage closure with the WATCHMAN device is an alternative to anticoagulation for stroke prevention in selected patients with atrial fibrillation (AF). LA device-related thrombus (DRT) is poorly defined and understood. We aimed to (1) develop consensus echocardiographic diagnostic criteria for DRT; (2) estimate the incidence of DRT; and (3) determine clinical event rates in patients with DRT. In phase 1 (training), a training manual was developed and reviewed by 3 echocardiographers with left atrial appendage closure device experience.
Source: The American Journal of Cardiology - February 1, 2016 Category: Cardiology Authors: Michael L. Main, Dali Fan, Vivek Y. Reddy, David R. Holmes, Nicole T. Gordon, Tina R. Coggins, John A. House, Lawrence Liao, Dawn Rabineau, George G. Latus, Kenneth C. Huber, Horst Sievert, Richard F. Wright, Shephal K. Doshi, Pamela S. Douglas Tags: Arrhythmias and Conduction Disturbances Source Type: research

Usefulness of Multiple Biomarkers for Predicting Incident Major Adverse Cardiac Events in Patients Undergoing Diagnostic Coronary Angiography (From the Catheter Sampled Blood Archive in Cardiovascular Diseases CASABLANCA Study)
We sought to develop a multiple biomarker approach for prediction of incident major adverse cardiovascular events (MACE; composite of cardiovascular death, myocardial infarction and stroke) in patients referred for coronary angiography. In a 649-participant training cohort, predictors of MACE within one year were identified using least-angle regression; over fifty clinical variables and 109 biomarkers were analyzed. Predictive models were generated using LASSO with logistic regression. A score derived from the final model was developed and evaluated with a 278-patient validation set during a median of 3.6 years follow up.
Source: The American Journal of Cardiology - April 13, 2017 Category: Cardiology Authors: Cian P. McCarthy, Roland R.J. van Kimmenade, Hanna K. Gaggin, Mandy L. Simon, Nasrien E. Ibrahim, Parul Gandhi, Noreen Kelly, Shweta R. Motiwala, Arianna M. Belcher, Jamie Harisiades, Craig A. Magaret, Rhonda F. Rhyne, James L. Januzzi Source Type: research

Usefulness of Multiple Biomarkers for Predicting Incident Major Adverse Cardiac Events in Patients Who Underwent Diagnostic Coronary Angiography (from the Catheter Sampled Blood Archive in Cardiovascular Diseases CASABLANCA Study)
We sought to develop a multiple biomarker approach for prediction of incident major adverse cardiac events (MACE; composite of cardiovascular death, myocardial infarction, and stroke) in patients referred for coronary angiography. In a 649-participant training cohort, predictors of MACE within 1 year were identified using least-angle regression; over 50 clinical variables and 109 biomarkers were analyzed. Predictive models were generated using least absolute shrinkage and selection operator with logistic regression.
Source: The American Journal of Cardiology - April 13, 2017 Category: Cardiology Authors: Cian P. McCarthy, Roland R.J. van Kimmenade, Hanna K. Gaggin, Mandy L. Simon, Nasrien E. Ibrahim, Parul Gandhi, Noreen Kelly, Shweta R. Motiwala, Arianna M. Belcher, Jamie Harisiades, Craig A. Magaret, Rhonda F. Rhyne, James L. Januzzi Tags: Coronary Artery Disease Source Type: research