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Safety and Effect of Very Low Levels of Low-Density Lipoprotein Cholesterol on Cardiovascular Events
In conclusion, clinical trial evidence demonstrating the efficacy and safety of LDL cholesterol lowering to a very low level is essential to ascertain the benefits and risks in reducing the residual risk of vascular disease.
Source: The American Journal of Cardiology - February 1, 2013 Category: Cardiology Authors: John C. LaRosa, Terje R. Pedersen, Ransi Somaratne, Scott M. Wasserman Tags: Review Source Type: research

Applying Antithrombotic Therapies to Improve Outcomes in Patients With Atrial Fibrillation
Abstract: Approximately 15% to 25% or 75,000 ischemic strokes are attributed to atrial fibrillation annually within the United States. Atrial fibrillation is the most frequently diagnosed cardiac arrhythmia and affects more than 2.66 million Americans. Moreover, atrial fibrillation is associated with a 1.5 to 1.9-fold higher risk of death due to its strong correlation with thromboembolic events. Because of the attributed increased morbidity and mortality, challenges that concern identification of patients at risk for thromboembolic events from atrial fibrillation must be addressed. These challenges include compliance to pe...
Source: The American Journal of Cardiology - August 1, 2013 Category: Cardiology Authors: Chris Cannon, Michael D. Ezekowitz, Christopher Granger Tags: Multimedia Activities Source Type: research

Prevalence of Memory Disorders in Ambulatory Patients Aged ≥70 Years With Chronic Heart Failure (from the EFICARE Study)
The aim of this multicenter observational study conducted in France was to determine the prevalence of memory impairment in ambulatory patients aged ≥70 years with chronic heart failure (HF). Two hundred ninety-one cardiologists recruited 912 ambulatory patients with HF (mean age 79.2 ± 5.8 years) from January to November 2009. Memory was evaluated by the delayed-recall Memory Impairment Screen (MIS-D). Memory impairment was defined as MIS-D score ≤6 and severe memory impairment as MIS-D score ≤4. HF was diagnosed 4.4 ± 4.8 years earlier and mean left ventricular ejection fraction was 43.6 ± 12.0%. Memory impai...
Source: The American Journal of Cardiology - January 16, 2014 Category: Cardiology Authors: Olivier Hanon, Jean-Sébastien Vidal, Pascal de Groote, Michel Galinier, Richard Isnard, Damien Logeart, Michel Komajda Tags: Heart Failure Source Type: research

Use of Evidence-Based Therapy for Cardiovascular Risk Factors in Canadian Outpatients with Atrial Fibrillation
Using data collected from 2 national atrial fibrillation (AF) primary care physician chart audits (Facilitating REview and EDucation to OptiMize stroke prevention in Atrial Fibrillation [FREEDOM AF] and CO-ordinated National Network to Engage physicians in the Care and Treatment of patients with Atrial Fibrillation [CONNECT AF]), we evaluated the frequency of, and factors associated with, the use of cardiovascular (CV) evidence-based therapies in Canadian AF outpatients with at least one CV risk factor or comorbidity.
Source: The American Journal of Cardiology - May 31, 2017 Category: Cardiology Authors: Alexandra Silberberg, Mary K. Tan, Andrew T. Yan, Paul Angaran, Paul Dorian, Claudia Bucci, Jean C. Gregoire, Alan D. Bell, David J. Gladstone, Martin S. Green, Peter L. Gross, Allan Skanes, Andrew M. Demchuk, Charles R. Kerr, L. Brent Mitchell, Jafna L. Source Type: research

Influence of Sociodemographic Factors and Provider Specialty on Anticoagulation Prescription Fill Patterns and Outcomes in Atrial Fibrillation
We examined anticoagulant fills in 223,891 patients with incident non-valvular AF (mean age=71 years; 44% female; 84% white; 9% black; 5% Hispanic; 2% Asian) from the Optum Clinformatics database (2009-2014). Provider specialty and filled anticoagulant prescriptions 3 months prior to and 6 months after AF diagnosis were obtained.
Source: The American Journal of Cardiology - April 30, 2018 Category: Cardiology Authors: Wesley T. O'Neal, Pratik B. Sandesara, J'Neka S. Claxton, Richard F. MacLehose, Lin Y. Chen, Lindsay G.S. Bengtson, Alanna M. Chamberlain, Faye L. Norby, Pamela L. Lutsey, Alvaro Alonso Source Type: research

Is Improving Educational Attainment Key to Reducing the Burden Because of Cardiovascular Diseases?
Cardiovascular diseases (CVDs) impose a substantial global public health burden, accounting for significant mortality and disability worldwide, particularly because of conditions like coronary heart disease and stroke. The economic consequences of CVDs, including healthcare expenses, decreased productivity, and diminished quality of life, further contribute to this burden. Lifestyle factors such as unhealthy diets, physical inactivity, tobacco use, and excessive alcohol consumption are closely associated with CVDs.
Source: The American Journal of Cardiology - August 1, 2023 Category: Cardiology Authors: Jari Antero Laukkanen, Setor Kwadzo Kunutsor Tags: Editorial Source Type: research