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Trends in the Longitudinal Utilization of Oral Anticoagulants Among Newly Diagnosed Atrial Fibrillation Patients With Commercial, Medicare, and Medicaid Insurance
Long-term oral anticoagulation (OAC) is recommended for stroke prevention for most patients with atrial fibrillation (AF) and elevated stroke risk.1 While trends in initiation of OAC have been described,2,3 long-term trends in utilization of OAC in patients continuously followed for AF have not been adequately explored. Some healthcare systems adapted anticoagulation services to respond to disruptions during the COVID-19 pandemic.4 We thus investigated how OACs were utilized in patients with newly diagnosed AF from 2018 to 2021 across 3 insurance types: Medicare, Medicaid, and commercial.
Source: The American Journal of Cardiology - July 28, 2023 Category: Cardiology Authors: Jun Soo Lee, Sola Han, Nicole L. Therrien, Chanhyun Park, Feijun Luo, Utibe R. Essien Tags: Brief report Source Type: research

Effect of Sodium-Glucose Cotransporter Inhibitors on Major Adverse Cardiovascular Events and Hospitalization for Heart Failure in Patients With Type 2 Diabetes Mellitus and Atrial Fibrillation
Sodium-glucose cotransporter 2 (SGLT2) inhibitors have been shown to lower cardiovascular morbidity and mortality in patients with type 2 diabetes mellitus (T2DM) and high cardiovascular risks. Here, we aimed to evaluate the effect of SGLT2 inhibitors on major adverse cardiovascular events (MACE), a composite of cardiovascular mortality, myocardial infarction, or ischemic stroke and hospitalization for heart failure in patients with T2DM and atrial fibrillation (AF). Using the Korean National Health Insurance Service database, we identified 40,268 patients with T2DM and AF who were newly prescribed oral hypoglycemic drugs ...
Source: The American Journal of Cardiology - July 7, 2022 Category: Cardiology Authors: Chang Hee Kwon, Ye-Jee Kim, Min-Ju Kim, Myung-Jin Cha, Min Soo Cho, Gi-Byoung Nam, Kee-Joon Choi, Jun Kim Source Type: research

Pattern and Impact of Off-label Underdosing of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation Who Are Indicated for Standard Dosing
With safety concerns about increasing bleeding, off-label underdosing of non-vitamin K antagonist anticoagulants (NOACs) is common in East Asian patients with atrial fibrillation (AF). We tried to investigate the pattern of NOAC underdosing and associated clinical outcomes in patients with AF who are indicated for standard dosing. Using the Korean National Health Insurance Service database, we evaluated 16568 patients with a new prescription of NOAC who are indicated for standard NOAC dosing and compared 4536 patients with warfarin with respect to thromboembolic events (ischemic stroke or systemic embolization), all-cause ...
Source: The American Journal of Cardiology - February 6, 2020 Category: Cardiology Authors: Min Soo Cho, Ji Eun Yun, Ji Jeong Park, Yun Jung Kim, Jessie Lee, Hyungmin Kim, Duk-Woo Park, Gi-Byoung Nam Source Type: research

Effect on Risk of Stroke and Acute Myocardial Infarction of Nonselective Nonsteroidal Anti-Inflammatory Drugs in Patients With Rheumatoid Arthritis
There are still debates on the association of increased cardiovascular risk with the use of nonsteroidal anti-inflammatory drugs (NSAIDs) in patients with rheumatoid arthritis (RA) because of inconsistent results. Therefore, our study aims to evaluate the transient effects of selective and nonselective NSAIDs on the risk of stroke and acute myocardial infarction (AMI) in patients with RA. We conducted a case-crossover study of 5,921 stroke or AMI patients with co-morbidity of RA. All cases were identified from the Taiwan National Health Insurance Database between January 1, 2006, and December 31, 2011, according to the Int...
Source: The American Journal of Cardiology - February 12, 2018 Category: Cardiology Authors: Yih-Ru Chen, Fang-I Hsieh, Chi-Ching Chang, Nai-Fang Chi, Hsin-Chiao Wu, Hung-Yi Chiou Source Type: research

Effect on Risk of Stroke and Acute Myocardial Infarction of Nonselective Nonsteroidal Anti-Inflammatory Drugs in Patients with Rheumatoid Arthritis
There are still debates on the association of increased cardiovascular risk with the use of nonsteroidal anti-inflammatory drugs (NSAIDs) in rheumatoid arthritis (RA) patients because of inconsistent results. Therefore, our study aims to evaluate the transient effects of selective and nonselective NSAIDs on the risk of stroke and acute myocardial infarction (AMI) in patients with RA. We conducted a case-crossover study of 5,921 stroke or AMI patients with comorbidity of RA. All cases were identified from the Taiwan National Health Insurance Database between January 1, 2006, through December 31, 2011 according to the Intern...
Source: The American Journal of Cardiology - February 12, 2018 Category: Cardiology Authors: Yih-Ru Chen, Fang-I Hsieh, Chi-Ching Chang, Nai-Fang Chi, Hsin-Chiao Wu, Hung-Yi Chiou Source Type: research

Trends in Ideal cardiovascular Health Metrics Among Employees of a Large Healthcare Organization (From the Baptist Health South Florida Employee Study)
The American Heart Association’s (AHA) 2020 goal is to improve the cardiovascular health (CVH) of people living in the United States by 20% and reduce mortality from cardiovascular diseases (CVD) and stroke by 20%. Given that 155 million adults are in the U.S workforce, and over 60% have employee-based insurance, workplace studies provide an important opportunity to assess, and potentially advance CVH through the use of comprehensive workplace wellness programs. Among a cohort of employees of the Baptist Health System, CVH was assessed annually during voluntary health fairs and health risk assessments (HRA) from 2011-201...
Source: The American Journal of Cardiology - December 13, 2015 Category: Cardiology Authors: Oluseye Ogunmoroti, Ovie Utuama, Erica S. Spatz, Maribeth Rouseff, Don Parris, Sankalp Das, Adnan Younus, Henry Guzman, Thinh Tran, Arthur Agatston, Theodore Feldman, Salim S. Virani, Wasim Maziak, Emir Veledar, Khurram Nasir Source Type: research