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Trends in the Longitudinal Utilization of Oral Anticoagulants Among Newly Diagnosed Atrial Fibrillation Patients With Commercial, Medicare, and Medicaid Insurance
Long-term oral anticoagulation (OAC) is recommended for stroke prevention for most patients with atrial fibrillation (AF) and elevated stroke risk.1 While trends in initiation of OAC have been described,2,3 long-term trends in utilization of OAC in patients continuously followed for AF have not been adequately explored. Some healthcare systems adapted anticoagulation services to respond to disruptions during the COVID-19 pandemic.4 We thus investigated how OACs were utilized in patients with newly diagnosed AF from 2018 to 2021 across 3 insurance types: Medicare, Medicaid, and commercial.
Source: The American Journal of Cardiology - July 28, 2023 Category: Cardiology Authors: Jun Soo Lee, Sola Han, Nicole L. Therrien, Chanhyun Park, Feijun Luo, Utibe R. Essien Tags: Brief report Source Type: research

Hemodynamic Profiles of Shock in Patients with COVID-19
Patients with serious COVID infections develop shock frequently. To characterize the hemodynamic profile of this cohort, 156 patients with COVID pneumonia and shock requiring vasopressors had interpretable echocardiography with measurement of ejection fraction (EF) by Simpson's rule and stroke volume (SV) by Doppler. RV systolic pressure (RVSP) was estimated from the tricuspid regurgitation peak velocity. Patients were divided into groups with low or preserved EF (EFL or EFP, cutoff ≤45%), and low or normal cardiac index (CIL or CIN, cutoff ≤2.2 L/min/m2).
Source: The American Journal of Cardiology - May 25, 2021 Category: Cardiology Authors: Steven M Hollenberg, Lucy Safi, Joseph E Parrillo, Matthew Fata, Brent Klinkhammer, Noha Gayed, Taya Glotzer, Ronaldo C. Go, Elli Gourna-Paleoudis, David Landers, Sameer Jamal, Neel Shah, Roshan Shah, Jana Tancredi, Zoltan G Turi Source Type: research

Relation of Cardiovascular Risk Factors to Mortality and Cardiovascular Events in Hospitalized Patients with Coronavirus Disease 2019 (From the Yale COVID-19 Cardiovascular Registry)
Individuals with established cardiovascular disease or a high burden of cardiovascular risk factors may be particularly vulnerable to develop complications from coronavirus disease 2019 (COVID-19). We conducted a prospective cohort study at a tertiary care center to identify risk factors for in-hospital mortality and major adverse cardiovascular events (MACE; a composite of myocardial infarction, stroke, new acute decompensated heart failure, venous thromboembolism, ventricular or atrial arrhythmia, pericardial effusion, or aborted cardiac arrest) among consecutively hospitalized adults with COVID-19, using multivariable b...
Source: The American Journal of Cardiology - February 1, 2021 Category: Cardiology Authors: Manan Pareek, Avinainder Singh, Lina Vadlamani, Maxwell Eder, Justin Pacor, Jakob Park, Zaniar Ghazizadeh, Alex Heard, Ana Sofia Cruz-Solbes, Roozbeh Nikooie, Chad Gier, Zain V. Ahmed, James V. Freeman, Judith Meadows, Kim G.E. Smolderen, Rachel Lampert, Source Type: research

Less Myocardial Infarction and Stroke Hospitalizations During Middle East Respiratory Syndrome Coronavirus Epidemic in Korea
Viral infections are known to impact coronary disease, and acute myocardial infarction (AMI) may be triggered by the inflammatory cytokine response to infection.1,2 Cytokines promote local inflammation in atherosclerotic plaques within the coronary artery, which can lead to plaque destabilization, rupture, and eventually AMI development. Psychological adversity, depression, stress at home or work, social isolation and loneliness are also known factors contributing to acute vascular event.3 Recent outbreaks of coronavirus (CoV), including severe acute respiratory syndrome (SARS), and Middle East respiratory syndrome (MERS) ...
Source: The American Journal of Cardiology - July 2, 2020 Category: Cardiology Authors: Cai De Jin, Moo Hyun Kim, Kwang Min Lee, Jong Sung Park, Dong Sik Jung, Sung-Cheol Yun, Victor Serebruany Source Type: research

Assessment of ST-Segment Elevation Myocardial Infarction Volume Trends During The COVID-19 Pandemic
Routine inpatient and outpatient health care has been greatly disrupted by the COVID-19 pandemic and both equipment and personnel have been redeployed in order to manage the crisis (https://www.cms.gov/newsroom/press-releases/cms-releases-recommendations-adult-elective-surgeries-non-essential-medical-surgical-and-dental). There have been anecdotal accounts (https://www.nytimes.com/2020/04/06/well/live/coronavirus-doctors-hospitals-emergency-care-heart-attack-stroke.html) and a publication (1) discussing the decrease in the number of ST-segment elevation myocardial infarction (STEMI) activiations.
Source: The American Journal of Cardiology - June 26, 2020 Category: Cardiology Authors: Amir S Lotfi, Alina Capatina, Aaron D Kugelmass Source Type: research

Reader's CommentsAssessment of ST-Segment Elevation Myocardial Infarction Volume Trends During The COVID-19 Pandemic
Routine inpatient and outpatient health care has been greatly disrupted by the COVID-19 pandemic and both equipment and personnel have been redeployed in order to manage the crisis (https://www.cms.gov/newsroom/press-releases/cms-releases-recommendations-adult-elective-surgeries-non-essential-medical-surgical-and-dental). There have been anecdotal accounts (https://www.nytimes.com/2020/04/06/well/live/coronavirus-doctors-hospitals-emergency-care-heart-attack-stroke.html) and a publication 1 discussing the decrease in the number of ST-segment elevation myocardial infarction (STEMI) activiations.
Source: The American Journal of Cardiology - June 26, 2020 Category: Cardiology Authors: Amir S Lotfi, Alina Capatina, Aaron D Kugelmass Source Type: research

Prevalence and Outcomes of Acute Ischemic Stroke Among Patients ≤ 50 Years of Age with Laboratory Confirmed COVID-19 Infection
The COVID-19 epidemic has led to an unpreceded disruption in health care systems worldwide. Concerns have been recently raised about young patients with COVID-19 presenting with large ischemic strokes.1 Data on stroke in COVID-19 patients remain limited to a few case reports.1 In this focused analysis, we investigated the incidence and outcomes of acute ischemic stroke in young adults using a multinational database.
Source: The American Journal of Cardiology - June 13, 2020 Category: Cardiology Authors: Frank Annie, Mark C. Bates, Aravinda Nanjundappa, Deepak L. Bhatt, Mohamad Alkhouli Source Type: research

Prevalence and Outcomes of Acute Ischemic Stroke Among Patients ≤50 Years of Age With Laboratory Confirmed COVID-19 Infection
The COVID-19 epidemic has led to an unpreceded disruption in health care systems worldwide. Concerns have been recently raised about young patients with COVID-19 presenting with large ischemic strokes.1 Data on stroke in COVID-19 patients remain limited to a few case reports.1 In this focused analysis, we investigated the incidence and outcomes of acute ischemic stroke in young adults using a multinational database.
Source: The American Journal of Cardiology - June 13, 2020 Category: Cardiology Authors: Frank Annie, Mark C. Bates, Aravinda Nanjundappa, Deepak L. Bhatt, Mohamad Alkhouli Source Type: research