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Source: Journal of Hypertension
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Total 283 results found since Jan 2013.
Low blood pressure and adverse outcomes in acute stroke: HeadPoST study explanations
Objective:
As uncertainties exist over underlying causes, we aimed to define the characteristics and prognostic significance of low blood pressure (BP) early after the onset of acute stroke.
Methods:
Post hoc analyzes of the international Head Positioning in acute Stroke Trial (HeadPoST), a pragmatic cluster-crossover randomized trial of lying flat versus sitting up in stroke patients from nine countries during 2015–2016. Associations of baseline BP and death or dependency [modified Rankin scale (mRS) scores 3–6] and serious adverse events (SAEs) at 90 days were assessed in generalized linear mixed models wi...
Source: Journal of Hypertension - January 7, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Stroke Source Type: research
Vascular and parenchymal lesions along with enhanced neurogenesis characterize the brain of asymptomatic stroke-prone spontaneous hypertensive rats
Conclusion:Appearance of vascular changes in SHRSPs, before any MRI-detectable brain lesion, is coupled to active neural proliferation in the SVZ. With disease progression, only newborn astrocytes can survive, likely because of the neurotoxicity triggered by brain oedema and oxidative stress.
Source: Journal of Hypertension - July 8, 2013 Category: Cardiology Tags: ORIGINAL PAPERS: Stroke Source Type: research
Impact of angiotensin-converting enzyme inhibition on platelet tissue factor expression in stroke-prone rats
Conclusion:
The current study shows for the first time that in hypertension the number of TF-positive megakaryocytes increases thus releasing in the circulation more platelets carrying a functionally active TF. AngII stimulates platelets to express TF.
Source: Journal of Hypertension - May 1, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Stroke Source Type: research
Early antihypertensive treatment and clinical outcomes in acute ischemic stroke: subgroup analysis by baseline blood pressure
Background:
We studied the effect of early antihypertensive treatment on death, major disability, and vascular events among patients with acute ischemic stroke according to their baseline SBP.
Methods:
We randomly assigned 4071 acute ischemic stroke patients with SBP between 140 and less than 220 mmHg to receive antihypertensive treatment or to discontinue all antihypertensive medications during hospitalization. A composite primary outcome of death and major disability and secondary outcomes were compared between treatment and control stratified by baseline SBP levels of less than 160, 160–179, and at least 180 ...
Source: Journal of Hypertension - May 1, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Stroke Source Type: research
Blood pressure excursions in acute ischemic stroke patients treated with intravenous thrombolysis
Conclusion:
BP excursions above guideline thresholds during the first 24 h following tPA administration for AIS are common and are independently associated with adverse clinical outcomes.
Source: Journal of Hypertension - January 7, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Stroke Source Type: research
Electrocardiographic left atrial abnormalities and risk of incident stroke in hypertensive patients with electrocardiographic left ventricular hypertrophy
Conclusion: Abnormal PTFV1, a marker of left atrial abnormality, was strongly associated with incident stroke in hypertensive patients, independent of in-treatment SBP and other predictors of incident stroke. This association, in the absence of detectable atrial fibrillation, suggests that an underlying atrial cardiopathy may cause left atrial thrombus formation and a subsequent stroke without intervening clinically recognized atrial fibrillation.
Source: Journal of Hypertension - August 5, 2016 Category: Cardiology Tags: ORIGINAL PAPERS: Heart Source Type: research
Blood pressure undulation of peripheral thrombolysis period in acute ischemic stroke is associated with prognosis
Conclusion:
Higher BPV and SBP from prior IVT to 72 h after IVT was associated with higher risk of stroke outcomes within 3 months.
Source: Journal of Hypertension - March 10, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Sex differences in blood pressure after stroke: a systematic review and meta-analysis
Conclusion:
This systematic review and meta-analysis indicates that women have higher SBP at the time of presentation with acute stroke. These differences are consistent with sex differences in hypertension patterns in older age, and may be explained by the fact that women are more likely to have a premorbid hypertension. This highlights the need for effective sex-specific blood pressure control in patients at high risk for stroke.
Source: Journal of Hypertension - August 31, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology Source Type: research
Early blood pressure lowering treatment in acute stroke. Ordinal analysis of vascular events in the Scandinavian Candesartan Acute Stroke Trial (SCAST)
Conclusion: Ordinal analysis of vascular events showed no overall effect of candesartan in the subacute phase of stroke. The effect of treatment given within 6 h of stroke onset appears promising, and will be addressed in ongoing trials. Ordinal analysis of vascular events is feasible and can be used in future trials.
Source: Journal of Hypertension - July 1, 2016 Category: Cardiology Tags: ORIGINAL PAPERS: Brain Source Type: research
Association of visit-to-visit variability in blood pressure and first stroke risk in hypertensive patients with chronic kidney disease
Conclusion:
In hypertensive adults with mild-to-moderate CKD, visit-to-visit variability in BP was significantly associated with the risk of subsequent first stroke.
Source: Journal of Hypertension - March 6, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology Source Type: research
Antihypertensive treatment decrease stroke occurrence: a prospective cohort study
Objective:
Among the risk factors of stroke, hypertension was one of the most important and modifiable factors. The current study aimed to assess whether antihypertensive treatment to ideal levels of blood pressure can eliminate stroke risk in a prospective cohort study.
Methods:
The Kailuan study was a prospective longitudinal cohort study on stroke risk factors and events. We analyzed association of baseline antihypertensive treatment efficacy with the risk of stroke during 11.0-year follow-up, and further evaluated association of newly antihypertensive treatment efficacy at 4-year follow-up with subsequent st...
Source: Journal of Hypertension - July 9, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research
Novel insights into stroke risk beyond resting and maximal bicycle exercise systolic blood pressure
Conclusion:
Stroke risk increased with increasing difference between resting and maximal exercise SBP, independent of BP at rest, suggesting that an exaggerated BP response to physical exercise may be an independent predictor of stroke.
Source: Journal of Hypertension - September 10, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: BP and other risk factor epidemiology Source Type: research
Risk factors predisposing to acute stroke in India: a prospective study
Conclusion:
The foremost risk factors for stroke in India, hypertension and diabetes, need to be controlled and treated like other global high-risk populations for stroke prevention. The NIHSS scores highlight the relationship between risk factors and stroke severity.
Source: Journal of Hypertension - October 15, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Risk factors Source Type: research
Blood pressure control and risk profile in poststroke survivors: a comparison with the general population
Conclusion: We found a high prevalence and poor control of major cardiovascular risk factors in patients surviving their first-ever ischemic stroke, thus showing poor implementation of guidelines for secondary prevention in clinical practice.
Source: Journal of Hypertension - September 9, 2015 Category: Cardiology Tags: ORIGINAL PAPERS: Stroke Source Type: research
Prestroke treatment with beta-blockers for hypertension is not associated with severity and poor outcome in patients with ischemic stroke: data from a national stroke registry
Background: Beta-blockers are not recommended as the initial therapy for hypertension. Reports on associations between use of beta-blockers and stroke severity are inconclusive. We assessed associations between prestroke use of beta-blockers and stroke severity, poststroke disability and death in a large group of hypertensive patients hospitalized with acute ischemic stroke.
Methods: All 3915 patients with ischemic stroke, treated prestroke for hypertension and registered in the National Acute Stroke ISraeli, were included. Treatment for hypertension was classified by medication type (beta-blockers, diuretics, calcium ant...
Source: Journal of Hypertension - March 2, 2017 Category: Cardiology Tags: ORIGINAL PAPERS: Therapeutic aspects Source Type: research
