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Source: Journal of Hypertension
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Total 283 results found since Jan 2013.
White-coat hypertension/effect is associated with higher arterial stiffness and stroke events
This study aimed to investigate the relationship between WCH/E, markers of cardiovascular risk and cerebrovascular events.
Methods:
This is a sub-group analysis of The Arterial Stiffness In lacunar Stroke and Transient ischemic attack (ASIST) study, which recruited 96 patients aged at least 40 years old with a diagnosis of transient ischemic attack or lacunar stroke in the preceding 14 days. Thirty-two patients with target blood pressure (clinic blood pressure
Source: Journal of Hypertension - March 10, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Association between oral health and cardiovascular outcomes in patients with hypertension: a nationwide cohort study
Conclusion:
Our study demonstrated that multiple dental caries were related to the risk of cardiovascular diseases in hypertensive patients. Better oral hygiene may attenuate the risk of cardiovascular events in hypertensive patients.
Source: Journal of Hypertension - January 16, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Optimal target blood pressure for major adverse cardiovascular and cerebrovascular events in hypertensive patients: a nationwide population-based study
Conclusion: Even though this observational study did not support inference of a causal relationship, a SBP of 120–129 mmHg and a DBP of 80–89 mmHg may be safely recommended considering the possibility of MACCE in Korean patients with hypertension. In addition, the target BP should be tailored individually according to age, sex, and comorbidities.
Source: Journal of Hypertension - December 10, 2021 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Blood pressure response during treadmill exercise testing and the risk for future cardiovascular events and new-onset hypertension
Objective:
The physiologic response to exercise may provide valuable prognostic information. We investigated the association of blood pressure (BP) measurements during exercise stress testing (EST) with long-term risk of myocardial infarction, stroke or death (major adverse cardiovascular event, MACE), as well as the development of new-onset hypertension.
Methods:
A retrospective analysis of treadmill ESTs (years 2005–2019) performed by the Bruce protocol in patients aged 35–75 years without a history of cardiovascular disease (n = 14 792; 48% women). BP was documented at rest, submaximal exercise (Bru...
Source: Journal of Hypertension - December 10, 2021 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Independent relationships between renal mechanisms and systemic flow, but not resistance to flow in primary hypertension in Africa
Aims:
Whether renal mechanisms of hypertension primarily translate into increases in systemic vascular resistance (SVR) in all populations is uncertain. We determined whether renal mechanisms associate with either increases in SVR (and impedance to flow) or systemic flow in a community of African ancestry.
Method:
In a South African community sampled across the full adult age range (n = 546), we assessed stroke volume (SV), peak aortic flow (Q), SVR, characteristic impedance (Zc) and total arterial compliance (TAC) from velocity and diameter measurements in the outflow tract (echocardiography) and central ar...
Source: Journal of Hypertension - November 19, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Renal aspects Source Type: research
Neurologically asymptomatic patients frequently present cerebral injuries during malignant hypertension: a MRI study
Conclusion:
PRES, recent hematoma, ischemic stroke and severe cerebral microangiopathy are common findings in MHT patients without neurological signs on admission. The impact of these findings on patient management, and their cerebrovascular and cognitive prognostic value, should be established. Brain MRI might need to become systematic in patients suffering from MHT episodes.
Source: Journal of Hypertension - November 19, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research
Global burden of cardiovascular diseases attributable to hypertension in young adults from 1990 to 2019
Conclusions:
Hypertension attributable CVDs burden in young adults has greatly increased from 1990 to 2019, with considerably spatiotemporal and sexual heterogeneity. The largest burden was borne by middle-income countries, especially by men. Establishment of geographically and sexually tailored strategies were needed to prevent hypertension-related CVDs in young adults.
Source: Journal of Hypertension - November 19, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology and genetics Source Type: research
The association between the Moyamoya disease susceptible gene RNF213 variant and incident cardiovascular disease in a general population: the Nagahama study
Objective:
An association between the Moyamoya disease susceptible gene ring finger protein 213 (RNF213) variant and ischemic stroke and coronary artery disease has been suggested in case-control studies. We aimed to investigate the possible association between the RNF213 variant and the incidence of cardiovascular disease in a general population.
Methods:
The study participants consisted of 9153 Japanese community residents without history of cardiovascular disease. The clinical parameters employed in this analysis were observed at baseline between 2008 and 2010. The RNF213 p.R4859K variant was determined by Ta...
Source: Journal of Hypertension - November 19, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology and genetics Source Type: research
Refining determinants of associations of visit-to-visit blood pressure variability with cardiovascular risk: results from the Action to Control Cardiovascular Risk in Diabetes Trial
Conclusion:
In ACCORD, the effect of BPv on adverse cardiovascular (but not cerebrovascular) outcomes is modified by baseline blood pressure and prior CVD. Recognizing these more nuanced relationships may help improve risk stratification and blood pressure management decisions as well as provide insight into potential underlying mechanisms.
Source: Journal of Hypertension - October 15, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Blood pressure measurement Source Type: research
Risk factors predisposing to acute stroke in India: a prospective study
Conclusion:
The foremost risk factors for stroke in India, hypertension and diabetes, need to be controlled and treated like other global high-risk populations for stroke prevention. The NIHSS scores highlight the relationship between risk factors and stroke severity.
Source: Journal of Hypertension - October 15, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Risk factors Source Type: research
Novel insights into stroke risk beyond resting and maximal bicycle exercise systolic blood pressure
Conclusion:
Stroke risk increased with increasing difference between resting and maximal exercise SBP, independent of BP at rest, suggesting that an exaggerated BP response to physical exercise may be an independent predictor of stroke.
Source: Journal of Hypertension - September 10, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: BP and other risk factor epidemiology Source Type: research
Impact of stroke work on the ability of left ventricular mass to account for pressure effects on function in a community with prevalent systemic flow-dependent hypertension
Aims:
To determine whether the confounding influence of stroke work on left ventricular mass (LVM) limits the ability of LVM to detect hypertensive LV dysfunction in systemic flow-dependent hypertension.
Methods:
In a community with prevalent systemic flow-dependent hypertension (n = 709), arterial haemodynamics, LVM and LV function were determined using central arterial pressure, aortic velocity and diameter measurements in the outflow tract, and echocardiography with tissue Doppler imaging.
Results:
In multivariate models, stroke work showed markedly stronger relations with LVM index (LVMI) than blo...
Source: Journal of Hypertension - September 10, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Cardiac function Source Type: research
Blood pressure, blood pressure variability and the risk of poststroke dementia
Conclusion:
Among patients with a recent noncardioembolic ischemic stroke, there appears to be a U-shaped association between achieved SBP and dementia. High blood pressure variability is associated with an increased risk of poststroke dementia.
Source: Journal of Hypertension - August 13, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Blood pressure variability Source Type: research
Isolated systolic and diastolic hypertension by the 2017 American College of Cardiology/American Heart Association guidelines and risk of cardiovascular disease: a large prospective cohort study
Objective:
The 2017 American College of Cardiology/American Heart Association blood pressure (BP) guidelines lowered the hypertension threshold from a SBP/DBP level of at least 140/90 mmHg to at least 130/80 mmHg. The cardiovascular impact of isolated systolic hypertension (ISH) and isolated diastolic hypertension (IDH) under the new definition remains unclear.
Methods:
We used data from the UK Biobank study, which is a prospective population-based cohort study. Participants were categorized into five groups: normal BP, normal high BP, ISH, IDH and systolic and diastolic hypertension. The primary endpoint fo...
Source: Journal of Hypertension - July 9, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: BP and other risk factor epidemiology Source Type: research
Cardiovascular outcomes in patients at high cardiovascular risk with previous myocardial infarction or stroke
Background:
Guidelines recommend to start blood pressure (BP)-lowering drugs also according to cardiovascular risk including history of cardiovascular events. We hypothesized that in patients with a history of myocardial infarction (MI), stroke, both or none of those, the index events predict the next event and have different SBP risk associations to different cardiovascular outcomes.
Design and measurements:
In this pooled posthoc, nonprespecified analysis, we assessed outcome data from high-risk patients aged 55 years or older with a history of cardiovascular events or proven cardiovascular disease, randomized...
Source: Journal of Hypertension - July 9, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: BP and other risk factor epidemiology Source Type: research
