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System-integrated technology-enabled model of care to improve the health of stroke patients in rural China: protocol for SINEMA--a cluster-randomized controlled trial
This study aims to develop a system-integrated technology-enabled intervention model of care (SINEMA) for the secondary prevention of stroke in rural China and to evaluate the effectiveness of the model compared with usual care.MethodsThe SINEMA model is being implemented and evaluated through a one-year cluster-randomized controlled trial in Nanhe County, Hebei Province in China. Fifty villages from five townships are randomized in a 1:1 ratio to either the intervention or the control arm (usual care) with a target to enroll 25 stroke survivors per village. Village doctors in the intervention arm 1) receive systematic cas...
Source: American Heart Journal - September 5, 2018 Category: Cardiology Source Type: research

Interim effects of salt substitution on urinary electrolytes and blood pressure in the China Salt Substitute and Stroke Study (SSaSS)
Publication date: Available online 7 January 2020Source: American Heart JournalAuthor(s): Liping Huang, Maoyi Tian, Jie Yu, Qiang Li, Yishu Liu, Xuejun Yin, Jason HY Wu, Matti Marklund, Yangfeng Wu, Nicole Li, Paul Elliot, Lijing L. Yan, Darwin R. Labarthe, Zhixin Hao, Jingpu Shi, Xiangxian Feng, Jianxin Zhang, Yuhong Zhang, Ruijuan Zhang, Bo ZhouAbstractThe Salt Substitute and Stroke Study is an ongoing 5-year large-scale cluster randomized trial investigating the effects of potassium-enriched salt substitute compared to usual salt on the risk of stroke. The study involves 600 villages and 20,996 individuals in rural Chin...
Source: American Heart Journal - January 7, 2020 Category: Cardiology Source Type: research

Rationale and design of the DEAR-OLD trial: randomized evaluation of routinely Deferred versus EARly invasive strategy in elderly patients of 75years or OLDer with non-ST-elevation myocardial infarction
Conclusions the DEAR-OLD trial is a prospective, nationwide, multi-center, non-inferiority designed, open-label randomized clinical trial evaluating efficacy and safety of routinely deferred invasive strategy compared with early invasive strategy in Chinese elderly patients with NSTEMI.
Source: American Heart Journal - November 9, 2017 Category: Cardiology Source Type: research

I-CARE randomized clinical trial integrating depression and acute coronary syndrome Care in low Resource Hospitals in China: Design and rationale
Publication date: Available online 21 May 2018 Source:American Heart Journal Author(s): Shenshen Li, James A. Blumenthal, Chuan Shi, Danielle Millican, Xian Li, Xin Du, Anushka Patel, Pei Gao, Elizabeth Delong, Pallab K. Maulik, Runlin Gao, Xin Yu, Yangfeng Wu Depression and acute coronary syndromes (ACS) are both common public health challenges. Patients with ACS often develop depression, which in turn adversely affects prognosis. Low-cost, sustainable, and effective service models that integrated depression care into the management of ACS patients to reduce depression and improve ACS outcomes are critically needed. Inte...
Source: American Heart Journal - May 22, 2018 Category: Cardiology Source Type: research

I-CARE randomized clinical trial integrating depression and acute coronary syndrome care in low-resource hospitals in China: Design and rationale
Publication date: August 2018 Source:American Heart Journal, Volume 202 Author(s): Shenshen Li, James A. Blumenthal, Chuan Shi, Danielle Millican, Xian Li, Xin Du, Anushka Patel, Pei Gao, Elizabeth Delong, Pallab K. Maulik, Runlin Gao, Xin Yu, Yangfeng Wu Depression and acute coronary syndromes (ACS) are both common public health challenges. Patients with ACS often develop depression, which in turn adversely affects prognosis. Low-cost, sustainable, and effective service models that integrate depression care into the management of ACS patients to reduce depression and improve ACS outcomes are critically needed. Integratin...
Source: American Heart Journal - June 20, 2018 Category: Cardiology Source Type: research

Contemporary Invasive Management and In-hospital Outcomes of Patients with Non-ST-segment Elevation Myocardial Infarction in China: Findings from China Acute Myocardial Infarction (CAMI) Registry
ConclusionInvasive management was underused and profoundly deferred among patients with NSTEMI in China. The risk-treatment paradox, procedure deferral and medical resources distribution imbalance may represent opportunities for improvement.
Source: American Heart Journal - June 6, 2019 Category: Cardiology Source Type: research

Contemporary invasive management and in-hospital outcomes of patients with non–ST-segment elevation myocardial infarction in China: Findings from China Acute Myocardial Infarction (CAMI) Registry
ConclusionInvasive management was underused and profoundly deferred among patients with NSTEMI in China. The risk-treatment paradox, procedure deferral and medical resources distribution imbalance may represent opportunities for improvement.
Source: American Heart Journal - June 29, 2019 Category: Cardiology Source Type: research